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ABA-GrowthBalance SIGNED

Growth balance regulation by SnRK1 under ABA-stress conditions

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ABA-GrowthBalance project word cloud

Explore the words cloud of the ABA-GrowthBalance project. It provides you a very rough idea of what is the project "ABA-GrowthBalance" about.

chemical    unbiased    activation    repression    expression    preliminary    axis    substrates    hormone    function    altogether    promotes    cellular    potentially    regulation    productivity    biochemical    energy    elucidate    plants    despite    genomics    protein    molecular    cell    modified    metabolism    yield    crop    stress    functional    mutant    extreme    player    readouts    tolerance    regulators    genetics    lab    physical    sensing    snrk    improvement    employed    rapamycin    temperatures    mechanisms    central    connection    adverse    partial    unknown    vast    successful    gene    negative    tor    interaction    aba    adaptive    activated    combination    kinases    downstream    largely    revealed    plant    assays    regulator    host    stresses    modulate    environmental    offs    survival    tackle    trade    snrk2    snrk1    expense    interactors    relevance    scarcity    microscopy    salinity    mechanism    trigger    deficient    kinase    implicated    triggers    signalling    water    suggesting    devastating   

Project "ABA-GrowthBalance" data sheet

The following table provides information about the project.

Coordinator
FUNDACAO CALOUSTE GULBENKIAN 

Organization address
address: AVENIDA BERNA 45
city: LISBOA
postcode: 1000
website: www.igc.gulbenkian.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Total cost 159˙815 €
 EC max contribution 159˙815 € (100%)
 Programme 1. H2020-EU.4. (SPREADING EXCELLENCE AND WIDENING PARTICIPATION)
 Code Call H2020-WF-01-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-10-01   to  2021-09-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACAO CALOUSTE GULBENKIAN PT (LISBOA) coordinator 159˙815.00

Map

 Project objective

In response to adverse environmental conditions, such as water scarcity, extreme temperatures or salinity plants trigger responses that promote stress tolerance and survival at the expense of growth. Despite the negative impact of stress on crop productivity how growth is modified by stress signalling pathways is largely unknown. One major component of the response to the most devastating stresses is ABA, a hormone that triggers cellular and whole-plant adaptive mechanisms via the activation of SnRK2 protein kinases. Another major player is the energy sensing SnRK1 protein kinase, which promotes plant stress tolerance and survival through the vast regulation of metabolism and gene expression. Preliminary results in the host lab have revealed deficient ABA responses in a partial SnRK1 loss-of-function mutant as well as the physical interaction between SnRK1 and the ABA-activated SnRK2 kinases, suggesting a functional connection between these two pathways. Furthermore, SnRK1 and SnRK2 have recently been implicated in the repression of a central growth regulator, the TOR (Target of Rapamycin) protein kinase. The aim of this proposal is to investigate the interaction between these two major stress-related kinases (SnRK1 and SnRK2) and to elucidate the mechanism(s) by which they modulate growth-promoting signalling pathways in response to ABA. To tackle the functional relevance of the SnRK1-SnRK2 connection, a combination of biochemical approaches, genetics, microscopy, cell-based assays and chemical genomics will be used. To identify growth regulators downstream of the SnRK axis, targeted analyses of TOR readouts will be employed in combination with unbiased analyses of SnRK1 interactors and substrates in ABA. Altogether this project will provide novel molecular insight on the trade-offs between stress tolerance and growth/yield that may potentially contribute to more successful crop improvement.

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The information about "ABA-GROWTHBALANCE" are provided by the European Opendata Portal: CORDIS opendata.

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