ASSURE

Adapting Breast Cancer Screening Strategy Using Personalised Risk Estimation

 Coordinatore STICHTING KATHOLIEKE UNIVERSITEIT 

 Organization address address: GEERT GROOTEPLEIN NOORD 9
city: NIJMEGEN
postcode: 6525 EZ

contact info
Titolo: Prof.
Nome: Nico
Cognome: Karssemeijer
Email: send email
Telefono: +31 24 3614548

 Nazionalità Coordinatore Netherlands [NL]
 Sito del progetto http://www.assure-project.eu
 Totale costo 7˙235˙026 €
 EC contributo 5˙608˙543 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2012-INNOVATION-1
 Funding Scheme CP-FP
 Anno di inizio 2012
 Periodo (anno-mese-giorno) 2012-12-01   -   2015-11-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    STICHTING KATHOLIEKE UNIVERSITEIT

 Organization address address: GEERT GROOTEPLEIN NOORD 9
city: NIJMEGEN
postcode: 6525 EZ

contact info
Titolo: Prof.
Nome: Nico
Cognome: Karssemeijer
Email: send email
Telefono: +31 24 3614548

NL (NIJMEGEN) coordinator 1˙048˙127.20
2    MEVIS MEDICAL SOLUTIONS AG

 Organization address address: UNIVERSITAETSALLEE 29
city: BREMEN
postcode: 28359

contact info
Titolo: Mr.
Nome: Thomas
Cognome: Pross
Email: send email
Telefono: +49 421 22 49 578 30
Fax: +49 421 22 49 512

DE (BREMEN) participant 796˙125.60
3    BIOMEDIQ AS

 Organization address address: FRUEBJERGVEJ 3
city: KOBENHAVN
postcode: 2100

contact info
Titolo: Ms.
Nome: Camilla
Cognome: Jørgensen
Email: send email
Telefono: +45 30589643

DK (KOBENHAVN) participant 700˙086.80
4    THE UNIVERSITY OF MANCHESTER

 Organization address address: OXFORD ROAD
city: MANCHESTER
postcode: M13 9PL

contact info
Titolo: Dr.
Nome: Katherine
Cognome: Boylan
Email: send email
Telefono: +44 161 275 8796
Fax: +44 161 233 0397

UK (MANCHESTER) participant 687˙413.60
5    MATAKINA UK LIMITED

 Organization address address: WALNUT TREE CLOSE 1
city: ELY
postcode: CB6 2SQ

contact info
Titolo: Dr.
Nome: Ralph
Cognome: Highnam
Email: send email
Telefono: +44 1353 468 029
Fax: +44 1353 468 028

UK (ELY) participant 631˙680.75
6    FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V

 Organization address address: Hansastrasse 27C
city: MUENCHEN
postcode: 80686

contact info
Titolo: Mr.
Nome: Christoph
Cognome: Schulte
Email: send email
Telefono: +49 89 1205 2728
Fax: +49 89 1205 7534

DE (MUENCHEN) participant 566˙798.75
7    Medical Imaging Research Institute

 Organization address address: Vangerowstr. 18
city: Heidelberg
postcode: 69115

contact info
Titolo: Dr.
Nome: Johannes
Cognome: Gregori
Email: send email
Telefono: +49 6221 43338813

DE (Heidelberg) participant 404˙360.00
8    UNIVERSITAT DE GIRONA

 Organization address address: PLACA SANT DOMENEC 9 EDIFICI LES ALIGUES
city: GIRONA
postcode: 17071

contact info
Titolo: Dr.
Nome: Montserrat
Cognome: Estopà
Email: send email
Telefono: +34 972 41 8869

ES (GIRONA) participant 355˙290.40
9    UNIVERSITAIR MEDISCH CENTRUM UTRECHT

 Organization address address: HEIDELBERGLAAN 100
city: UTRECHT
postcode: 3584 CX

contact info
Titolo: Dr.
Nome: Carla H
Cognome: Van Gils
Email: send email
Telefono: +31 88 7553014

NL (UTRECHT) participant 263˙095.20
10    Institut Jules Bordet

 Organization address city: Brussels
postcode: 1000

contact info
Titolo: Ms.
Nome: Marielle
Cognome: Sautois
Email: send email
Telefono: 3225413214

BE (Brussels) participant 155˙565.20

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

mammograms    cancer    risk    strategies    density    effectiveness    imaging    benefit    breast    detection    women    mri    breasts    ultrasound    screening    personalised    dense    efficient    smes    model    protocols   

 Obiettivo del progetto (Objective)

'While early detection of breast cancer by screening appears effective, many women derive little or no benefit from screening, due to the way it is currently organized: as a one-size-fits all approach irrespective of personalised risk factors. It is known, however, that some women are at a much higher risk of getting the disease than others, and that mammography is unsuitable for cancer detection in women with dense breasts. The aim of this project is to develop personalised methods to tailor breast cancer screening to the individual needs of the woman. We will propose methods to stratify women at the highest risk to MRI; those with intermediate risk and/or dense breasts to follow-on ultrasound. A risk model will be developed that includes both breast cancer risk and the risk of missing cancers in mammograms. In this model, breast density plays a key role, as one of the largest known risk factors and the factor making mammograms ineffective. Two SMEs focusing on breast density are involved, where academic partners bring unique databases with over 80,000 screening mammograms and associated risk profiles. These are essential for model development, and subsequently for the development of products that benefit all women. Personalised screening is only economically feasible if it is based upon cost-effective strategies. While current methods in breast MRI imaging and breast ultrasound are promising, more efficient protocols must be developed to use these modalities routinely in screening. With leading SMEs and clinical partners, screening procedures will be optimized by developing automated image analysis tools to guide workflow and quality assurance. More efficient MRI protocols will be investigated to reduce time and cost, while the use of novel MRI imaging sequences without intravenous contrast will be explored. Cost-effectiveness of the stratification models will be assessed by combining the risk model with cost and effectiveness of alternative screening strategies.'

Altri progetti dello stesso programma (FP7-HEALTH)

EUROSARC (2011)

European Clinical trials in Rare Sarcomas within an integrated translational trial network

Read More  

COMBI-BIO (2012)

Development of COMBInatorial BIOmarkers for subclinical atherosclerosis

Read More  

PREPOBEDIA (2008)

NOVEL PREP1-DEPENDENT TRANSCRIPTIONAL NETWORKS IN THE CONTROL OF INSULIN SENSITIVITY

Read More