PHARMASEA

Increasing Value and Flow in the Marine Biodiscovery Pipeline

 Coordinatore KATHOLIEKE UNIVERSITEIT LEUVEN 

 Organization address address: Oude Markt 13
city: LEUVEN
postcode: 3000

contact info
Titolo: Ms.
Nome: Tine
Cognome: Heylen
Email: send email
Telefono: +32 16 326520
Fax: +32 16 326515

 Nazionalità Coordinatore Belgium [BE]
 Totale costo 13˙289˙395 €
 EC contributo 9˙465˙907 €
 Programma FP7-KBBE
Specific Programme "Cooperation": Food, Agriculture and Biotechnology
 Code Call FP7-KBBE-2012-6-singlestage
 Funding Scheme CP-TP
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-10-01   -   2016-09-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    KATHOLIEKE UNIVERSITEIT LEUVEN

 Organization address address: Oude Markt 13
city: LEUVEN
postcode: 3000

contact info
Titolo: Ms.
Nome: Tine
Cognome: Heylen
Email: send email
Telefono: +32 16 326520
Fax: +32 16 326515

BE (LEUVEN) coordinator 1˙119˙976.00
2    FUNDACION CENTRO DE EXCELENCIA EN INVESTIGACION DE MEDICAMENTOS INNOVADORES EN ANDALUCIA

 Organization address address: AVDA DEL CONOCIMIENTO 3
city: ARMILLA GRANADA
postcode: 18100

contact info
Titolo: Mr.
Nome: Diego
Cognome: Pozas
Email: send email
Telefono: +34 958993965

ES (ARMILLA GRANADA) participant 818˙294.00
3    THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN

 Organization address address: KING'S COLLEGE REGENT WALK
city: ABERDEEN
postcode: AB24 3FX

contact info
Titolo: Ms.
Nome: Kerry
Cognome: Kidd
Email: send email
Telefono: +44 1224 272663

UK (ABERDEEN) participant 753˙273.00
4    UNIVERSITETET I TROMSOE

 Organization address address: Hansine Hansens veg 14
city: TROMSO
postcode: 9037

contact info
Titolo: Dr.
Nome: Jeanette Hammer
Cognome: Andersen
Email: send email
Telefono: 4777649261

NO (TROMSO) participant 746˙667.00
5    SEALIFE PHARMA GMBH

 Organization address address: TECHNOPARK 1 GEB B EG
city: TULLN
postcode: 3430

contact info
Titolo: Dr.
Nome: Alexander
Cognome: Pretsch
Email: send email
Telefono: 436642000000
Fax: 4322730000000

AT (TULLN) participant 624˙815.00
6    UNIVERSIDADE DE SANTIAGO DE COMPOSTELA

 Organization address address: "PAZO DE SAN XEROME, PRAZA DO OBRADOIRO S/N"
city: SANTIAGO DE COMPOSTELA
postcode: 15782

contact info
Titolo: Mr.
Nome: Martin
Cognome: Cacheiro Martinez
Email: send email
Telefono: +34 881 816233
Fax: +34 881 816263

ES (SANTIAGO DE COMPOSTELA) participant 612˙176.00
7    ECOAST RESEARCH CENTRE OSTEND BVBA

 Organization address address: POLDERSTRAAT 3
city: DAMME
postcode: 8340

contact info
Titolo: Dr.
Nome: Thomas
Cognome: Vanagt
Email: send email
Telefono: +32 59 270 400

BE (DAMME) participant 524˙911.00
8    DANMARKS TEKNISKE UNIVERSITET

 Organization address address: Anker Engelundsvej 1, Building 101A
city: KONGENS LYNGBY
postcode: 2800

contact info
Titolo: Ms.
Nome: Kristina
Cognome: Holdgaard-Sørensen
Email: send email
Telefono: +45 25161403

DK (KONGENS LYNGBY) participant 442˙212.00
9    ADVANCED CHEMISTRY DEVELOPMENT UK LIMITED

 Organization address address: NEW STREET SQUARE 5
city: LONDON
postcode: EC4 3TW

contact info
Titolo: Mr.
Nome: Michael
Cognome: Partington
Email: send email
Telefono: +44 01344 668030
Fax: +44 01344 668230

UK (LONDON) participant 442˙090.00
10    CONSIGLIO NAZIONALE DELLE RICERCHE

 Organization address address: Piazzale Aldo Moro 7
city: ROMA
postcode: 185

contact info
Titolo: Dr.
Nome: Donatella
Cognome: De Pascale
Email: send email
Telefono: 390816000000
Fax: 390816000000

