CORTICONIC

Computations and Organization of Retes Through the Interaction ofnComputational, Optical and Neurophysiological Investigations of the Cerebral cortex

 Coordinatore CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER 

 Organization address city: Barcelona
postcode: 8036

contact info
Titolo: Dr.
Nome: Pastora
Cognome: Martinez
Email: send email
Telefono: 34932275707
Fax: 34932279205

 Nazionalità Coordinatore Spain [ES]
 Totale costo 3˙085˙165 €
 EC contributo 2˙399˙000 €
 Programma FP7-ICT
Specific Programme "Cooperation": Information and communication technologies
 Code Call FP7-ICT-2011-9
 Funding Scheme CP
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-01-01   -   2015-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    CONSORCI INSTITUT D'INVESTIGACIONS BIOMEDIQUES AUGUST PI I SUNYER

 Organization address city: Barcelona
postcode: 8036

contact info
Titolo: Dr.
Nome: Pastora
Cognome: Martinez
Email: send email
Telefono: 34932275707
Fax: 34932279205

ES (Barcelona) coordinator 0.00
2    CONSIGLIO NAZIONALE DELLE RICERCHE

 Organization address address: PIAZZALE ALDO MORO
city: ROMA
postcode: 185

contact info
Titolo: Dr.
Nome: Corrado
Cognome: Spinella
Email: send email
Telefono: 390956000000
Fax: 390956000000

IT (ROMA) participant 0.00
3    ISTITUTO SUPERIORE DI SANITA

 Organization address address: Viale Regina Elena 299
city: ROMA
postcode: 161

contact info
Titolo: Dr.
Nome: ROSA MARIA
Cognome: MARTOCCIA
Email: send email
Telefono: +39 06 49902688
Fax: +39 06 49903007

IT (ROMA) participant 0.00
4    TECHNISCHE UNIVERSITAET MUENCHEN

 Organization address address: Arcisstrasse
city: MUENCHEN
postcode: 80333

contact info
Titolo: Ms.
Nome: Katrin
Cognome: Hörmann
Email: send email
Telefono: 498929000000
Fax: 498929000000

DE (MUENCHEN) participant 0.00
5    UNIVERSITA DEGLI STUDI DI MILANO

 Organization address address: Via Festa Del Perdono
city: MILANO
postcode: 20122

contact info
Titolo: Dr.
Nome: STEFANO
Cognome: NADOTTI
Email: send email
Telefono: +39 0250319638
Fax: +39 02 38200385

IT (MILANO) participant 0.00

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cortical    tissue    interfaces    computational    dynamic    brain    neural    computing    cortex    function   

 Obiettivo del progetto (Objective)

Corticonics, echoing electronics, consists of abstracting salient features of cortical organization for use in the simulation of the cortex executing higher level brain functions. Our final objective is to identify computational principles of the cerebral cortex underlying network dynamic patterns. In our long term vision, interfacing with the brain will take place: i) Towards the brain, delivering stimuli onto the nervous tissue to induce recovery, correct imbalances or to augment function and cognition, and ii) From the brain: to be able to operate machines by thinking. Both interfaces require a detailed understanding of brain function. Our project has a multilevel experimental approach, covering scales from the micro to the macro, combined with a theoretical/computational approach. We take slow oscillations observed during sleep or anaesthesia as a basic dynamic pattern constrained by features of the excitability distribution in the neural tissue. We aim to identify these features by analysing the generation and propagation of activity and its susceptibility to interference. Progressively we will wake up the cortex in order to identify the features that are critical in adding computational complexity to the system.nTo achieve this we start by developing novel recording tools to obtain detailed subcellular and large cortical area recordings while we will further develop electrical and targeted optogenetic stimulation for the spatiotemporal control of activity. Based on this mesoscopic and modular approach we will provide a computational equivalent of the properties of a macroscopic region of neural tissue described as an excitable medium, and carry out large scale simulations made possible by a cutting-edge distributed computing facility.nThe approach and technologies developed here will have long term implications for areas including brain-computer interfaces, brain repair, brain modelling and massive scale computing.

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