PRONIA

Personalised Prognostic Tools for Early Psychosis Management

Coordinatore	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN    more  Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 contact info Titolo: Dr. Nome: Nikolaos Cognome: Koutsouleris Email: send email Telefono: +49 8951605717 Fax: +49 8951603413
Nazionalità Coordinatore	Germany [DE]
Sito del progetto	http://www.pronia.eu
Totale costo	9˙242˙843 €
EC contributo	6˙000˙000 €
Programma	FP7-HEALTH Specific Programme "Cooperation": Health
Code Call	FP7-HEALTH-2013-INNOVATION-1
Funding Scheme	CP-FP
Anno di inizio	2013
Periodo (anno-mese-giorno)	2013-10-01   -   2018-09-30

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN  Organization address address: GESCHWISTER SCHOLL PLATZ 1 city: MUENCHEN postcode: 80539 contact info Titolo: Dr. Nome: Nikolaos Cognome: Koutsouleris Email: send email Telefono: +49 8951605717 Fax: +49 8951603413	DE (MUENCHEN)	coordinator	863˙015.00
2	DYNAMIC EVOLUTION GMBH  Organization address address: LICHTENBERGSTRASSE 8 city: GARCHING postcode: 85748 contact info Titolo: Mr. Nome: Michael Cognome: Jovicevic Email: send email Telefono: +49 89 31 888 501	DE (GARCHING)	participant	833˙220.00
3	THE UNIVERSITY OF BIRMINGHAM  Organization address address: Edgbaston city: BIRMINGHAM postcode: B15 2TT contact info Titolo: Ms. Nome: May Cognome: Chung Email: send email Telefono: 441214000000 Fax: 441214000000	UK (BIRMINGHAM)	participant	689˙755.00
4	TURUN YLIOPISTO  Organization address address: YLIOPISTONMAKI city: TURUN YLIOPISTO postcode: 20014 contact info Titolo: Dr. Nome: Mari Cognome: Riipinen Email: send email Telefono: +358 2 3336054 Fax: +358 2 3336363	FI (TURUN YLIOPISTO)	participant	681˙550.00
5	UNIVERSITAET BASEL  Organization address address: Petersplatz 1 city: BASEL postcode: 4003 contact info Titolo: Prof. Nome: Stefan Cognome: Borgwardt Email: send email Telefono: +41 612655119 Fax: +41 61 265 45 88	CH (BASEL)	participant	673˙298.00
6	KLINIKUM DER UNIVERSITAET ZU KOELN  Organization address address: Kerpener Strasse 62 city: KOELN postcode: 50937 contact info Titolo: Mrs. Nome: Petra Cognome: Schreiner-Kaub Email: send email Telefono: +49 22147898413 Fax: +49 2214781498413	DE (KOELN)	participant	650˙340.00
7	UNIVERSITA DEGLI STUDI DI UDINE  Organization address address: VIA PALLADIO 8 city: UDINE postcode: 33100 contact info Nome: Marina Cognome: Dorligh Email: send email Telefono: +39 0432494202	IT (UDINE)	participant	641˙953.00
8	GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG GAB O  Organization address address: Oskar-von-Miller-Ring 29 city: MUENCHEN postcode: 80333 contact info Titolo: Ms. Nome: Birgit Cognome: Fuchs Email: send email Telefono: +49 8928810414	DE (MUENCHEN)	participant	400˙000.00
9	General Electric Deutschland Holding GmbH  Organization address address: Martin-Behaim str. 10 city: Neu-Isenburg postcode: 63263 contact info Nome: Manuela Cognome: Abraham Email: send email Telefono: +49 89 5528 3208	DE (Neu-Isenburg)	participant	293˙279.00
10	GE HEALTHCARE GMBH - GEHC  Organization address address: BEETHOVENSTRASSE 239 city: SOLINGEN postcode: 42655 contact info Titolo: Dr. Nome: Katrin Cognome: Herrmann Email: send email Telefono: +49 89 96281 152	DE (SOLINGEN)	participant	273˙590.00
11	UNIVERSITY OF MELBOURNE  Organization address address: PARKVILLEOFFICE OF THE VICE CHANCELLOR city: MELBOURNE postcode: 3010 contact info Titolo: Ms. Nome: Melinda Cognome: Heron Email: send email Telefono: +61 383442052 Fax: +613 9347 6730	AU (MELBOURNE)	participant	0.00

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 Obiettivo del progetto (Objective)

'Affective and non-affective psychoses have a major negative impact on human society. They account for 6.3% of the global burden of disease and cost €207 billion per year in Europe alone, making them the most expensive brain-related disorders and even more expensive than cardiovascular diseases. This socioeconomic burden is largely caused by two core disease features: onset in adolescence and early adulthood and long-term disabling disease courses. Both factors lead to enduring social and vocational exclusion and contribute to 8-20 times higher suicide rates in affected patients. Reliable and accessible prognostic tools will alleviate this burden by enabling individualised risk prediction, thus facilitating the targeted prevention of psychoses. Thus, we will first use routine brain imaging and complementary data to optimise our candidate biomarkers for the prediction and staging of psychoses and generate a prognostic system that generalises well across mental health services. Secondly, we will implement new multi-modal risk quantification tools to predict mental health-related disability in young help-seekers. The fusion of these tools with clinical knowledge will produce cybernetic prognostic services that accurately identify help-seekers at the highest risk of psychosis, poor functioning and suicide-related mortality. During this project we will secure our intellectual property rights and transform into a European company to commercially exploit these prognostic services through internet-based telemedicine applications. This will provide psychosis risk profiling tools to diverse target groups in the healthcare markets, including care-givers, the pharmaceutical industry and research institutions. By disseminating objective risk quantification, these products will provide firm diagnostic grounds for preventive therapy, improving outcomes and reducing costs. Thus, they will offer a unique selling proposition to the mental health sectors in Europe and beyond.'