IT (ROMA) participant 429˙266.00
11    UNIVERSITY COLLEGE CORK, NATIONAL UNIVERSITY OF IRELAND, CORK

 Organization address address: Western Road
city: CORK
postcode: -

contact info
Titolo: Dr.
Nome: David
Cognome: O Connell
Email: send email
Telefono: +353 214903501
Fax: +353 214903506

IE (CORK) participant 418˙152.00
12    STAZIONE ZOOLOGICA ANTON DOHRN

 Organization address address: Villa Comunale
city: NAPOLI
postcode: 80121

contact info
Titolo: Dr.
Nome: Giosuè
Cognome: Zurzolo
Email: send email
Telefono: 390816000000

IT (NAPOLI) participant 409˙022.00
13    DEEP TEK LIMITED

 Organization address address: KILBURNS
city: NEWPORT ON TAY
postcode: DD6 8PL

contact info
Titolo: Mrs.
Nome: Moya
Cognome: Crawford
Email: send email
Telefono: +44 1382 330240

UK (NEWPORT ON TAY) participant 389˙286.00
14    C-LECTA GMBH

 Organization address address: Deutscher Platz 5b
city: Leipzig
postcode: 4103

contact info
Titolo: Ms.
Nome: Heike
Cognome: Kutschke
Email: send email
Telefono: +49 341 35521415
Fax: +49 341 35521433

DE (Leipzig) participant 302˙947.00
15    BIOCOM

 Organization address address: LUTZOWSTRASSE 33-36
city: BERLIN
postcode: 10785

contact info
Titolo: Dr.
Nome: Boris
Cognome: Mannhardt
Email: send email
Telefono: +49 30 26492161
Fax: +49 30 26492111

DE (BERLIN) participant 268˙815.00
16    THE ROYAL SOCIETY OF CHEMISTRY

 Organization address address: Milton Road - Thomas Graham House - Science Park
city: CAMBRIDGE
postcode: CB4 0WF

contact info
Titolo: Mr.
Nome: Richard
Cognome: Kidd
Email: send email
Telefono: +44 1223 432344

UK (CAMBRIDGE) participant 245˙039.00
17    "Institute of Microbiology, Chinese Academy of Sciences"

 Organization address address: West Beichen Road 1
city: Beijing
postcode: 100101

contact info
Titolo: Ms.
Nome: Shaofeng
Cognome: Li
Email: send email
Telefono: +86 13810828692

CN (Beijing) participant 148˙508.00
18    ASOCIACION INSTITUTO NACIONAL DE BIODIVERSIDAD

 Organization address address: "400 M. NORTE, 300 M. OESTE DEL CEMENTERIO"
city: SANTO DOMINGO DE HEREDIA
postcode: 3100

contact info
Titolo: Ms.
Nome: Nora
Cognome: Martin
Email: send email
Telefono: +506 2507 8246

CR (SANTO DOMINGO DE HEREDIA) participant 148˙508.00
19    Instituto de Dinamica Celular y Biotecnologia

 Organization address address: CALLE BEAUCHEF 850
city: SANTIAGO
postcode: 8370448

contact info
Titolo: Prof.
Nome: Juan
Cognome: Asenjo
Email: send email
Telefono: +56 2 978 4723
Fax: +56 2 699 1084

CL (SANTIAGO) participant 148˙508.00
20    UNIVERSITY OF THE WESTERN CAPE

 Organization address address: MODDERDAMM ROAD
city: BELLVILLE
postcode: 7535

contact info
Titolo: Prof.
Nome: Marla
Cognome: Tuffin
Email: send email
Telefono: 27219592083

ZA (BELLVILLE) participant 148˙508.00
21    WUHAN UNIVERSITY

 Organization address address: LUOJIA HILL
city: WUHAN
postcode: 430072

contact info
Titolo: Prof.
Nome: Zixin
Cognome: Deng
Email: send email
Telefono: +86 2768755417
Fax: +86 2768752442

CN (WUHAN) participant 148˙508.00
22    BIOBRIDGE LIMITED

 Organization address address: ST. BARNABAS ROAD 45
city: CAMBRIDGE
postcode: CB1 2BX

contact info
Titolo: Mr.
Nome: Meredith
Cognome: Lloyd-Evans
Email: send email
Telefono: +44 1223 566850

UK (CAMBRIDGE) participant 116˙699.00
23    UNION INTERNATIONALE POUR LA CONSERVATION DE LA NATURE ET DE SES RESSOURCES

 Organization address address: RUE MAUVERNEY 28
city: GLAND
postcode: 1196

contact info
Titolo: Mr.
Nome: Thomas
Cognome: Greiber
Email: send email
Telefono: +49 228 2692 230

