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CLASSY SIGNED

Cell-Like ‘Molecular Assembly Lines’ of Programmable Reaction Sequences as Game-Changers in Chemical Synthesis

Total Cost €

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EC-Contrib. €

0

Partnership

0

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 CLASSY project word cloud

Explore the words cloud of the CLASSY project. It provides you a very rough idea of what is the project "CLASSY" about.

inspired    scientists    radically    sequences    networks    close    chemicals    compartmentalisation    constitute    game    waste    produces    catalytic    revolutionise    idea    fine    emissions    25    expertise    perform    regulate    compartmentalise    classy    programmable    reactor    vision    streams    interdisciplinary    individual    self    chemical    reaction    combined    technologies    manufactured    tech    generate    microfluidic    synthesise    multitude    specialised    vast    cell    effectors    changer    act    chemistry    zero    kg    drugs    multiple    enzyme    factory    pharmaceutical    europe    renewability    lines    innovative    scientific    ing    sequence    eliminate    true    catalysis    efficiency    toward    reactors    inefficient    living    modulate    overarching    single    synthesis    sustainability    pillars    peptide    molecular    replication    flow    capability    amounts    assembly    goals    energetic    peptides    sustainable    sme    brings    tools    replicating   

Project "CLASSY" data sheet

The following table provides information about the project.

Coordinator
UNIVERSIDAD AUTONOMA DE MADRID 

Organization address
address: CALLE EINSTEIN 3 CIUDAD UNIV CANTOBLANCO RECTORADO
city: MADRID
postcode: 28049
website: http://www.uam.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 3˙078˙073 €
 EC max contribution 3˙078˙073 € (100%)
 Programme 1. H2020-EU.1.2.1. (FET Open)
 Code Call H2020-FETOPEN-2018-2019-2020-01
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSIDAD AUTONOMA DE MADRID ES (MADRID) coordinator 492˙083.00
2    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH CH (ZUERICH) participant 585˙388.00
3    UNIVERSITAET GRAZ AT (GRAZ) participant 519˙600.00
4    STICHTING KATHOLIEKE UNIVERSITEIT NL (NIJMEGEN) participant 490˙000.00
5    BEN-GURION UNIVERSITY OF THE NEGEV IL (BEER SHEVA) participant 385˙396.00
6    MICRONIT MICROTECHNOLOGIES BV NL (ENSCHEDE) participant 376˙173.00
7    ACCELOPMENT AG CH (ZUERICH) participant 229˙431.00

Map

 Project objective

Chemical synthesis requires several process steps, produces vast amounts of waste today, for example 25–100 kg of waste per kg of product for pharmaceutical drugs, and is thus inefficient and not sustainable. Our vision is to become a real game-changer for chemical synthesis and eliminate many process steps, resulting in close to zero waste streams and a sustainable ‘chemical factory of the future’. To make this vision come true, the overarching aim of CLASSY is to develop a radically new type of chemical reactor inspired by the way in which living systems manage to modulate catalytic activity. The idea is that these reactors can self-regulate and perform multiple programmable reaction sequences by compartmentalisation of individual steps of the reaction sequence and replication of the molecular effectors that control the reactor’s catalytic activity. The use of microfluidic technology to compartmentalise individual steps of the reaction sequence and replicating molecular effectors to control the reactor activity constitute unique and highly innovative tools toward the project goals.

CLASSY will result in new flow reactors that act as cell-like molecular assembly lines, being able to synthesise a multitude of complex products in a single chemical reactor. These will have the capability to revolutionise the way chemical products, for example, fine chemicals and pharmaceutical drugs, are manufactured today.

CLASSY brings together 5 leading scientists in systems chemistry, replicating peptides, complex reaction networks, and peptide/enzyme catalysis. Their expertise will be combined with new microfluidic technology developed by a high-tech SME and an SME specialised in dissemination and exploitation of results. This highly interdisciplinary consortium will generate new scientific knowledge and novel technologies to support essential pillars for Europe`s future, such as renewability, sustainability, zero waste emissions and energetic efficiency.

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The information about "CLASSY" are provided by the European Opendata Portal: CORDIS opendata.

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