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cONCReTE SIGNED

DevelOpmeNt of Cancer RNA TherapEutics

Total Cost €

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EC-Contrib. €

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Partnership

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 cONCReTE project word cloud

Explore the words cloud of the cONCReTE project. It provides you a very rough idea of what is the project "cONCReTE" about.

spreading    ideal    competitiveness    non    codingrnas    molecules    formulation    transduction    accumulation    synergetic    life    models    aptamers    joint    environments    functional    business    regulate    designed    signal    stable    therapies    applicability    members    ing    scientists    malignant    quality    governing    therapeutic    inhibiting    innovative    ncrna    classes    inter    training    tumor    molecular    identification    class    platform    delivering    personalized    patients    safe    experts    efficacy    monitor    expression    interdisciplinary    drug    oncology    animal    vivo    novels    qol    reveal    ncrnas    clinical    links    staff    exposed    genes    sme    imaging    performed    epigenetics    international    skills    tools    form    appropriate    sectoral    cells    concert    types    biological    contribution    network    tumors    potentially    academic    complementary    cancer    toxic    cell    appropriately    exchange    teams    cargoes    oncogenic    derivatives    progression    education    biology   

Project "cONCReTE" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II 

Organization address
address: CORSO UMBERTO I, 40
city: NAPOLI
postcode: 80138
website: www.unina.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Total cost 2˙060˙800 €
 EC max contribution 2˙060˙800 € (100%)
 Programme 1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
 Code Call H2020-MSCA-RISE-2019
 Funding Scheme MSCA-RISE
 Starting year 2020
 Duration (year-month-day) from 2020-05-01   to  2024-04-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II IT (NAPOLI) coordinator 165˙600.00
2    PERCUROS BV NL (LEIDEN) participant 174˙800.00
3    JENACELL GMBH DE (JENA) participant 128˙800.00
4    ASSOCIAZIONE HAND IN HAND IT (NEMI) participant 124˙200.00
5    CLINICA MEDITERRANEA SPA IT (NAPOLI) participant 124˙200.00
6    TACIT BIO INNOVATION LIMITED UK (SUTTON COLDFIELD) participant 119˙600.00
7    TECOBIOSCIENCES GMBH DE (LANDSHUT) participant 119˙600.00
8    CONSIGLIO NAZIONALE DELLE RICERCHE IT (ROMA) participant 110˙400.00
9    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM NL (ROTTERDAM) participant 110˙400.00
10    FUNDACIO INSTITUT DE RECERCA CONTRA LA LEUCEMIA JOSEP CARRERAS ES (BARCELONA) participant 110˙400.00
11    FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA ES (PAMPLONA) participant 110˙400.00
12    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 110˙400.00
13    PROGREDUM GMBH DE (KAISERSLAUTERN) participant 110˙400.00
14    RHEINISCHE FRIEDRICH-WILHELMS-UNIVERSITAT BONN DE (BONN) participant 110˙400.00
15    UNIVERSITAET INNSBRUCK AT (INNSBRUCK) participant 110˙400.00
16    UNIVERSITATEA DE MEDICINA SI FARMACIE IULIU HATIEGANU CLUJ-NAPOCA RO (Cluj-Napoca) participant 110˙400.00
17    XENOPAT SL ES (HOSPITALET DE LLOBREGAT) participant 110˙400.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Non-codingRNAs (ncRNAs) represent a large class of molecules that in concert regulate the expression of genes involved in the key pathways governing cancer development and progression. They represent ideal targets for personalized cancer therapies and if appropriately designed they can provide specific, non-toxic and effective therapeutic tools. The identification of novel therapeutic ncRNAs and the design of their appropriate formulation is a key aspect for their clinical applicability. RISE- cONCReTE aims to form an international and inter-sectoral network of organizations working on a joint research programme on the development of a safe ncRNA-based drug. RISE- cONCReTE teams up experts in the fields of Molecular Oncology, Epigenetics, Signal transduction, Animal models, Therapeutic delivery and Imaging, business, and education. The participants will exchange skills, knowledge and staff members that will be exposed to synergetic and complementary research environments. RISE- cONCReTE will undertake an integrated approach to reveal novels functional links between ncRNAs and oncogenic pathways. We will: a) characterize novel classes of tumor-associated ncRNAs; b) investigate the impact of ncRNAs on key aspects of tumor cell biology; c) develop cargoes (e.g. aptamers) for delivering therapeutic ncRNA derivatives into specific cancer cell types. By using innovative in vivo imaging tools, we will monitor the accumulation of target ncRNAs in cancer cells and evaluate their biological efficacy in inhibiting the growth and spreading of malignant tumors. The resulting approaches will provide stable and effective tools thus potentially improving the quality of life (QOL) of the cancer patients. Further, the joint research and training programme of RISE- cONCReTE will be performed in academic institutions and SME to provide a unique interdisciplinary platform for scientists with a significant contribution to EU competitiveness.

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The information about "CONCRETE" are provided by the European Opendata Portal: CORDIS opendata.

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