EMTICS

European Multicentre Tics in Children Studies

 Coordinatore ACADEMISCH ZIEKENHUIS GRONINGEN 

 Organization address address: Hanzeplein 1
city: GRONINGEN
postcode: 9713 GZ

contact info
Titolo: Dr.
Nome: Pieter J.
Cognome: Hoekstra
Email: send email
Telefono: +31 50 3681100
Fax: +31 50 3681120

 Nazionalità Coordinatore Netherlands [NL]
 Sito del progetto http://www.emtics.eu/
 Totale costo 8˙067˙587 €
 EC contributo 6˙000˙000 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2011-two-stage
 Funding Scheme CP-FP
 Anno di inizio 2011
 Periodo (anno-mese-giorno) 2011-12-01   -   2017-05-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    ACADEMISCH ZIEKENHUIS GRONINGEN

 Organization address address: Hanzeplein 1
city: GRONINGEN
postcode: 9713 GZ

contact info
Titolo: Dr.
Nome: Pieter J.
Cognome: Hoekstra
Email: send email
Telefono: +31 50 3681100
Fax: +31 50 3681120

NL (GRONINGEN) coordinator 473˙339.00
2    DEMOCRITUS UNIVERSITY OF THRACE

 Organization address address: PANEPISTIMIOUPOLI
city: KOMOTINI
postcode: 69100

contact info
Titolo: Prof.
Nome: Peristera
Cognome: Paschou
Email: send email
Telefono: 302551000000
Fax: 302551000000

EL (KOMOTINI) participant 746˙941.00
3    ISTITUTO SUPERIORE DI SANITA

 Organization address address: Viale Regina Elena 299
city: ROMA
postcode: 161

contact info
Titolo: Dr.
Nome: Rosa Maria
Cognome: Martoccia
Email: send email
Telefono: +39 06 49902688
Fax: +39 06 49903007

IT (ROMA) participant 713˙967.00
4    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

 Organization address address: GESCHWISTER SCHOLL PLATZ 1
city: MUENCHEN
postcode: 80539

contact info
Titolo: Prof.
Nome: Norbert
Cognome: Mueller
Email: send email
Telefono: +49 89 5160 3397
Fax: +49 89 5160 4548

DE (MUENCHEN) participant 400˙509.00
5 Concentris Research Management GmbH DE participant 360˙000.00
6    TECHNISCHE UNIVERSITAET DRESDEN

 Organization address address: HELMHOLTZSTRASSE 10
city: DRESDEN
postcode: 1069

contact info
Titolo: Mr.
Nome: Carsten
Cognome: Glück
Email: send email
Telefono: 4935150000000
Fax: 4935150000000

DE (DRESDEN) participant 303˙394.00
7    UNIVERSITA DEGLI STUDI DI ROMA LA SAPIENZA

 Organization address address: Piazzale Aldo Moro 5
city: ROMA
postcode: 185

contact info
Titolo: Dr.
Nome: Francesco
Cognome: Cardona
Email: send email
Telefono: +39 06 44712288
Fax: +39 06 44712229

IT (ROMA) participant 298˙442.00
8    QUEEN MARY UNIVERSITY OF LONDON

 Organization address address: 327 MILE END ROAD
city: LONDON
postcode: E1 4NS

contact info
Titolo: Prof.
Nome: Gavin
Cognome: Giovannoni
Email: send email
Telefono: +44 20 7377 7472

UK (LONDON) participant 264˙928.00
9    UNIVERSITA DEGLI STUDI DI BARI ALDO MORO

 Organization address address: Piazza Umberto I 1
city: BARI
postcode: 70121

contact info
Titolo: Dr.
Nome: Maura
Cognome: Buttiglione
Email: send email
Telefono: +39 0 80 5478419
Fax: +39 0 80 5478417

IT (BARI) participant 241˙915.00
10    GLAXOSMITHKLINE VACCINES SRL

 Organization address address: Via Fiorentina 1
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: Francesco
Cognome: Gulli
Email: send email
Telefono: +39 0577 243390
Fax: +39 0577 243085

IT (SIENA) participant 209˙200.00
11    PROIMMUNE LTD

 Organization address address: ROBERT ROBINSON AVENUE THE MAGDALEN
city: OXFORD
postcode: OX4 4GA

contact info
Titolo: Dr.
Nome: Nikolai
Cognome: Schwabe
Email: send email
Telefono: +44 870 042 7279
Fax: +44 870 712 0588

