ICEPURE

The impact of climatic and environmental factors on personal ultraviolet radiation exposure and human health

Coordinatore	KING'S COLLEGE LONDON    more  Organization address address: Strand city: LONDON postcode: WC2R 2LS contact info Titolo: Mr. Nome: Paul Cognome: Labbett Telefono: +44 20 78488184 Fax: 442078000000
Nazionalità Coordinatore	United Kingdom [UK]
Totale costo	4˙589˙794 €
EC contributo	3˙497˙616 €
Programma	FP7-ENVIRONMENT Specific Programme "Cooperation": Environment (including Climate Change)
Code Call	FP7-ENV-2008-1
Funding Scheme	CP-FP
Anno di inizio	2009
Periodo (anno-mese-giorno)	2009-02-01   -   2013-01-31

 Partecipanti

#	participant	country	role	EC contrib. [€]
1	KING'S COLLEGE LONDON  Organization address address: Strand city: LONDON postcode: WC2R 2LS contact info Titolo: Mr. Nome: Paul Cognome: Labbett Telefono: +44 20 78488184 Fax: 442078000000	UK (LONDON)	coordinator	665˙751.80
2	REGION HOVEDSTADEN  Organization address address: KONGENS VAENGE 2 city: HILLEROD postcode: 3400 contact info Titolo: Prof. Nome: Hans Christian Cognome: Wulf Telefono: -35313110 Fax: +45 35316010	DK (HILLEROD)	participant	1˙238˙484.00
3	FUNDACIO CENTRE DE RECERCA EN EPIDEMIOLOGIA AMBIENTAL - CREAL  Organization address address: Calle Doctor Aiguader 88 city: BARCELONA postcode: 8003 contact info Titolo: Ms. Nome: Gemma Cognome: Perello Telefono: +34 93 3160580 Fax: +34 93 3160575	ES (BARCELONA)	participant	335˙196.00
4	DANMARKS METEOROLOGISKE INSTITUT  Organization address address: Lyngbyvej 100 city: KOBENHAVN postcode: 2100 contact info Titolo: Mr. Nome: Erik Rex Cognome: Christensen Telefono: +453915 75 23 Fax: 4539157538	DK (KOBENHAVN)	participant	288˙845.00
5	UNIVERSYTET MEDYCZNY W LODZI.  Organization address address: Al. Kosciuszki, 4 city: LODZ postcode: 90419 contact info Titolo: Dr. Nome: Joanna Cognome: Narbutt Telefono: 48426867981 Fax: 48426884565	PL (LODZ)	participant	260˙740.00
6	VETERINAERMEDIZINISCHE UNIVERSITAET WIEN  Organization address address: Veterinaerplatz 1 city: VIENNA postcode: 1210 contact info Titolo: Dr. Nome: Sabine Cognome: Ecker Telefono: +43 1 250 77 1045 Fax: +43 1 250 77 1090	AT (VIENNA)	participant	240˙952.00
7	KAROLINSKA INSTITUTET  Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 contact info Titolo: Mr. Nome: Ingwar Cognome: Lennerfors Telefono: +468-608 92 23 Fax: +468-608 92 80	SE (STOCKHOLM)	participant	238˙950.00
8	HEALTH PROTECTION AGENCY HPA  Organization address address: Central Office - 7th Floor, Holborn Gate - High Holborn 330 city: LONDON postcode: WC1V 7PP contact info Titolo: Ms. Nome: Anne Cognome: Dempsey Telefono: +44 1235 824856 Fax: +44 1235 820580	UK (LONDON)	participant	228˙697.20

Mappa

 Word cloud

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 Obiettivo del progetto (Objective)

We will determine the adverse and beneficial health effects of personal UVR exposure and their relationships with climatic and environmental factors that modify the solar UVR spectrum. Date and time stamped personal electronic wristwatch dosimeters will be worn to measure individual UVR exposure over extended periods. Satellite and ground station data will be gathered to establish terrestrial UVR spectral irradiance, cloud, albedo, ozone and aerosol data, at the locations and times of exposure. These dosimeters will be used in field studies in working, water, beach and snow situations in four different countries, including studies with children. The personal dosimetric data combined with diary, ground station and satellite data will show the influence of behaviour, meteorological, environmental and cultural factors on individual UVR exposure doses. The interaction between the personal exposure parameters and the satellite and ground station data will enable the development of a humanized radiative transfer model to assess the future impact of climate change on UVR exposure. This is in contrast to previous models that assume exposure to a given fraction of ambient UVR. We will also determine the effect of UVR exposure on DNA damage and immunity in field conditions. Furthermore, the relationship between UVR exposure and vitamin D status will be determined, thus enabling a direct correlation between important risk and benefit biomarkers. We will also determine the spectral relationship between erythema, UVR-induced immunosuppression and vitamin D status. These studies will determine the value of erythema as a biological weighing function for UVR related health outcomes. Finally, we will perform a systematic review of a wide range of health outcomes from UVR exposure, and integrate our personal UVR exposure and modelling data into existing epidemiological data to estimate measurement error and any effects on current UVR dose response relationships and health outcome.

Introduzione (Teaser)

Skin cancer is a major health burden in Europe. The incidence of melanoma, the cause of most skin cancer deaths, has increased in recent decades.