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InSiDe SIGNED

Integrated silicon photonics for Cardiovascular Disease monitoring

Total Cost €

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EC-Contrib. €

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Partnership

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InSiDe project word cloud

Explore the words cloud of the InSiDe project. It provides you a very rough idea of what is the project "InSiDe" about.

invasive hypertensive stiffness successful outcome therapies contraction cheap handheld monitor adoption realizations community algorithms diagnosis demonstrated stages gives clinical cardiology miniaturized ict monitoring translation prove dramatically aortic disease efficacy beat guidelines patients manufacturability stenosis silicon signal multiple building physician realize cardis reduces diagnostic photonics electronics inside time accelerate rationale healthcare valvular signals velocity improves 644798 arterial appropriate outline doppler patient medtronic medical follow capability recommended optics onboard device laser tool imaging wave outside cardiac society identification manufacturable near unmet feasibility therapy driving diseases ensures abnormalities tools solving drive interferometer interpretation pulse efficient fact cardiovascular earlier volumes industrialization

Project "InSiDe" data sheet

The following table provides information about the project.

Coordinator	INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM Organization address address: KAPELDREEF 75 city: LEUVEN postcode: 3001 website: www.imec.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Belgium [BE]
Total cost	5˙841˙350 €
EC max contribution	4˙948˙385 € (85%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2019-2
Funding Scheme	IA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2023-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM Organization address address: KAPELDREEF 75 city: LEUVEN postcode: 3001 website: www.imec.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	coordinator	654˙937.00
2	MEDTRONIC BAKKEN RESEARCH CENTER B.V. MEDTRONIC BAKKEN RESEARCH CENTER B.V. Organization address address: ENDEPOLSDOMEIN 5 city: MAASTRICHT postcode: 6229GW website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	participant	1˙015˙875.00
3	UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Organization address address: WESTERN ROAD city: Cork postcode: T12 YN60 website: www.ucc.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (Cork)	participant	510˙051.00
4	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	490˙625.00
5	UNIVERSITEIT MAASTRICHT UNIVERSITEIT MAASTRICHT Organization address address: Minderbroedersberg 4-6 city: MAASTRICHT postcode: 6200 MD website: http://www.maastrichtuniversity.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	participant	484˙000.00
6	MICROSEMI SEMICONDUCTOR LIMITED MICROSEMI SEMICONDUCTOR LIMITED Organization address address: PHASE 2 CASTLEGATE BUSINESS PARK city: GWENT postcode: NP26 5YW website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (GWENT)	participant	483˙647.00
7	ARGOTECH AS ARGOTECH AS Organization address address: HOLUBOVA 978 city: NACHOD postcode: 547 01 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (NACHOD)	participant	458˙062.00
8	UNIVERSITEIT GENT UNIVERSITEIT GENT Organization address address: SINT PIETERSNIEUWSTRAAT 25 city: GENT postcode: 9000 website: http://www.ugent.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (GENT)	participant	431˙436.00
9	POLITECNICO DI TORINO POLITECNICO DI TORINO Organization address address: CORSO DUCA DEGLI ABRUZZI 24 city: TORINO postcode: 10129 website: www.polito.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (TORINO)	participant	293˙750.00
10	FUNDICO BVBA FUNDICO BVBA Organization address address: GRUUTHUSELAAN 19 city: OOSTKAMP postcode: 8020 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (OOSTKAMP)	participant	126˙000.00

Map

Project objective

The rationale for Medtronic and partners to propose the InSiDe project is the unmet need of the medical community for reliable, non-invasive, cheap and easy-to-use tools able to identify and characterize different stages of cardiovascular diseases. Solving this need ensures the early adoption of the appropriate therapies, dramatically reduces healthcare costs and importantly, improves patient outcome. In fact, monitoring arterial stiffness by measurement of the aortic pulse wave velocity has been demonstrated to be a crucial need for the management of hypertensive patients and it is recommended in the European Society of Cardiology Guidelines. In addition, the early identification of arterial stenosis and cardiac contraction abnormalities can be used to drive earlier therapy adoption and to improve patient’s response in cardiac (valvular) disease. Building on the realizations of the successful CARDIS (H2020-ICT-644798) project, the objective of InSiDe is to accelerate access to a new diagnostic device, based on silicon photonics technology, able to monitor cardiovascular diseases and to prove its efficacy in driving a timely therapy institution and its related follow-up. We will: -Develop an efficient miniaturized laser Doppler interferometer supported by a manufacturable package with integrated imaging optics and by electronics for control of the laser interferometer with onboard near-real time signal processing capability. -Develop algorithms for translation of the interferometer signals to beat-to-beat measurement results relevant for monitoring and diagnosis of selected cardiovascular parameters. -Prove the device efficacy in multiple clinical feasibility studies inside and outside the consortium. -Outline a path to industrialization and manufacturability. In this way InSiDe will realize a low-cost handheld, robust diagnostic tool, manufacturable in high-volumes. The diagnostic tool gives immediate results for physician’s interpretation.

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