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SUSPENCE

SUSPension ENvironment for CEll culture

Total Cost €

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EC-Contrib. €

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Partnership

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 SUSPENCE project word cloud

Explore the words cloud of the SUSPENCE project. It provides you a very rough idea of what is the project "SUSPENCE" about.

total    solution    technological    labs    perfusion    biotech    capacity    november    basic    keeps    september    labour    solutions    competing    dynamic    size    stirred    rotating    italian    conventional    expand    strategies    thrice    mechanism    benefits    release    forecast    innovative    morphological    market    scalability    bioreactor    pilots    limitations    tank    confirmed    large    irr    monitoring    standardization    protected    international    vitro    damage    commercial    intensive    months    seal    revenues    microgravity    drug    suspence    patent    maturity    cellular    global    mainly    manufacturing    biological    advantages    productivity    suffer    manual    amounts    tests    explanatory    space    practically    3rd    interventions    dimensional    2018    red    culture    74    48    bioreactors    start    moving    grow    2d    commercialization    chamber    suspension    customers    damaging    rotation    36    parts    cells    unsustainable    financial    larger    contamination    firms    received    industrialization    requirement    operation    complexity    financially    cell    commercialisation    deadline    disease    excellence   

Project "SUSPENCE" data sheet

The following table provides information about the project.

Coordinator
BIOCOM - BIOMEDICAL COMPONENTS SRL 

Organization address
address: PIAZZALE DELLE BELLE ARTI, 2
city: ROMA
postcode: 196
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website http://www.cellexpansiondevices.com/home.html
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-06-01   to  2019-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    BIOCOM - BIOMEDICAL COMPONENTS SRL IT (ROMA) coordinator 50˙000.00

Map

 Project objective

Large-scale production of cells is essential for basic research, disease modelling and drug testing. However, scalability and standardization in cellular manufacturing are still major challenges: when large numbers of cells are required, conventional two-dimensional (2D) culture strategies, mainly based on manual, space- and labour-intensive interventions, are practically and financially unsustainable. Dynamic suspension allows large-scale production of cells, but current solutions on the market suffer from limitations in terms of cells damaging and potential contamination (stirred tank bioreactors) or high cost and complexity (rotating bioreactors). The SUSPENCE solution is a microgravity perfusion bioreactor, a highly innovative technological system that keeps cells in suspension in the culture chamber, allowing them to grow and reach maturity in dynamic conditions with no rotation mechanism or moving parts. SUSPENCE benefits have been confirmed by explanatory morphological and biological tests carried out on an in vitro cell culture. SUSPENCE advantages on competing solutions are: less cell damage, more easy-to-use, increased productivity, better monitoring and control and reduced operation costs. The design of SUSPENCE bioreactor is protected by an international patent application. The target users are research labs and red-biotech firms and; the market size has been estimated in over 6.000 potential customers in EU. Commercialization will start on the Italian market in 20 months from the start of the project, after pre-commercial pilots and industrialization, to expand on the EU market in 36 months and to reach the global market in month 48, after release of larger capacity devices. Forecast revenues are 9 M€/year in the 3rd year of commercialisation. The total financial requirement amounts to about 2.5 M€, with an IRR of 74%. SUSPENCE received thrice the “Seal of Excellence” by European Commission in 2018 (deadline of May, September, November).

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The information about "SUSPENCE" are provided by the European Opendata Portal: CORDIS opendata.

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