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PeptiCHIP SIGNED

PEPTICHIP: Streamlined identification of tumour neoantigens for personalised anti-cancer immunotherapy

Total Cost €

0

EC-Contrib. €

0

Partnership

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 PeptiCHIP project word cloud

Explore the words cloud of the PeptiCHIP project. It provides you a very rough idea of what is the project "PeptiCHIP" about.

solidify    accurate    routes    technological    analysing    purification    commercial    2021    explore    team    start    vincenzo    impractically    neoantigens    patient    optimal    time    invoke    accurately    erc    ip    viability    university    powerful    anti    majority    inaccurate    vulnerabilities    fails    cerullo    immune    toward    chip    strategies    business    identification    immunotherapies    device    prepare    position    solid    weeks    expensive    innovative    model    tune    strategy    emerged    personalisation    treat    proof    unable    minute    experts    2016    antigens    either    material    fine    first    personalised    rapid    spin    microfluidic    types    therapies    consuming    standardised    thereby    gain    immunotherapeutic    tools    helsinki    human    single    market    tissue    months    commercialisation    peptichip    targetable    laborious    full    quantities    pepticrad    prof    neoantigen    off    conserving    permits    poc    patients    tumour    unleashing    vary    degree    condenses    cancers    ascertain   

Project "PeptiCHIP" data sheet

The following table provides information about the project.

Coordinator
HELSINGIN YLIOPISTO 

Organization address
address: YLIOPISTONKATU 3
city: HELSINGIN YLIOPISTO
postcode: 14
website: www.helsinki.fi

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2019
 Duration (year-month-day) from 2019-10-01   to  2021-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HELSINGIN YLIOPISTO FI (HELSINGIN YLIOPISTO) coordinator 150˙000.00

Map

 Project objective

Immunotherapeutic strategies have emerged as powerful tools to treat many types of cancers. However, the majority of patients still fails to respond to immunotherapies as targetable tumour characteristics vary from patient to patient. Thus, a greater degree of personalisation is required to fine-tune immunotherapies to the specific vulnerabilities of each patient’s tumour. While therapies that target tumour-specific antigens (neoantigens) invoke a strong and specific anti-tumour immune response, we are currently unable to accurately identify patient-specific neoantigens. Current neoantigen identification and purification methods either require impractically large quantities of tumour material or are laborious, expensive, time-consuming (weeks or months) and inaccurate. As part of ERC project PEPTICRAD (2016-2021), Prof. Vincenzo Cerullo at the University of Helsinki has developed a novel microfluidic chip-based device (PeptiCHIP) which condenses the neoantigen purification steps into a single chip capable of accurately analysing minute quantities of human tumour tissue. PeptiCHIP permits cost-effective, rapid, sample-conserving, user-friendly, accurate and standardised tumour neoantigen identification, thereby unleashing the full potential of personalised anti-tumour immunotherapies. In this ERC PoC project, a team of technological and commercial experts will ascertain the technical and commercial viability of the innovative PeptiCHIP device. We will prepare the first steps toward the start-up of a spin-off by defining the most optimal business strategy and model. Furthermore, we will explore the technical potential of the PeptiCHIP and solidify our IP-position. We will develop a solid business strategy based on the technological aspects, the market needs and trends. Finally, during this project we will gain technical and commercial proof-of-concept, providing the necessary information for potential commercialisation routes.

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The information about "PEPTICHIP" are provided by the European Opendata Portal: CORDIS opendata.

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