PRIME-XS

Proteomics Research Infrastructure Maximising knowledge EXchange and access (XS)

 Coordinatore UNIVERSITEIT UTRECHT 

 Organization address address: Heidelberglaan 8
city: UTRECHT
postcode: 3584 CS

contact info
Titolo: Prof.
Nome: Albert
Cognome: Heck
Email: send email
Telefono: 31302536797
Fax: 31302518219

 Nazionalità Coordinatore Netherlands [NL]
 Totale costo 9˙898˙449 €
 EC contributo 7˙797˙040 €
 Programma FP7-INFRASTRUCTURES
Specific Programme "Capacities": Research infrastructures
 Code Call FP7-INFRASTRUCTURES-2010-1
 Funding Scheme CP-CSA-Infra
 Anno di inizio 2011
 Periodo (anno-mese-giorno) 2011-02-01   -   2015-01-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITEIT UTRECHT

 Organization address address: Heidelberglaan 8
city: UTRECHT
postcode: 3584 CS

contact info
Titolo: Prof.
Nome: Albert
Cognome: Heck
Email: send email
Telefono: 31302536797
Fax: 31302518219

NL (UTRECHT) coordinator 1˙920˙192.84
2    VIB

 Organization address address: Rijvisschestraat 120
city: ZWIJNAARDE - GENT
postcode: 9052

contact info
Titolo: Mr.
Nome: Rik
Cognome: Audenaert
Email: send email
Telefono: +32 9 244 66 11
Fax: +32 9 244 66 10

BE (ZWIJNAARDE - GENT) participant 1˙228˙935.99
3    EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZURICH

 Organization address address: Raemistrasse 101
city: ZUERICH
postcode: 8092

contact info
Titolo: Prof.
Nome: Ralph
Cognome: Schlapbach
Email: send email
Telefono: +41 44 635 39 20
Fax: +41 44 635 39 22

CH (ZUERICH) participant 1˙011˙713.11
4 KOBENHAVNS UNIVERSITET DK participant 676˙576.85
5    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE

 Organization address address: The Old Schools, Trinity Lane
city: CAMBRIDGE
postcode: CB2 1TN

contact info
Titolo: Mrs.
Nome: Renata
Cognome: Schaeffer
Email: send email
Telefono: +44 01223 764794
Fax: +44 01223 332988

UK (CAMBRIDGE) participant 657˙402.48
6    FUNDACIO CENTRE DE REGULACIO GENOMICA

 Organization address address: CARRER DOCTOR AIGUADER 88
city: BARCELONA
postcode: 8003

contact info
Titolo: Mr.
Nome: Stefan
Cognome: Ponisch
Email: send email
Telefono: +34 93 3160264
Fax: +34 93 3969983

ES (BARCELONA) participant 520˙534.19
7    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

 Organization address address: RUE LEBLANC 25
city: PARIS 15
postcode: 75015

contact info
Titolo: Dr.
Nome: Jérôme
Cognome: Garin
Email: send email
Telefono: +33 4 38 78 45 01
Fax: +33 4 38 78 51 55

FR (PARIS 15) participant 487˙120.10
8    EBERHARD KARLS UNIVERSITAET TUEBINGEN

 Organization address address: GESCHWISTER-SCHOLL-PLATZ
city: TUEBINGEN
postcode: 72074

contact info
Titolo: Prof.
Nome: Oliver
Cognome: Kohlbacher
Email: send email
Telefono: +49 7071 29 70457
Fax: +49 7071 29 5152

DE (TUEBINGEN) participant 388˙345.34
9    UNIVERSITAET ZUERICH

 Organization address address: Raemistrasse 71
city: ZURICH
postcode: 8006

contact info
Titolo: Dr.
Nome: Erich
Cognome: Brunner
Email: send email
Telefono: +4144635 3159
Fax: +4144635 6864

CH (ZURICH) participant 356˙395.67
10    FORSCHUNGSINSTITUT FUER MOLEKULARE PATHOLOGIE Ges.m.b.H

 Organization address address: Dr. Bohr-Gasse 7
city: VIENNA
postcode: 1030

contact info
Titolo: Ms.
Nome: Tanja
Cognome: Winkler
Email: send email
Telefono: +43 1 790 44 4410
Fax: +43 1 7987153

