CUSTOM

Drugs and Precursor Sensing by Complementing Low Cost Multiple Techniques

 Coordinatore SELEX ES SPA 

 Organization address address: VIA PIEMONTE 60
city: ROMA
postcode: 187

contact info
Titolo: Dr.
Nome: Annamaria
Cognome: Fiorello
Email: send email
Telefono: 390642000000

 Nazionalità Coordinatore Italy [IT]
 Totale costo 5˙295˙523 €
 EC contributo 3˙486˙406 €
 Programma FP7-SECURITY
Specific Programme "Cooperation": Security
 Code Call FP7-SEC-2009-1
 Funding Scheme CP
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-06-01   -   2013-11-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    SELEX ES SPA

 Organization address address: VIA PIEMONTE 60
city: ROMA
postcode: 187

contact info
Titolo: Dr.
Nome: Annamaria
Cognome: Fiorello
Email: send email
Telefono: 390642000000

IT (ROMA) coordinator 171˙648.00
2    GASERA OY

 Organization address address: TYKISTOKATU 4
city: TURKU
postcode: 20520

contact info
Titolo: Mr.
Nome: Juha-Pekka
Cognome: Kotro
Email: send email
Telefono: 358405000000
Fax: 35824690004

FI (TURKU) participant 600˙000.00
3    SELEX SISTEMI INTEGRATI SPA

 Organization address address: VIA TIBURTINA 1231
city: ROMA
postcode: 131

contact info
Titolo: Dr.
Nome: Anna Maria
Cognome: Fiorello
Email: send email
Telefono: +39 06 41503104
Fax: 390642000000

IT (ROMA) participant 563˙636.00
4    FUNDACION TECNALIA RESEARCH & INNOVATION

 Organization address address: PARQUE TECNOLOGICO DE MIRAMON PASEO MIKELETEGI 2
city: DONOSTIA-SAN SEBASTIAN
postcode: 20009

contact info
Titolo: Mr.
Nome: Francisco Jose
Cognome: Estensoro
Email: send email
Telefono: 34946430850
Fax: 34946460900

ES (DONOSTIA-SAN SEBASTIAN) participant 521˙600.00
5    AGENZIA NAZIONALE PER LE NUOVE TECNOLOGIE,L'ENERGIA E LO SVILUPPO ECONOMICO SOSTENIBILE

 Organization address address: Lungotevere Grande Ammiraglio Thaon di Revel 76
city: ROMA
postcode: 196

contact info
Titolo: Dr.
Nome: Antonio
Cognome: Palucci
Email: send email
Telefono: 390694000000
Fax: 390694000000

IT (ROMA) participant 373˙345.00
6    III V LAB GIE

 Organization address address: ROUTE DE NOZAY
city: MARCOUSSIS
postcode: 91460

contact info
Titolo: Dr.
Nome: Denis
Cognome: Mazerolle
Email: send email
Telefono: +33 01 30 77 68 93
Fax: +33 01 30 77 67 86

FR (MARCOUSSIS) participant 334˙222.00
7    CONSORZIO INTERUNIVERSITARIO NAZIONALE PER LA SCIENZA E TECNOLOGIA DEI MATERIALI

 Organization address address: Via Giusti 9
city: FIRENZE
postcode: 50121

contact info
Titolo: Prof.
Nome: Renato
Cognome: Seeber
Email: send email
Telefono: 390592000000
Fax: 39059373543

IT (FIRENZE) participant 280˙400.00
8    CONSIGLIO NAZIONALE DELLE RICERCHE

 Organization address address: Piazzale Aldo Moro 7
city: ROMA
postcode: 185

contact info
Titolo: Dr.
Nome: Sabato
Cognome: D'auria
Email: send email
Telefono: 390816000000
Fax: 390816000000

IT (ROMA) participant 275˙000.00
9    AALTO-KORKEAKOULUSAATIO

 Organization address address: OTAKAARI 1
city: ESPOO
postcode: 2150

contact info
Titolo: Prof.
Nome: Ilkka
Cognome: Tittonen
Email: send email
Telefono: +358 9 451 2287
Fax: +358 9 451 2222

FI (ESPOO) participant 176˙280.00
10    TURUN YLIOPISTO

 Organization address address: YLIOPISTONMAKI
city: TURUN YLIOPISTO
postcode: 20014

contact info
Titolo: Dr.
Nome: Tom
Cognome: Kuusela
Email: send email
Telefono: +358 2 333 6398
Fax: +358 2 333 5070

