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AMPLITUDE SIGNED

Advanced Multimodal Photonics Laser Imaging Tool for Urothelial Diagnosis in Endoscopy

Total Cost €

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EC-Contrib. €

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Partnership

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AMPLITUDE project word cloud

Explore the words cloud of the AMPLITUDE project. It provides you a very rough idea of what is the project "AMPLITUDE" about.

technologies possibilities lasers multiple there 1650 optical achievable deeper bladder confocal 1870 relatively absence raman techniques enhanced performance wavelengths window capability breakthrough biological 1700 spectroscopy diagnosis molecular imaging metabolic laser ultrafast overcoming resolution limitations guide suitable characterisation spectral modal biopsy cellular biophotonics urgent linear compact progressing examined pathohistological tandem pioneering appealing spectroscopic endoscopic autofluorescence nir tumours motivated adoption depths functioning generation lesion device reflectance grading invasiveness nm fibre meet proposes harmonic bio wavelength questions staging tightly of label combining amplitude sources twice 850 exhaustive medical free cancer outstanding region unexplored spontaneous output photon morphological appropriate form tissue microscopy levels vivo efficient instrument additional

Project "AMPLITUDE" data sheet

The following table provides information about the project.

Coordinator	TAMPEREEN KORKEAKOULUSAATIO SR Organization address address: KALEVANTIE 4 city: TAMPERE postcode: 33100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Finland [FI]
Total cost	4˙656˙750 €
EC max contribution	4˙486˙750 € (96%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2019-2
Funding Scheme	RIA
Starting year	2020
Duration (year-month-day)	from 2020-01-01 to 2023-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	TAMPEREEN KORKEAKOULUSAATIO SR TAMPEREEN KORKEAKOULUSAATIO SR Organization address address: KALEVANTIE 4 city: TAMPERE postcode: 33100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (TAMPERE)	coordinator	710˙000.00
2	ASTON UNIVERSITY ASTON UNIVERSITY Organization address address: ASTON TRIANGLE city: BIRMINGHAM postcode: B4 7ET website: www.aston.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BIRMINGHAM)	participant	620˙657.00
3	FEMTONICS KUTATO ES FEJLESZTO KORLATOLT FELELOSSEGU TARSASAG FEMTONICS KUTATO ES FEJLESZTO KORLATOLT FELELOSSEGU TARSASAG Organization address address: TUZOLTO UTCA 59 city: BUDAPEST postcode: 1094 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	HU (BUDAPEST)	participant	593˙740.00
4	CONSIGLIO NAZIONALE DELLE RICERCHE CONSIGLIO NAZIONALE DELLE RICERCHE Organization address address: PIAZZALE ALDO MORO 7 city: ROMA postcode: 185 website: www.cnr.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	512˙000.00
5	LEONI FIBER OPTICS GMBH LEONI FIBER OPTICS GMBH Organization address address: MUHLDAMM 6 city: NEUHAUS SCHIERSCHNITZ postcode: 96524 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (NEUHAUS SCHIERSCHNITZ)	participant	451˙765.00
6	FUNDACIO INSTITUT DE CIENCIES FOTONIQUES FUNDACIO INSTITUT DE CIENCIES FOTONIQUES Organization address address: AVINGUDA CARL FRIEDRICH GAUSS 3 city: Castelldefels postcode: 8860 website: www.icfo.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (Castelldefels)	participant	396˙250.00
7	AMPLICONYX OY AMPLICONYX OY Organization address address: LAUTAKATONKATU 18 city: TAMPERE postcode: 33580 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (TAMPERE)	participant	375˙687.00
8	UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA Organization address address: PIAZZA DELL'ATENEO NUOVO 1 city: MILANO postcode: 20126 website: www.unimib.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (MILANO)	participant	330˙400.00
9	UNIVERSITA DEGLI STUDI DI FIRENZE UNIVERSITA DEGLI STUDI DI FIRENZE Organization address address: Piazza San Marco 4 city: Florence postcode: 50121 website: http://www.unifi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (Florence)	participant	262˙500.00
10	MODUS RESEARCH AND INNOVATION LIMITED MODUS RESEARCH AND INNOVATION LIMITED Organization address address: 7-11 MELVILLE STREET city: EDINBURGH postcode: EH3 7PE website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (EDINBURGH)	participant	233˙750.00
11	HC PHOTONICS CORPORATION LIMITED HC PHOTONICS CORPORATION LIMITED Organization address address: TECHNOLOGY ROAD V 2 F4 city: HSINCHU postcode: 30078 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	TW (HSINCHU)	participant	0.00

Map

Project objective

There is an absence of lasers with the necessary wavelengths and characteristics to access the possibilities for deeper high-resolution biological tissue imaging in the third bio-window between 1650 nm and 1870 nm. Motivated by recent breakthrough results in multi-photon imaging at twice the depths currently achievable, we will meet the urgent need for new sources to address the outstanding research questions in this spectral region. Results will guide and enable instrument development in this appealing and relatively unexplored biophotonics imaging wavelength range.

The AMPLITUDE consortium proposes a new concept of label-free, multi-modal microscopy and endoscopic imaging operating in this new wavelength region with multiple imaging and spectroscopic technologies, including NIR confocal reflectance microscopy, multi-photon microscopy and spontaneous Raman spectroscopy.

By progressing ultrafast fibre laser developments at 1700 nm, we will deliver new imaging capabilities in an appropriate form factor and at cost suitable for widespread adoption. This will be further enhanced by providing additional output at 850 nm using second harmonic generation from one integrated laser device.

This will enable a pioneering new compact and efficient multi-modal capability combining confocal and non-linear imaging techniques, overcoming performance limitations in medical and biological imaging applications, including improved pathohistological staging of tumours and in-vivo endoscopic assessment of depth of lesion invasiveness. Deeper multi-photon microscopy with autofluorescence imaging of cellular metabolic conditions, whose aspects are tightly related to cellular functioning and to cancer, implemented in tandem with Raman spectroscopy will provide exhaustive characterisation of the examined tissue at morphological, metabolic and molecular levels, allowing in-vivo optical biopsy for bladder cancer diagnosis, grading and staging.

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The information about "AMPLITUDE" are provided by the European Opendata Portal: CORDIS opendata.

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