BIOSCENT

"BIOactive highly porous and injectable Scaffolds controlling stem cell recruitment, proliferation and differentiation and enabling angiogenesis for Cardiovascular ENgineered Tissues"

 Coordinatore UNIVERSITA DI PISA 

 Organization address address: Lungarno Pacinotti 43/44
city: PISA
postcode: 56126

contact info
Titolo: Dr.
Nome: Elisabetta
Cognome: Rosellini
Email: send email
Telefono: +39 050 511277
Fax: +39 050 511266

 Nazionalità Coordinatore Italy [IT]
 Sito del progetto http://inspiralia-delivery.eu/fp7bioscent_eu/
 Totale costo 8˙339˙349 €
 EC contributo 6˙305˙731 €
 Programma FP7-NMP
Specific Programme "Cooperation": Nanosciences, Nanotechnologies, Materials and new Production Technologies
 Code Call FP7-NMP-2007-LARGE-1
 Funding Scheme CP-IP
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-01-01   -   2013-12-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITA DI PISA

 Organization address address: Lungarno Pacinotti 43/44
city: PISA
postcode: 56126

contact info
Titolo: Dr.
Nome: Elisabetta
Cognome: Rosellini
Email: send email
Telefono: +39 050 511277
Fax: +39 050 511266

IT (PISA) coordinator 1˙157˙800.00
2    MEDIZINISCHE HOCHSCHULE HANNOVER

 Organization address address: Carl-Neuberg-Strasse 1
city: HANNOVER
postcode: 30625

contact info
Titolo: Prof.
Nome: Axel
Cognome: Haverich
Email: send email
Telefono: 495115000000
Fax: 495115000000

DE (HANNOVER) participant 772˙480.00
3    PERA INNOVATION LIMITED

 Organization address address: Innovation Park, Nottingham Road
city: MELTON MOWBRAY, LEICESTERSHIRE
postcode: LE13 OPB

contact info
Titolo: Mr.
Nome: Carlos
Cognome: Borlado
Email: send email
Telefono: +34 91 417 04 57
Fax: +34 91 556 34 15

UK (MELTON MOWBRAY, LEICESTERSHIRE) participant 752˙800.00
4    UNIVERSITA DEGLI STUDI DI PARMA

 Organization address address: VIA UNIVERSITA 12
city: PARMA
postcode: 43100

contact info
Titolo: Ms.
Nome: Nelida
Cognome: Ponticelli
Email: send email
Telefono: +39 0521 903272
Fax: +39 0521 903271

IT (PARMA) participant 555˙800.00
5    SORIN BIOMEDICA CARDIO S.R.L.

 Organization address address: VIA BENIGNO CRESPI 17
city: MILANO
postcode: 20159

contact info
Titolo: Ms.
Nome: Franca
Cognome: Tomeno
Email: send email
Telefono: +39 0161 487372
Fax: +39 0161 487853

IT (MILANO) participant 498˙600.00
6    THE UNIVERSITY OF MANCHESTER

 Organization address address: OXFORD ROAD
city: MANCHESTER
postcode: M13 9PL

contact info
Titolo: Ms.
Nome: Liz
Cognome: Fay
Email: send email
Telefono: +44 161 275 7114
Fax: +44 161 275 2445

UK (MANCHESTER) participant 392˙200.00
7    FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN NURNBERG

 Organization address address: SCHLOSSPLATZ 4
city: ERLANGEN
postcode: 91054

contact info
Titolo: Mr.
Nome: Ulrich
Cognome: Winderl
Email: send email
Telefono: -8533125
Fax: -8535321

DE (ERLANGEN) participant 386˙090.44
8    GmbH IBT - IMMUNOLOGICAL AND BIOCHEMICALTESTSYSTEMS GMBH*

 Organization address address: Aspenhaustrasse 25
city: Reutlingen
postcode: D-72770

contact info
Titolo: Ms.
Nome: Angelika
Cognome: Schützdeller
Email: send email
Telefono: 0049 (0)7121 514 634
Fax: 0049 (0)7121 514 635

DE (Reutlingen) participant 261˙600.00
9    TECNOLOGIAS AVANZADAS INSPIRALIA SL

 Organization address address: CALLE MIGUEL VILLANUEVA 2 6 PISO PUERTA 3
city: LOGRONO
postcode: 26001

contact info
Titolo: Mr.
Nome: Alfredo
Cognome: Sanchez
Email: send email
Telefono: 34914170457
Fax: +34 91 556 34 15

ES (LOGRONO) participant 251˙167.00
10    POLITECNICO DI TORINO

 Organization address address: Corso Duca degli Abruzzi 24
city: TORINO
postcode: 10129

contact info
Titolo: Dr.
Nome: Marica
Cognome: Pertile
Email: send email
Telefono: 390116000000
Fax: +39 011 5646999