FI (TURUN YLIOPISTO) participant 150˙000.00
11    MINISTERE DU BUDGET DES COMPTES PUBLICS ET DE LA FONCTION PUBLIQUE ET DE LA REFORME DE L'ETAT

 Organization address city: PARIS
postcode: 75012

contact info
Titolo: Ms.
Nome: Jean-Claude
Cognome: Rigault
Email: send email
Telefono: +33 1 49 23 36 80
Fax: +33 1 49 23 36 80

FR (PARIS) participant 40˙275.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

technique    data    detection    molecules    screen    security    sensor    device    compounds    enhanced    custom    chemical    false    probability    alarm    classes    selectivity    detect    concentration    compact    lab    sensitive    portable    multiple    optical    monitoring    pod    analytes    array    organic    techniques    quality    sensitivity    precursors    sensing    drug    trade    fluorescence    spectroscopic    drugs    photoacoustic    ephedrine      

 Obiettivo del progetto (Objective)

'A large number of techniques have been developed in the latest decades, which are able to screen and identify specific molecules for drug precursors detection even at very low concentration in lab testing.Nevertheless the objective to build up a system which proves to be easy to use, compact, able to provide screening over a large number of compounds and discriminate them with low false alarm (FA) and high probability of detection (POD) is still an open issue.The project will focus on employing multiple techniques, integrating them in a complex system which employs them in a complimentary approach in order to identify an optimum trade-off between opposite requirements: compactness, simplicity, low cost vs. sensitivity low false alarm rate, selectivity. Known techniques, as fluorescence will be improved by mean of novel proteins, as antibodies to extend Probability of Detection (PoD). The techniques are: 1. A low cost, high data throughput sensing technique, based on UV-Vis-NIR fluorescence. Fluorescence will be enhanced by development of Organic macro-molecules sensitive to specific classes of compounds of interest (ephedrine, pseudoephedryne, P2P, …) in the domain of drug detection. The fluorescence analysis will be based on an ‘opto-chip’ which can incorporate an array of different properly engineered fluorescent chemical protein able to bind to the analytes with an ‘immuno-type’ reaction. An array of classes of compounds can be thus very fast discriminated by one-shot measurement. 2. A high sensitivity and selectivity, but compact and low weight, spectroscopic sensing technique in MIR–IR optical range, based on Laser PhotoAcoustic Sensor (LPAS). Detection of drug precursors based on spectroscopic techniques can guarantee a good selectivity, a low Probability of False Alarm and a suitable operation speed. The size of the photo-acoustic cell can be made as small as possible for a compact sensor and, depending on the performances, it can cost down to 1000€.'

Introduzione (Teaser)

Technological advances have increased the need for more cost-effective, portable, accurate and sensitive detection and identification of chemical substances. Potential applications range from warfare and border security to medicine manufacture, drug quality monitoring and illicit drug trade.

Descrizione progetto (Article)

While many methods can detect drug precursors at a very low concentration in a lab, a portable field system is yet to be developed. A recent project focused on creating such an affordable, sensitive and specific sensing system, which can screen over a large number of compounds.

The EU-funded project CUSTOM (Drugs and precursor sensing by complementing low cost multiple techniques) developed a portable optical sensing device for chemical compounds. The sensor can detect traces of drug precursors (ephedrine, safrole, acetic anhydride and benzyl methyl ketone) in air.

CUSTOM's sensor is modular, including a microfluidic circuit and a pre-concentrator unit to improve the sensitivity of detection. An incorporated microprocessor handles advanced data processing algorithms and a database. All sensor modules and a power supply are managed by a master control board. A touch screen display provides an easy-to-use machine/user interface.

The project's device uses two complementary sensing techniques. One is the rapid and highly sensitive spectroscopic technique based on photoacoustic transduction of infrared absorption. The second is a highly selective fluorescence method, enhanced by special organic macromolecules, binding the analytes through specific antibody-antigen interactions.

CUSTOM's developed sensor prototype was tested, with a reliability of detection of 98 % and limit of detection below the parts per million range. Successful commercialisation would significantly reduce trafficking of narcotics and counterfeit drugs across borders through detection capabilities in the micrograms per litre range. Law enforcement and customs officials would have a portable, user-friendly device for on-site inspection. Other areas of application include gas analysis, quality control, and safety and security monitoring systems.

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