UK (OXFORD) participant 194˙760.00
12    GUYS AND ST THOMAS' NHS FOUNDATIONTRUST

 Organization address address: Westminster Bridge Road
city: London
postcode: SE1 7EH

contact info
Titolo: Mr.
Nome: Peter
Cognome: Allanson
Email: send email
Telefono: +44 2071887188

UK (London) participant 183˙950.00
13    CLALIT HEALTH SERVICES

 Organization address address: ARLOZOROV STREET 101
city: TEL AVIV
postcode: 62098

contact info
Titolo: Ms.
Nome: Keren
Cognome: Tochterman
Email: send email
Telefono: 97239253452
Fax: 97239194132

IL (TEL AVIV) participant 152˙000.00
14    Department of Health

 Organization address address: Quarry House, Quarry Hill
city: Leeds
postcode: LS2 7UE

contact info
Titolo: Dr.
Nome: Phil
Cognome: Luton
Email: send email
Telefono: +44 1980 612725
Fax: +44 1980 612241

UK (Leeds) participant 148˙603.00
15    UNIVERSITY COLLEGE LONDON

 Organization address address: GOWER STREET
city: LONDON
postcode: WC1E 6BT

contact info
Titolo: Ms.
Nome: Greta
Cognome: Borg-Carbott
Email: send email
Telefono: +44 2031083033
Fax: +44 20 78132849

UK (LONDON) participant 144˙442.00
16    Advanced Practical Diagnostics

 Organization address address: Hertoginstraat 82
city: Turnhout
postcode: 2300

contact info
Titolo: Dr.
Nome: Aye Mu
Cognome: Myint
Email: send email
Telefono: 3214453599

BE (Turnhout) participant 144˙360.00
17    MEDIZINISCHE HOCHSCHULE HANNOVER

 Organization address address: Carl-Neuberg-Strasse 1
city: HANNOVER
postcode: 30625

contact info
Titolo: Mr.
Nome: Frank
Cognome: Dittrich
Email: send email
Telefono: +49 511 532 5343

DE (HANNOVER) participant 133˙800.00
18    REGION HOVEDSTADEN

 Organization address address: KONGENS VAENGE 2
city: HILLEROD
postcode: 3400

contact info
Titolo: Ms.
Nome: Pernille
Cognome: Rosling
Email: send email
Telefono: +45 38641003
Fax: +45 38641001

DK (HILLEROD) participant 121˙400.00
19    UNIVERSITA DEGLI STUDI DI CATANIA

 Organization address address: PIAZZA UNIVERSITA 2
city: CATANIA
postcode: 95131

contact info
Titolo: Dr.
Nome: Francesco
Cognome: Murabito
Email: send email
Telefono: +39 095 3782401
Fax: +39 095 3782779

IT (CATANIA) participant 113˙975.00
20    VADASKERT ALAPITVANY A GYERMEKEK LELKI EGESZSEGEERT

 Organization address address: HUVOSVOLGYI UT 116
city: BUDAPEST
postcode: 1021

contact info
Titolo: Dr.
Nome: Zsanett
Cognome: Tárnok
Email: send email
Telefono: 36703708429
Fax: 3613921436

HU (BUDAPEST) participant 111˙400.00
21    FUNDACIO PRIVADA CLINIC PER A LA RECERCA BIOMEDICA

 Organization address address: CARRER ROSSELLO 149-153
city: BARCELONA
postcode: 8029

contact info
Titolo: Ms.
Nome: Pastora
Cognome: Martinez Samper
Email: send email
Telefono: 34932275707
Fax: 34932279205

ES (BARCELONA) participant 101˙400.00
22    UNIVERSITAET ZU LUEBECK

 Organization address address: RATZEBURGER ALLEE 160
city: LUEBECK
postcode: 23538

contact info
Titolo: Mrs.
Nome: Gabriele
Cognome: Kipke
Email: send email
Telefono: 494515000000
Fax: 494515000000

DE (LUEBECK) participant 89˙800.00
23    AZIENDA SANITARIA LOCALE BARI

 Organization address address: LUNGOMARE STARITA 6
city: BARI
postcode: 70123

contact info
Titolo: Dr.
Nome: Nicola
Cognome: Pansini
Email: send email
Telefono: +39 080 5842568
Fax: +39 080 5842563