CH (GLAND) participant 59˙727.00
24    AQUAPHARM BIODISCOVERY LIMITED

 Organization address address: Glenfinlas Street
city: EDINBURGH
postcode: EH3 6AQ

contact info
Titolo: Prof.
Nome: Andrew
Cognome: Mearns Spragg
Email: send email
Telefono: +44 131 5263193

UK (EDINBURGH) participant 0.00
25    UNIVERSITY OF WAIKATO

 Organization address address: HILLCREST ROAD BLOCK B
city: HAMILTON
postcode: 2020

contact info
Titolo: Ms.
Nome: Jan
Cognome: Bates
Email: send email
Telefono: +64 7 838 4349

NZ (HAMILTON) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

diseases    inflammation    biological    environments    strain    strains    bottlenecks    bioresources    flow    biodiscovery    infection    solutions    thereby    evaluation    pharmasea    collections    deep    benefits    pre    extreme    environment    central    microorganisms    pipeline    larger    compounds    despite    interdisciplinary    organisms    nutrition    policy    clinical    nervous    marine    data    industry    sectors    habitats    genetic    microbial    structure    ocean   

 Obiettivo del progetto (Objective)

'The PharmaSea project focuses on obstacles in marine biodiscovery research, development and commercialization and brings together a broad interdisciplinary team of academic and industry researchers and specialists to address and overcome these. The partners are ideally placed to demonstrate how to widen the bottlenecks and increase the flow of ideas and products derived from the marine microbiome towards a greater number of successes in a larger number of application areas. Despite the tremendous potential of marine biodiscovery, exploitation, particularly at a commercial scale, has been hampered by a number of constraints. These relate to access (physical and legal), genetics of the organisms, compound isolation, structure elucidation, early reliable validation of biological activity and best mechanisms of flow-through into exploitation. PharmaSea will solve these chronic bottlenecks by developing essential actions beyond the state of the art and linking them with best practice and appropriate pragmatic approaches. The robust pipeline structure established within PharmaSea will process a wide genetic basis including marine microbial strain collections held by partners and new strain collections from extreme environments (deep, cold and hot vent habitats) to produce new products with desirable characteristics for development by the SME partners in three accessible market sectors, health (infection, inflammation, CNS diseases), personal care and nutrition. The global aim of PharmaSea is to produce two compounds at larger scale and advance them to pre-clinical evaluation. To address relevant challenges in marine biodiscovery related to policy and legal issues, PharmaSea will bring together practitioners, legal experts, policy advisors/makers and other stakeholders, focusing on the feasibility of harmonising, aligning and complementing current legal frameworks with recommendations and ready to use solutions tailored to marine biodiscovery.'

Introduzione (Teaser)

The world's oceans are home to more living organisms, especially microorganisms, than any other environment on the planet. However, successful exploitation of this exceptional resource has been limited, despite its enormous potential for harvesting unique biological compounds with benefits for all of humanity.

Descrizione progetto (Article)

The purpose of the project 'Increasing value and flow in the marine biodiscovery pipeline' (http://www.pharma-sea.eu/ (PHARMASEA)) is to discover new marine bacteria and novel compounds. In addition, the consortium will improve the effectiveness of the biodiscovery pipeline, thereby making bioresources attractive to industry.

Project partners will achieve their aim by processing genetic material from in-house collections of microbial strains, while seeking out new strains from extreme marine environments. These will be used to develop new products for the pharmaceutical, food and nutrition, and cosmetic sectors. The main disease areas to be addressed are microbial infection, diseases of the central nervous system and inflammation.

By sampling some of the deepest parts of the ocean floor, PHARMASEA hopes to utilise microorganisms that are new to science. Deep ocean trenches are 'islands of diversity' with a unique chemistry and where evolution may have developed differently. Because so little of this extreme environment has been explored, PHARMASEA is breaking new ground.

The final goal of this exciting initiative is to produce two compounds from newly discovered microorganisms on a large scale. These compounds will be taken forward to pre-clinical evaluation for treating infection or diseases of the central nervous system. Other outputs will include a validated model biodiscovery pipeline, new chemometric tools, data mining techniques and data sets.

Furthermore, PHARMASEA will develop solutions to improving access to marine bioresources in different habitats and jurisdictions, and equitable sharing of the benefits from their exploitation. A toolbox will also be created to navigate legal aspects in order to simplify and speed up the marine biodiscovery process.

PHARMASEA is not just expected to have a major impact on scientific progress, it will also influence policy and enhance economic performance. It will also strengthen the competiveness of the European Research Area (ERA) by increasing technological know-how through interdisciplinary and international cooperation, thereby contributing to Europe's knowledge-based economy.

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