TRANS-INT

New Oral Nanomedicines: Transporting Therapeutic Macromolecules across the Intestinal Barrier

 Coordinatore UNIVERSIDADE DE SANTIAGO DE COMPOSTELA 

 Organization address address: "PAZO DE SAN XEROME, PRAZA DO OBRADOIRO S/N"
city: SANTIAGO DE COMPOSTELA
postcode: 15782

contact info
Titolo: Mr.
Nome: Martin
Cognome: Cacheiro Martinez
Email: send email
Telefono: +34 881 816233
Fax: +34 881 816263

 Nazionalità Coordinatore Spain [ES]
 Sito del progetto http://www.trans-int.eu
 Totale costo 10˙762˙810 €
 EC contributo 8˙000˙000 €
 Programma FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
 Code Call FP7-NMP-2011-LARGE-5
 Funding Scheme CP-IP
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-05-01   -   2017-04-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSIDADE DE SANTIAGO DE COMPOSTELA

 Organization address address: "PAZO DE SAN XEROME, PRAZA DO OBRADOIRO S/N"
city: SANTIAGO DE COMPOSTELA
postcode: 15782

contact info
Titolo: Mr.
Nome: Martin
Cognome: Cacheiro Martinez
Email: send email
Telefono: +34 881 816233
Fax: +34 881 816263

ES (SANTIAGO DE COMPOSTELA) coordinator 1˙878˙078.00
2    UNIVERSITY COLLEGE LONDON

 Organization address address: GOWER STREET
city: LONDON
postcode: WC1E 6BT

contact info
Titolo: Ms.
Nome: Greta
Cognome: Borg-Carbott
Email: send email
Telefono: +44 2031083033
Fax: +44 20 78132849

UK (LONDON) participant 699˙576.00
3    SANOFI-AVENTIS RECHERCHE & DEVELOPPEMENT

 Organization address address: Pierre Brossolette 1
city: Chilly Mazarin
postcode: 91380

contact info
Titolo: Dr.
Nome: Denis
Cognome: Croisat
Email: send email
Telefono: +33 1 58 93 81 40

FR (Chilly Mazarin) participant 616˙154.00
4    UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

 Organization address address: BELFIELD
city: DUBLIN
postcode: 4

contact info
Titolo: Mr.
Nome: Donal
Cognome: Doolan
Email: send email
Telefono: +3531 7161656

IE (DUBLIN) participant 587˙800.00
5    UNIVERSITE D'ANGERS

 Organization address address: Rue de Rennes 40
city: ANGERS
postcode: 49035

contact info
Titolo: Prof.
Nome: Jean-Pierre
Cognome: Benoit
Email: send email
Telefono: +33 2 44 68 85 45
Fax: +33 2 44 68 85 46

FR (ANGERS) participant 528˙598.00
6    UNIVERSITE CATHOLIQUE DE LOUVAIN

 Organization address address: Place De L'Universite 1
city: LOUVAIN LA NEUVE
postcode: 1348

contact info
Titolo: Prof.
Nome: Véronique
Cognome: Préat
Email: send email
Telefono: +32 2 764 73 09
Fax: +32 2 764 73 98

BE (LOUVAIN LA NEUVE) participant 506˙920.00
7    UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK

 Organization address address: Western Road
city: CORK
postcode: -

contact info
Titolo: Dr.
Nome: David
Cognome: O'connell
Email: send email
Telefono: 353214000000

IE (CORK) participant 459˙100.00
8    MEDIZINISCHE HOCHSCHULE HANNOVER

 Organization address address: Carl-Neuberg-Strasse 1
city: HANNOVER
postcode: 30625

contact info
Titolo: Mr.
Nome: Frank
Cognome: Dittrich
Email: send email
Telefono: +49 511 532 5343

DE (HANNOVER) participant 434˙880.00
9    UPPSALA UNIVERSITET

 Organization address address: SANKT OLOFSGATAN 10 B
city: UPPSALA
postcode: 751 05

contact info
Titolo: Ms.
Nome: Eva
Cognome: Nises Ahlgren
Email: send email
Telefono: +46 18 4714472
Fax: +46 18 4714223

SE (UPPSALA) participant 391˙300.00
10    SIGMOID PHARMA LIMITED

 Organization address address: THE INVENT CENTRE, DUBLIN CITY UNIVERSITY
city: DUBLIN
postcode: 9

contact info
Titolo: Dr.
Nome: Ivan S
Cognome: Coulter
Email: send email
Telefono: +353 1 7007511

