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GUT3D-PLATE SIGNED

Ready-to-use cell culture plates for gut 3D models

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 GUT3D-PLATE project word cloud

Explore the words cloud of the GUT3D-PLATE project. It provides you a very rough idea of what is the project "GUT3D-PLATE" about.

primary    interactions    market    ipr    printing    community    protecting    investing    tools    specialized    roadmap    commercial    toxicity    human    physiology    scaffolds    device    business    efficacy    architecture    mimicking    gut3d    manner    cros    capacities    societal    drug    predict    attractive    intestinal    stages    proper    lines    provides    accurately    innovative    light    investors    soft    platforms    lack    significantly    fabricate    dimensions    microbiome    plate    attract    cells    generation    intestine    reproducible    vitro    industry    crypt    inserts    biomedical    ready    animal    plan    cell    designing    conventional    explore    poc    obtain    comiet    3d    mechanical    commercialize    morphologies    disease    assays    tissue    feasibility    models    erc    ease    benefit    materials    screening    pharma    customize    predictive    generating    mimic    devoted    hydrogel    analyzing    modeling    villus    compatible    efforts    treatment    reduce    substrates    culture   

Project "GUT3D-PLATE" data sheet

The following table provides information about the project.

Coordinator
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA 

Organization address
address: CARRER BALDIRI REIXAC PLANTA 2A 10-12
city: BARCELONA
postcode: 8028
website: http://www.ibecbarcelona.eu

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 0 €
 EC max contribution 150˙000 € (0%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2019-PoC
 Funding Scheme ERC-POC-LS
 Starting year 2020
 Duration (year-month-day) from 2020-06-01   to  2021-11-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA ES (BARCELONA) coordinator 150˙000.00

Map

 Project objective

3D cell culture models are considered the next-generation in vitro models. Several efforts are being devoted to better mimic human physiology and predict drug efficacy. In case of the intestinal tissue models, the 3D architecture of the intestinal tissue and the soft mechanical properties have been identified as key factors to obtain models with improved predictive capacities. However, there is a lack of low-cost and ease-to-use intestinal tissue models that encompass both elements. In the COMIET ERC project, we developed 3D cell culture scaffolds that accurately mimic the villus and crypt morphologies of the human intestine using soft materials. We used an innovative light-based approach to fabricate hydrogel scaffolds with the proper dimensions and mechanical properties of the tissue, in a reproducible manner. This ERC PoC GUT3D-PLATE will develop further the technology and customize a 3D low cost printing device to be able to fabricate ready-to-commercialize 3D cell culture substrates mimicking the intestinal physiology. These substrates will be provided as ready-to-use cell culture inserts, compatible with conventional assays and without the need of specialized equipment. The scaffolds support the growth of conventional intestinal cell lines and primary-derived cells and can be used as platforms for drug screening, disease modeling and microbiome interactions. GUT3D-PLATE will also explore the commercial feasibility of the product by protecting the IPR, analyzing the market, and designing a business plan that provides the roadmap to attract investors. The intestinal 3D culture models will be attractive not only to the biomedical research community, but also to the pharma industry and CROs as they are increasingly investing in tools that better predict drug treatment efficacy and toxicity at early stages of the drug development process. This will reduce significantly the need for animal models and the overall cost, generating a major societal benefit.

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The information about "GUT3D-PLATE" are provided by the European Opendata Portal: CORDIS opendata.

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