IT (TORINO) participant 219˙930.00
11    KONINKLIJKE NEDERLANDSE AKADEMIE VAN WETENSCHAPPEN - KNAW

 Organization address address: KLOVENIERSBURGWAL 29 HET TRIPPENHUIS
city: AMSTERDAM
postcode: 1011 JV

contact info
Titolo: Mr.
Nome: Don
Cognome: Van Velzen
Email: send email
Telefono: +31 (0)302121800
Fax: +31 (0)302516464

NL (AMSTERDAM) participant 205˙680.00
12    Cambridge Research Biochemicals

 Organization address address: "Belasis Court, Belasis Hall Technology Park 10"
city: Billingham
postcode: TS23 4AZ

contact info
Titolo: Dr.
Nome: Emily
Cognome: Humphrys
Email: send email
Telefono: +44 (0) 1642 567 187
Fax: +44 (0) 1642 567 181

UK (Billingham) participant 196˙400.00
13    Chempilots a/s

 Organization address address: Rugmarken 24-26
city: FARUM
postcode: 3520

contact info
Titolo: Mr.
Nome: Elbek
Cognome: Christian
Email: send email
Telefono: 4544951661
Fax: +45 44 95 78 87

DK (FARUM) participant 179˙600.00
14    INSTITUTUL DE CHIMIE MACROMOLECULARA PETRU PONI

 Organization address address: Aleea Grigore Ghica Voda 41A
city: IASI
postcode: 700487

contact info
Titolo: Mr.
Nome: Constantin
Cognome: Ciobanu
Email: send email
Telefono: 400232000000
Fax: 400232000000

RO (IASI) participant 161˙200.00
15    USTAV EXPERIMENTALNI MEDICINY AKADEMIE VED CESKE REPUBLIKY VEREJNA VYZKUMNA INSTITUCE

 Organization address address: VIDENSKA 1083
city: PRAHA 4
postcode: 14220

contact info
Titolo: Prof.
Nome: Eva
Cognome: Sykova
Email: send email
Telefono: -41061812
Fax: -41062364

CZ (PRAHA 4) participant 159˙760.00
16    IMM RECHERCHE SAS

 Organization address address: BOULEVARD JOURDAN 42
city: PARIS
postcode: 75014

contact info
Titolo: Mr.
Nome: Luc
Cognome: Behr
Email: send email
Telefono: +33(0)156616822
Fax: +33(0)156616740

FR (PARIS) participant 152˙354.00
17    IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

 Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ

contact info
Titolo: Mr.
Nome: Shaun
Cognome: Power
Email: send email
Telefono: +44-0207 594 8773
Fax: +44-0207 594 8609

UK (LONDON) participant 2˙269.56
18    SORIN GROUP ITALIA SRL

 Organization address address: Via Benigno Crespi 17
city: Milano
postcode: 20159

contact info
Titolo: Ms.
Nome: Franca
Cognome: Tomeno
Email: send email
Telefono: +39 0161 487372
Fax: +39 0161 487853

IT (Milano) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

vitro    heart    cardiac    material    cells    innovative    scaffolds    implanted    differentiation    diseases    tissue    stem    tissues    population    world    cardiovascular    mortality    bioactive    engineering    repair    proliferation    guide   

 Obiettivo del progetto (Objective)

'Congenital and acquired diseases of the heart are the leading causes of morbidity and mortality in the world today; 7.2 million people die each year due to coronary heart disease, being the first cause of mortality in population above 60 years old, and the second cause after HIV in world wide young population. There is an urgent demand for new methods to repair and replace damaged cardiovascular tissues. One of the most promising ways to achieve this goal is the development of regenerative therapies aided with novel intelligent nanobiomaterials such as bioactive scaffolds. The overall objective of this project is the development of innovative bioactive polymeric scaffolds able to guide tissue formation from dissociated stem cells, for engineering autologous cardiovascular replacements, namely vascular tissues, heart valves and cardiac muscle. Two different strategies will be followed to approach creating new engineered tissue: 1.In vitro tissue engineering: according to the most frequent tissue engineering paradigm, cells will be seeded on a scaffold composed of synthetic polymer or natural material and the tissue will be matured in vitro in a bioreactor, in order to obtain a construct that can be implanted in the appropriate anatomic location as a prosthesis; 2.In vivo tissue engineering: unseeded scaffolds that attract endogenous cells and control cell proliferation and differentiation will be implanted to repopulate and remodel an altered cardiovascular tissue. The strong innovative content of the project is in the realisation of multifunctional scaffolds which can guide complex cellular processes such as adhesion, proliferation and differentiation, processes fundamental for tissue regeneration. It is therefore necessary to design integrated material scaffolds and culture environments, which can appropriately confer biochemical, morphological, electrical and mechanical stimuli to a developing tissue.'

Introduzione (Teaser)

Cardiovascular diseases such as myocardial infarction and stroke account for nearly half of the deaths in developed countries. A European consortium is proposing a new treatment for cardiac tissue repair through implantation of specialised scaffolds carrying stem cells.

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