IE (DUBLIN) participant 390˙900.00
11    SEROSCIENCE KUTATO FEJLESZTO ES KERESKEDELMI KORLATOLT FELELOSSEGU TARSASAG

 Organization address address: LORANT UTCA 10 B EP FSZT 2
city: BUDAPEST
postcode: 1125

contact info
Titolo: Mr.
Nome: Janos
Cognome: Csukás
Email: send email
Telefono: +36 208259690

HU (BUDAPEST) participant 346˙320.00
12    FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)

 Organization address address: CARRER BALDIRI REIXAC 10-12 PARC SCIENTIFIC DE BARCELONA
city: BARCELONA
postcode: 8028

contact info
Titolo: Mr.
Nome: Alexandre
Cognome: Puerto Valdivieso
Email: send email
Telefono: 34934039810
Fax: 34934037114

ES (BARCELONA) participant 302˙040.00
13    ISTITUTO ONCOLOGICO VENETO

 Organization address address: VIA GATTAMELAYA 64
city: PADOVA
postcode: 35128

contact info
Titolo: Ms.
Nome: Manuela
Cognome: Mtanis
Email: send email
Telefono: +39 0498215878
Fax: +39 0498215646

IT (PADOVA) participant 301˙400.00
14    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

 Organization address address: RUE LEBLANC 25
city: PARIS 15
postcode: 75015

contact info
Titolo: Dr.
Nome: Aloïse
Cognome: Mabondzo
Email: send email
Telefono: +33 1 69 08 13 21
Fax: +33 1 69 08 59 07

FR (PARIS 15) participant 296˙894.00
15    VENETO NANOTECH SCPA

 Organization address address: VIA SAN CRISPINO 106
city: PADOVA
postcode: 35129

contact info
Titolo: Ms.
Nome: Roberta
Cognome: Mitidieri
Email: send email
Telefono: +39 0497705500
Fax: +39 0497705555

IT (PADOVA) participant 260˙040.00
16    ADVANCELL ADVANCED IN VITRO CELL TECHNOLOGIES S.A

 Organization address address: CALLE BALDARI I REIXACH 10
city: Barcelona
postcode: 8028

contact info
Titolo: Dr.
Nome: Vila Pena
Cognome: Ana Isabel
Email: send email
Telefono: +34 881815573
Fax: +34 881815566

ES (Barcelona) participant 0.00
17    F. HOFFMANN-LA ROCHE AG

 Organization address address: GRENZACHERSTRASSE 124
city: BASEL
postcode: 4070

contact info
Titolo: Dr.
Nome: Barbara
Cognome: Lueckel
Email: send email
Telefono: 41616888160

CH (BASEL) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

criteria    efficient    nanocarrier    int    trans    least    impact    drug    nanocarriers    perspective    diseases    nanomedicines    oral    therapies   

 Obiettivo del progetto (Objective)

'Despite the increasing number of macromolecules with potential impact in the treatment of devastating systemic diseases, these therapies have failed to deliver on their expectations because they cannot be administered in the fashion which is most cost efficient and has the highest patient compliance: the oral route. The availability of an oral form of administration could lead to a great improvement of classical therapies and it would also make a high number of new therapies feasible. To make this happen, the final objective of Trans-INT is to design nanocarriers specifically adapted to deal with the gastrointestinal ecosystem and use them for the development of new oral nanomedicines for diseases with high socioeconomic impact (i.e. metabolic diseases, pain medication).

The concept behind TRANS-INT is the rational design of oral nanomedicines based on safety, mechanistic, bioengineering (multifunctional nanocarriers: high payload, drug protection, efficient drug transport, controlled release) and pharmaceutical technology criteria (scalable technology and stability). The project will start with nanocarrier platforms on which the partners have IPR and freedom to operate: nanocapsules, nanoparticles, micelles made of combinations of lipids, polypeptides and polysaccharides, continue with the optimization and redefinition of selected nanocarriers. It is expected to end with (i) at least one oral nanocarrier prototype with a comprehensive GLP-tox package, which could be applied for the delivery of a high number of peptide molecules, (ii) at least one nanomedicine fulfilling target product profile criteria, with a comprehensive preclinical evaluation package, (iii) substantial integrative knowledge on the feasibility and potential of oral nanocarriers and nanopharmaceuticals. TRANS-INT is expected to have a great impact no only from the new therapies/patients perspective but also from the innovation and EU industrial development perspective.'

Altri progetti dello stesso programma (FP7-NMP)

NANOSOLUTIONS (2013)

Biological Foundation for the Safety Classification of Engineered Nanomaterials (ENM): Systems Biology Approaches to Understand Interactions of ENM with Living Organisms and the Environment

Read More  

A-FOOTPRINT (2009)

Ankle and Foot Orthotic Personalisation via Rapid Manufacturing

Read More  

CUVITO (2010)

"Nano-structured copper coatings, based on Vitolane technology, for antimicrobial applications"

Read More