SURE-ALISM

SUpeR REsolution Adaptive LIght Sheet Microscopy for high resolution volumetric imaging in turbid specimen

 Coordinatore UNIVERSIDAD CARLOS III DE MADRID 

 Organization address address: CALLE MADRID 126
city: GETAFE (MADRID)
postcode: 28903

contact info
Titolo: Ms.
Nome: Regina
Cognome: García Beato
Email: send email
Telefono: +34 916249931

 Nazionalità Coordinatore Spain [ES]
 Totale costo 173˙370 €
 EC contributo 173˙370 €
 Programma FP7-PEOPLE
Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013)
 Code Call FP7-PEOPLE-2013-IEF
 Funding Scheme MC-IEF
 Anno di inizio 2014
 Periodo (anno-mese-giorno) 2014-09-15   -   2016-09-14

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSIDAD CARLOS III DE MADRID

 Organization address address: CALLE MADRID 126
city: GETAFE (MADRID)
postcode: 28903

contact info
Titolo: Ms.
Nome: Regina
Cognome: García Beato
Email: send email
Telefono: +34 916249931

ES (GETAFE (MADRID)) coordinator 173˙370.60

Mappa

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 Word cloud

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resolution    aberrations    imaging    super    sheet    light    view    biological    microscopy   

 Obiettivo del progetto (Objective)

'Rapid high contrast imaging in combination with low light exposure makes light sheet microscopy particularly attractive for studying the three-dimensional development of biological specimens. Currently however, the highest resolution of light sheet microscopy can only be achieved with relatively transparent samples. To study more advanced stages of development, of particular interest in brain imaging, scattering and aberrations pose a significant obstacle to achieve super-resolution or even diffraction limited resolution. Adaptive optics can correct aberrations in situ, yet inhomogeneities in the sample can severely restrict the usable field-of-view. Here we propose the use of structured illumination with variable periodicity to reclaim the resolution for a wide field-of-view. This Marie Curie Fellowship will thus enable super-resolution light sheet imaging deep within turbid biological tissue.'

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