AT (VIENNA) participant 349˙045.31
11    EUROPEAN MOLECULAR BIOLOGY LABORATORY

 Organization address address: Meyerhofstrasse 1
city: HEIDELBERG
postcode: 69117

contact info
Titolo: Mr.
Nome: Henning
Cognome: Hermjakob
Email: send email
Telefono: +44 1223 494 671
Fax: +44 1223 494 468

DE (HEIDELBERG) participant 144˙839.23
12    MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

 Organization address address: Hofgartenstrasse 8
city: MUENCHEN
postcode: 80539

contact info
Nome: Ulrike
Cognome: Jendis
Email: send email
Telefono: +49 89 8578 3853
Fax: +49 89 8578 2235

DE (MUENCHEN) participant 55˙939.34

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

countries    proteomics    meetings    infrastructure    gene    latest    protein    expertise    prime    sequencing    training    distributed    publications    twelve    proteins    centres    translational    addition    facilities    facility    emphasis    expression    levels    aid    basis    scientific    xs    access    technologies    biological    courses    biomedical    tools    community    six    genome   

 Obiettivo del progetto (Objective)

'Genome sequencing initiated a new age in biology. Now, the emphasis is on the biological interpretation of the genome: zooming on the biological functioning of the gene-products, i.e. the proteins, emerging into a filed termed proteomics. Protein levels depend not only on mRNA levels, but also on translational controls & regulated degradation, making the measurement of expression at the protein level a prerequisite. The expression levels of all proteins, their modifications, localization and interactions, provide the most relevant single data set characterizing a biological system. The PRIME-XS consortium aims to provide state-of-the-art proteomics technologies to the European biological and biomedical research community. Its twelve partners, all leading in the field of proteomics, will provide access to their technology at six access facilities, distributed over Europe, will develop new technologies to better aid the research community in answering current day scientific questions, and will organize a wide range of meetings, courses and training events to disseminate their knowledge and expertise. Special emphasis will be placed on extending this knowledge to new member states of the European Union and other regions of Europe with less privileged availability of proteomics facilities. Access to the facilities will be advertised widely and will be open to all researchers in Europe, via an open, independently reviewed, online application system. Research proposals will be evaluated and, if selected, linked to an appropriate access facility. Many of the partners will be involved in research projects aiming at the development of new methods and tools to aid the access facilities and users. Results obtained will be communicated to both facility operators as well as user via publications, meetings and courses. Together with an industrial platform, users as well as other stakeholders, the consortium will also aim to provide the basis for a sustainable, Europe wide, proteomics community to maintain the high level of proteomics access and research, also beyond the duration of this project.'

Introduzione (Teaser)

The genome sequencing era is transitioning into proteomics, focusing on understanding of the biological functions of gene products, the proteins. A new proteomics research infrastructure grants access to state-of-the-art facilities, empowering proteomics research across Europe and strengthening scientific collaborations.

Descrizione progetto (Article)

Proteomics research requires substantial technology and expertise. Empowered by available sequenced genomes, the need for proteomics becomes more wide-spread, affecting key areas of biological and medical sciences. Many scientific studies can benefit from proteomics technologies applied to their field, and now such an opportunity has appeared.

The EU-funded project 'Proteomics research infrastructure maximising knowledge exchange and access (XS)' (http://www.primexs.eu/ (PRIME-XS)) is a trans-European consortium aiming to serve the entire European biomedical research community. Twelve leading centres in the field of proteomics from nine countries are developing the latest methods and tools to better aid the research community.

Access to advanced proteomics technologies is provided at six state-of-the art facilities, distributed across Europe and open to European researchers. Technologies offered by PRIME-XS include advanced peptide separation methods, latest-generation mass spectrometers and newly developed bioinformatics tools. In addition, training courses allow more researchers to take full advantage of proteomics technology.

Between 2011 and 2014, more than 100 proteomics research projects from 21 European countries were approved by external reviewers. Some of the projects are already completed, and others are currently being performed at consortium centres.

In addition, joint research activities in PRIME-XS are facilitating further advancement of proteomics, enabling technologies to progress to the critical next level. They streamline high-throughput proteomics information handling; study protein interaction networks and sub-cellular location; characterise protein post-translational modification; and search for novel disease biomarkers. Developed technologies are transferred to the access sites and made available to life science researchers in Europe. Many protocols developed in this ongoing project are also freely available on the PRIME-XS website.

Up to 2014, PRIME-XS enabled research that has already been reported in 80 scientific publications, with more under way. The PRIME-XS consortium is benefiting proteomics research and providing the basis for information access and sharing in the proteomics community beyond the duration of this project.

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