CELLULOSOMEPLUS

Boosting Lignocellulose Biomass Deconstruction with Designer Cellulosomes for Industrial Applications

 Coordinatore AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS 

 Organization address address: CALLE SERRANO 117
city: MADRID
postcode: 28006

contact info
Titolo: Ms.
Nome: Ana Maria
Cognome: De La Fuente
Email: send email
Telefono: 34915681709

 Nazionalità Coordinatore Spain [ES]
 Totale costo 5˙284˙901 €
 EC contributo 3˙997˙019 €
 Programma FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
 Code Call FP7-NMP-2013-SMALL-7
 Funding Scheme CP-FP
 Anno di inizio 2013
 Periodo (anno-mese-giorno) 2013-11-01   -   2017-10-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS

 Organization address address: CALLE SERRANO 117
city: MADRID
postcode: 28006

contact info
Titolo: Ms.
Nome: Ana Maria
Cognome: De La Fuente
Email: send email
Telefono: 34915681709

ES (MADRID) coordinator 1˙178˙477.00
2    WEIZMANN INSTITUTE OF SCIENCE

 Organization address address: HERZL STREET 234
city: REHOVOT
postcode: 7610001

contact info
Titolo: Ms.
Nome: Gaby
Cognome: Bernstein
Email: send email
Telefono: +972 8 934 6728
Fax: +972 8 934 4165

IL (REHOVOT) participant 509˙540.00
3    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

 Organization address address: Rue Michel -Ange 3
city: PARIS
postcode: 75794

contact info
Titolo: Ms.
Nome: Emilie
Cognome: Floch
Email: send email
Telefono: +33 2 99286824

FR (PARIS) participant 454˙266.00
4    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN

 Organization address address: GESCHWISTER SCHOLL PLATZ 1
city: MUENCHEN
postcode: 80539

contact info
Titolo: Prof.
Nome: Hermann E
Cognome: Gaub
Email: send email
Telefono: +49 08921803172
Fax: +49 0892180205

DE (MUENCHEN) participant 411˙498.80
5    DESIGNER ENERGY LTD

 Organization address address: BERGMAN 2
city: REHOVOT
postcode: 76705

contact info
Titolo: Mr.
Nome: Alon
Cognome: Karpol
Email: send email
Telefono: +972 89366612
Fax: +972 89366614

IL (REHOVOT) participant 372˙896.40
6    INSTYTUT FIZYKI POLSKIEJ AKADEMII NAUK

 Organization address address: AL LOTNIKOW 32/46
city: WARSZAWA
postcode: 02 668

contact info
Titolo: Prof.
Nome: Marek
Cognome: Cieplak
Email: send email
Telefono: +48 228436601
Fax: +48 228475223

PL (WARSZAWA) participant 369˙200.00
7    UNIVERSITY OF LIMERICK

 Organization address address: NATIONAL TECHNOLOGICAL PARK, PLASSEY
city: LIMERICK
postcode: -

contact info
Titolo: Ms.
Nome: Sandra
Cognome: Hammersley
Email: send email
Telefono: +353 61 234310
Fax: +353 61 233642

IE (LIMERICK) participant 347˙479.20
8    ABENGOA BIOENERGIA NUEVAS TECNOLOGIAS SA

 Organization address address: AVENIDA DE LA BUHAIRA 2
city: SEVILLA
postcode: 41018

contact info
Titolo: Ms.
Nome: Carmen
Cognome: Millán
Email: send email
Telefono: +34 954978865
Fax: +34 955413373

ES (SEVILLA) participant 190˙125.60
9    BIOPOLIS SL

 Organization address address: CALLE CATEDRATICO AGUSTIN ESCARDINO 9
city: PATERNA VALENCIA
postcode: 46980

contact info
Titolo: Ms.
Nome: Iryna
Cognome: Sukhotska
Email: send email
Telefono: +34 963160299
Fax: +34 963160367

ES (PATERNA VALENCIA) participant 163˙536.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

cellulosomes    materials    municipal    enzymatic    biomass    biofuels    natural    proteinaceous    waste    cellulosomal    components    optimized    selectivity   

 Obiettivo del progetto (Objective)

'The major bottleneck for plant biomass processing is fiber saccharification: the conversion of cell wall lignocellulosic biomass into fermentable sugars (en route to production of value-added chemicals like second generation biofuels). Some microbes enhance this step by using natural self-assembling proteinaceous nanocatalists known as cellulosomes. CellulosomePlus targets rational design of optimized cellulosomes to overcome this problem.This would allow efficient production of biofuels from low-value raw materials like inedible parts of plants and industrial residues (which are all renewable, sustainable and inexpensive). First we propose to characterize the physicochemical and structural properties (including mechanostability) as well as interactions of enzymes and scaffolds from natural cellulosomes and non-cellulosomal components. In parallel, we will characterize a suitable residual substrate from municipal waste (organic fraction of municipal solid waste) and develop improved assays to reliably follow cellulosomal enzymatic activity. The acquired knowledge will be complemented with rapid computational modelling at the atomic and supramolecular levels for testing and predictions. Experimental and theoretical knowledge will be then integrated to design improved cellulosomes (with high-selectivity, activity and cost-effectiveness). Further improvement will be obtained by iteration using high throughput screening of components. The improved cellulosomes generated through this innovative multidisciplinary approach represent a step towards green chemistry since they are biodegradable proteinaceous materials and therefore by-products and/or wastes are minimized due to the high enzymatic selectivity. Finally, the production of the optimized cellulosomes (and the process involved) will be scaled up to preindustrial scale to demonstrate their viable commercial production. These results will be patented and a roadmap will be drawn up towards future standardization.'

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