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SUSPENCE

SUSPension ENvironment for CEll culture

Total Cost €

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EC-Contrib. €

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Partnership

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 SUSPENCE project word cloud

Explore the words cloud of the SUSPENCE project. It provides you a very rough idea of what is the project "SUSPENCE" about.

dynamic    italian    amounts    36    morphological    74    forecast    larger    practically    damaging    customers    moving    thrice    space    technological    innovative    pilots    complexity    biotech    large    financial    global    48    suspension    deadline    solutions    commercial    received    manufacturing    revenues    vitro    drug    cell    suspence    labs    culture    unsustainable    start    productivity    intensive    total    irr    financially    maturity    damage    monitoring    release    market    months    stirred    scalability    mechanism    capacity    cellular    microgravity    explanatory    rotating    commercialization    keeps    september    seal    bioreactors    patent    labour    basic    contamination    mainly    interventions    advantages    expand    2018    suffer    confirmed    tank    solution    excellence    international    rotation    biological    strategies    competing    operation    red    standardization    manual    tests    cells    perfusion    size    chamber    conventional    dimensional    3rd    grow    limitations    disease    firms    november    benefits    commercialisation    parts    2d    requirement    industrialization    bioreactor    protected   

Project "SUSPENCE" data sheet

The following table provides information about the project.

Coordinator
BIOCOM - BIOMEDICAL COMPONENTS SRL 

Organization address
address: PIAZZALE DELLE BELLE ARTI, 2
city: ROMA
postcode: 196
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.cellexpansiondevices.com/home.html
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2019-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    BIOCOM - BIOMEDICAL COMPONENTS SRL IT (ROMA) coordinator 50˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Large-scale production of cells is essential for basic research, disease modelling and drug testing. However, scalability and standardization in cellular manufacturing are still major challenges: when large numbers of cells are required, conventional two-dimensional (2D) culture strategies, mainly based on manual, space- and labour-intensive interventions, are practically and financially unsustainable. Dynamic suspension allows large-scale production of cells, but current solutions on the market suffer from limitations in terms of cells damaging and potential contamination (stirred tank bioreactors) or high cost and complexity (rotating bioreactors). The SUSPENCE solution is a microgravity perfusion bioreactor, a highly innovative technological system that keeps cells in suspension in the culture chamber, allowing them to grow and reach maturity in dynamic conditions with no rotation mechanism or moving parts. SUSPENCE benefits have been confirmed by explanatory morphological and biological tests carried out on an in vitro cell culture. SUSPENCE advantages on competing solutions are: less cell damage, more easy-to-use, increased productivity, better monitoring and control and reduced operation costs. The design of SUSPENCE bioreactor is protected by an international patent application. The target users are research labs and red-biotech firms and; the market size has been estimated in over 6.000 potential customers in EU. Commercialization will start on the Italian market in 20 months from the start of the project, after pre-commercial pilots and industrialization, to expand on the EU market in 36 months and to reach the global market in month 48, after release of larger capacity devices. Forecast revenues are 9 M€/year in the 3rd year of commercialisation. The total financial requirement amounts to about 2.5 M€, with an IRR of 74%. SUSPENCE received thrice the “Seal of Excellence” by European Commission in 2018 (deadline of May, September, November).

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The information about "SUSPENCE" are provided by the European Opendata Portal: CORDIS opendata.

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