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CAST SIGNED

Active Monitoring of Cancer As An Alternative To Surgery

Total Cost €

0

EC-Contrib. €

0

Partnership

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Project "CAST" data sheet

The following table provides information about the project.

Coordinator
ACADEMISCH ZIEKENHUIS LEIDEN 

Organization address
address: ALBINUSDREEF 2
city: LEIDEN
postcode: 2333 ZA
website: www.lumc.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 4˙111˙553 €
 EC max contribution 4˙111˙553 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2019
 Funding Scheme MSCA-ITN-ETN
 Starting year 2019
 Duration (year-month-day) from 2019-11-01   to  2023-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    ACADEMISCH ZIEKENHUIS LEIDEN NL (LEIDEN) coordinator 531˙239.00
2    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) participant 606˙345.00
3    EDINBURGH MOLECULAR IMAGING LIMITED UK (EDINBURGH) participant 303˙172.00
4    THE UNIVERSITY OF MANCHESTER UK (MANCHESTER) participant 303˙172.00
5    KAROLINSKA INSTITUTET SE (STOCKHOLM) participant 281˙982.00
6    SURGIMAB SAS FR (MONTPELLIER) participant 274˙802.00
7    UNIVERSITE DE STRASBOURG FR (STRASBOURG) participant 274˙802.00
8    PERCUROS BV NL (LEIDEN) participant 265˙619.00
9    STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS NL (AMSTERDAM) participant 265˙619.00
10    UNIVERSITA DEGLI STUDI DI CAMERINO IT (CAMERINO) participant 261˙499.00
11    SIMFO SPEZIELLE IMMUNOLOGIE FORSCHUNG UND ENTWICKLUNG GMBH DE (BAYREUTH) participant 252˙788.00
12    UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS DE (GOETTINGEN) participant 252˙788.00
13    FUNDACAO D. ANNA SOMMER CHAMPALIMAUD E DR. CARLOS MONTEZ CHAMPALIMAUD PT (LISBOA) participant 237˙720.00

Map

 Project objective

When a patient is discovered to have cancer, one of the primary goals is to have the tumour removed by surgery. Although this provides excellent oncological control, it is associated with morbidity and functional problems in cancer survivors. Recent studies have shown that the immediacy to perform a resection does not always lead to improved clinical outcome. Furthermore, cancer surgery can often lead to complications where the quality of life for the patient is compromised by toxic side effects and /or damage to nerves, organs or healthy tissues. A number of recent clinical trials in the field of cancer surgery have advocated the concept of watch and wait, watchful waiting, active monitoring or surveillance, which are terms used to describe a monitoring strategy for cancer. The concept may be antithetical but the functional advantage of these alternatives is clear even though there is some concern about the risk. Though the evidence is still weak, current studies suggest that with adequate selection and follow-up, this oncological risk is small. A major consideration for clinicians is now to maintain quality of life for all patients. Our objective in this proposal is to implement novel approaches so that cancer surgery can be avoided, where we aim to (a) develop new monitoring technologies from industry so that the surveillance window can be increased to allow for better treatment options over time and to avoid surgery, (b) develop new ‘watch and wait’ strategies in order to study the behaviour of the cancer so that any risks to the patient can be minimised leading to a better clinical outcome and (c) train a new generation of preclinical and clinical scientists to be able to implement this new concept as standard of care and to maximise the benefits of an active monitoring policy.

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The information about "CAST" are provided by the European Opendata Portal: CORDIS opendata.

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