IT (BARI) participant 83˙400.00
24    Servicio Andaluz de Salud

 Organization address address: AVENIDA DE LA CONSTITUCION 18
city: SEVILLA
postcode: 41071

contact info
Titolo: Ms.
Nome: Sophie
Cognome: Monteau
Email: send email
Telefono: +34 671 597 572
Fax: +34 955 013 292

ES (SEVILLA) participant 75˙400.00
25    UNIVERSITAET ZUERICH

 Organization address address: Raemistrasse 71
city: ZURICH
postcode: 8006

contact info
Titolo: Prof.
Nome: Susanne
Cognome: Walitza
Email: send email
Telefono: +41 43 499 2730

CH (ZURICH) participant 73˙400.00
26    URWYLER ADRIAN - CYTOLAB

 Organization address address: RAIRING 66
city: DALLIKON
postcode: 8108

contact info
Titolo: Mr.
Nome: Adrian
Cognome: Urwyler
Email: send email
Telefono: +41 078 612 61 39
Fax: +41 43 931 02 44

CH (DALLIKON) participant 72˙000.00
27    Academisch Medisch Centrum bij de Universiteit van Amsterdam

 Organization address address: MEIBERGDREEF 9
city: AMSTERDAM
postcode: 1105AZ

contact info
Titolo: Mrs.
Nome: Eugenie
Cognome: Quartier
Email: send email
Telefono: 31205666188

NL (AMSTERDAM) participant 43˙275.00
28    HEALTH PROTECTION AGENCY HPA

 Organization address address: Central Office - 7th Floor, Holborn Gate - High Holborn 330
city: LONDON
postcode: WC1V 7PP

contact info
Titolo: Dr.
Nome: Philip
Cognome: Luton
Email: send email
Telefono: +44 1980612725
Fax: +44 1980612241

UK (LONDON) participant 0.00
29    THE UNIVERSITY OF BIRMINGHAM

 Organization address address: Edgbaston
city: BIRMINGHAM
postcode: B15 2TT

contact info
Titolo: Ms.
Nome: May
Cognome: Chung
Email: send email
Telefono: 441214000000

UK (BIRMINGHAM) participant 0.00
30    UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF

 Organization address address: Martinistrasse 52
city: HAMBURG
postcode: 20246

contact info
Titolo: Prof.
Nome: Alexander
Cognome: Münchau
Email: send email
Telefono: +49 40 7410 50134
Fax: +49 40 7410 40093

DE (HAMBURG) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

infections    gas    onset    clinical    risk    emtics    environmental    genetic    mechanisms    cohort    association    obsessive    strategy    streptococcus    tic    compulsive    treatment    comorbid    susceptibility    immunological    disorders   

 Obiettivo del progetto (Objective)

'This project will undertake pre-clinical and cohort studies that address susceptibility factors for paediatric and adolescent tic disorders, with a particular focus on comorbid obsessive-compulsive symptomatology, from clinical, epidemiological, genetic, microbiological and immunological angles. EMTICS aims to elucidate the complex aetiology of the onset and clinical course of chronic tic disorders and associated obsessive-compulsive symptoms, through disentangling the interplay between environmental factors and genetic background; translate research findings into clinical applications by developing disease prediction models and investigation of a treatment strategy; and will establish a Pan-European infrastructure for the study of tic disorders. We hypothesise that the onset and/or exacerbation of tic and comorbid obsessive-compulsive disorders is associated with increased preceding occurrence of Group A beta-haemolytic Streptococcus (GAS) infections of specific molecular subtypes, and that this association is based on genetic susceptibility factors and mediated through immunological mechanisms related to psychosocial stress and immunological factors in host and GAS strains. Large-scale cohort studies will involve affected patients and at-risk first-degree relatives within an integrated, multidisciplinary research strategy. Treatment effects of active surveillance and standardized antibiotic treatment of GAS colonisation, thus addressing one of the main environmental factors involved (GAS infections) will be evaluated. Our approach will result in the identification of genetic and environmental susceptibility factors and will greatly contribute to a better understanding of the underlying mechanisms of tic disorders, with a focus on elucidating the role of autoimmunity. Our consortium brings together the highest expertise in the field of tic disorders across Europe in academia and industry, including a number of SMEs and a professional management company.'

Introduzione (Teaser)

The EMTICS study is investigating the association between Streptococcus infection and tic disorders. The findings will shed light onto the pathogenesis of tic disorders and determine the genetic and environmental risk factors.

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