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PeptiCHIP SIGNED

PEPTICHIP: Streamlined identification of tumour neoantigens for personalised anti-cancer immunotherapy

Total Cost €

0

EC-Contrib. €

0

Partnership

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 PeptiCHIP project word cloud

Explore the words cloud of the PeptiCHIP project. It provides you a very rough idea of what is the project "PeptiCHIP" about.

material    minute    team    prof    invoke    prepare    neoantigen    university    pepticrad    tools    strategies    therapies    types    immune    tissue    fine    chip    business    time    unleashing    powerful    majority    degree    permits    experts    erc    patient    microfluidic    analysing    ip    personalisation    inaccurate    antigens    gain    condenses    market    commercial    rapid    first    tumour    impractically    identification    position    cerullo    spin    expensive    personalised    solidify    vincenzo    consuming    2016    accurately    immunotherapies    laborious    purification    treat    strategy    peptichip    immunotherapeutic    ascertain    human    patients    explore    single    fails    proof    off    helsinki    anti    vulnerabilities    solid    toward    neoantigens    conserving    quantities    thereby    either    commercialisation    unable    model    vary    weeks    innovative    emerged    targetable    viability    full    technological    tune    cancers    standardised    device    accurate    months    poc    start    routes    optimal    2021   

Project "PeptiCHIP" data sheet

The following table provides information about the project.

Coordinator
HELSINGIN YLIOPISTO 

Organization address
address: YLIOPISTONKATU 3
city: HELSINGIN YLIOPISTO
postcode: 14
website: www.helsinki.fi

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Finland [FI]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2019
 Duration (year-month-day) from 2019-10-01   to  2021-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    HELSINGIN YLIOPISTO FI (HELSINGIN YLIOPISTO) coordinator 150˙000.00

Map

 Project objective

Immunotherapeutic strategies have emerged as powerful tools to treat many types of cancers. However, the majority of patients still fails to respond to immunotherapies as targetable tumour characteristics vary from patient to patient. Thus, a greater degree of personalisation is required to fine-tune immunotherapies to the specific vulnerabilities of each patient’s tumour. While therapies that target tumour-specific antigens (neoantigens) invoke a strong and specific anti-tumour immune response, we are currently unable to accurately identify patient-specific neoantigens. Current neoantigen identification and purification methods either require impractically large quantities of tumour material or are laborious, expensive, time-consuming (weeks or months) and inaccurate. As part of ERC project PEPTICRAD (2016-2021), Prof. Vincenzo Cerullo at the University of Helsinki has developed a novel microfluidic chip-based device (PeptiCHIP) which condenses the neoantigen purification steps into a single chip capable of accurately analysing minute quantities of human tumour tissue. PeptiCHIP permits cost-effective, rapid, sample-conserving, user-friendly, accurate and standardised tumour neoantigen identification, thereby unleashing the full potential of personalised anti-tumour immunotherapies. In this ERC PoC project, a team of technological and commercial experts will ascertain the technical and commercial viability of the innovative PeptiCHIP device. We will prepare the first steps toward the start-up of a spin-off by defining the most optimal business strategy and model. Furthermore, we will explore the technical potential of the PeptiCHIP and solidify our IP-position. We will develop a solid business strategy based on the technological aspects, the market needs and trends. Finally, during this project we will gain technical and commercial proof-of-concept, providing the necessary information for potential commercialisation routes.

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The information about "PEPTICHIP" are provided by the European Opendata Portal: CORDIS opendata.

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