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ImmunoGrow

Making life-saving cancer therapies more widely available by simplifying production processes, reducing costs and enhancing patient safety through its patent-protected biomimicking mesh material.

Total Cost €

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EC-Contrib. €

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Partnership

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 ImmunoGrow project word cloud

Explore the words cloud of the ImmunoGrow project. It provides you a very rough idea of what is the project "ImmunoGrow" about.

engineered    healthcare    untreatable    sickest    manufacturers    helps    shown    capture    reduce    labour    significantly    cell    aggressive    requirement    independent    input    grey    market    2030    limitations    skilled    mimics    release    manufacture    changing    limited    automated    poor    600mn    produces    expects    anticipated    unless    patient    structure    2021    individualised    immune    seeking    mesh    costly    yield    addressable    business    q3    achieves    reducing    encounter    solutions    consumables    prices    feasibility    struggling    treatments    fund    cancers    expensive    priced    2019    ing    performance    8x    full    immunogrow    activation    round    harness    gold    500    life    patent    gmt    remission    citizens    lab    seed    natural    83    core    genetically    dynabeads    ltd    publically    15    initial    safer    prohibitive    lifesaving    conduct    standard    plan    tests    cancer    save    cleanroom    customers    trials    infrastructure    variability    patients    body    rates    simplifying    technologies    protected    treatment    operator    cheaper    car    475    therapies    cells    closed   

Project "ImmunoGrow" data sheet

The following table provides information about the project.

Coordinator
Grey Matter Technologies Limited 

Organization address
address: MERTON BREE ENNISCORTHY
city: WEXFORD
postcode: Y21 Y5V0
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website http://www.immunogrow.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-08-01   to  2019-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    Grey Matter Technologies Limited IE (WEXFORD) coordinator 50˙000.00

Map

 Project objective

Lifesaving cell-based CAR-T therapies have achieved remission rates of up to 83% for patients with the most aggressive and untreatable cancers. These therapies harness a patient’s own genetically engineered immune cells to target cancer cells. However, manufacturers are struggling to produce these individualised treatments at scale resulting in prohibitive prices as high as $475,000 per treatment. Unless solutions that address these limitations are provided, publically-funded EU healthcare systems & citizens will be priced out of these life-changing therapies.

The challenges they face include poor cell growth performance due to patient sample variability, limitations associated with equipment adopted from the research lab that require costly skilled labour, costly consumables and expensive cleanroom infrastructure.

Compared to the gold standard, Dynabeads, initial testing has shown that the ImmunoGrow technology produces an 8x higher cell yield which helps to save the sickest patients who have limited cells and significantly reduce the cost to manufacture these therapies by simplifying the process, reducing the requirement for skilled operator input and making this step both ‘closed’ and automated. ImmunoGrow achieves this through its patent-protected mesh structure that mimics the natural growth conditions cells encounter in the body.

Grey Matter Technologies (‘GMT’) Ltd. is seeking support to help fund trials with two identified customers as well to help it to conduct an independent set of tests on the product’s performance. Both these trials, as well as an associated business plan or feasibility study, will be core to the raising of a seed round of €500,000 in 2019 to further develop the technology with the release of a full-scale product anticipated for Q3 2021. GMT expects to capture 15% of the $600mn addressable T-Cell Activation market in 2030. In doing so, it will make these life changing treatments cheaper, safer and more widely available.

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The information about "IMMUNOGROW" are provided by the European Opendata Portal: CORDIS opendata.

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