CDS-QUAMRI SIGNED
A Clinical Decision Support system based on Quantitative multimodal brain MRI for personalized treatment in neurological and psychiatric disorders
Total Cost €
0EC-Contrib. €
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0CDS-QUAMRI project word cloud
Explore the words cloud of the CDS-QUAMRI project. It provides you a very rough idea of what is the project "CDS-QUAMRI" about.
Project "CDS-QUAMRI" data sheet
The following table provides information about the project.
| Coordinator |
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Project website | http://cds-quamri.eu |
| Total cost | 3˙261˙125 € |
| EC max contribution | 2˙168˙125 € (66%) |
| Programme |
1. H2020-EU.3.1.6. (Health care provision and integrated care) |
| Code Call | H2020-PHC-2014-two-stage |
| Funding Scheme | RIA |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-09-01 to 2020-08-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV | DE (MUENCHEN) | coordinator | 636˙250.00 |
| 2 | UNIVERSITY COLLEGE LONDON | UK (LONDON) | participant | 566˙250.00 |
| 3 | EBERHARD KARLS UNIVERSITAET TUEBINGEN | DE (TUEBINGEN) | participant | 351˙250.00 |
| 4 | ACADEMISCH ZIEKENHUIS LEIDEN | NL (LEIDEN) | participant | 345˙000.00 |
| 5 | CHARITE - UNIVERSITAETSMEDIZIN BERLIN | DE (BERLIN) | participant | 269˙375.00 |
| 6 | EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH | CH (ZUERICH) | participant | 0.00 |
| 7 | GYROTOOLS GMBH | CH (WINTERTHUR) | participant | 0.00 |
Map
Project objective
A large number of neurological and psychiatric disorders lack objective criteria for primary diagnoses, early differential diagnosis with regard to subtypes in treatment response and disease progression or effective therapy monitoring resulting in a tremendous negative socio-economic impact. Scientific studies based on advanced MRI methods indicate that related patients show specific subtle changes in multiple MRI readouts that are only detectable by quantitative approaches. Existing tools for MRI data analysis are largely insufficient to maximise the use of advanced modality based, diverse and complex MRI data with deficiencies existing mainly in interoperability as well as data organisation, integration, analysis and exploitation in clinical decision making. Hence, the development of a clinical decision support system for neurological and psychiatric disorders is envisioned that is based on multimodal quantitative magnetic resonance imaging, advanced feature extraction and multi-parametric classification. To that the quantitative analysis of structural, functional and metabolic MRI data (11 modalities) shall be fully integrated into a single software framework for the first time; support of large data, interoperability and access for non-expert users shall be enabled and a machine learning based classification module shall be developed. The quantification and feature extraction algorithms for metabolic, perfusion, diffusion and functional imaging shall be enhanced to access the full information content of the data independent of vendor specific scan protocols as required for future use in diagnostics, stratification and monitoring of patients. The envisioned clinical decision support system shall be tested, optimized and demonstrated for major depression and multiple sclerosis, but can be extended to additional disorders by enabling large scale clinical trials and more widespread use in neuroscience as a basis for the future clinical decision making.
Deliverables
| Project Communication Initilization | Websites, patent fillings, videos etc. | 2020-04-01 17:21:11 |
Take a look to the deliverables list in detail: detailed list of CDS-QUAMRI deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2017 |
Yuriko Suzuki, Noriyuki Fujima, Tetsuo Ogino, James Alastair Meakin, Akira Suwa, Hiroyuki Sugimori, Marc Van Cauteren, Matthias J. P. van Osch Acceleration of ASL-based time-resolved MR angiography by acquisition of control and labeled images in the same shot (ACTRESS) published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.26667 |
Magnetic Resonance in Medicine | 2020-04-01 |
| 2017 |
Grussu Francesco, Battiston Marco, Prados Ferran, Schneider Torben, Kaden Enrico, Ourselin Sébastien, Samson Rebecca, Alexander Daniel, Gandini Wheeler-Kingshott Claudia A Unified Signal Readout for Reproducible Multimodal Characterisation of Brain Microstructure published pages: 3399, ISSN: , DOI: |
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). 2017 | 2020-04-01 |
| 2017 |
Suzuki, Y., van Osch, M. J.P. and Okell, TW. Improved Spatial encoding of vessel-selective pCASL: improving efficiency, minimising mislabelling, and shortening scan-time for artery specific MRA. published pages: 3617, ISSN: , DOI: |
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). 2017 | 2020-04-01 |
| 2017 |
Zhensen Chen, Xingxing Zhang, Chun Yuan, Xihai Zhao, Matthias J.P. van Osch Measuring the labeling efficiency of pseudocontinuous arterial spin labeling published pages: 1841-1852, ISSN: 0740-3194, DOI: 10.1002/mrm.26266 |
Magnetic Resonance in Medicine 77/5 | 2020-04-01 |
| 2016 |
Enrico Kaden, Frithjof Kruggel, Daniel C. Alexander Quantitative mapping of the per-axon diffusion coefficients in brain white matter published pages: 1752-1763, ISSN: 0740-3194, DOI: 10.1002/mrm.25734 |
Magnetic Resonance in Medicine 75/4 | 2020-04-01 |
| 2017 |
Venkateshwaran Murali Manohar Saipavitra, Giapitzakis Ioannis Angelos, Borbáth Tamás, Gärtner Matti, Henning Anke Qualitative Comparison between In Vivo J-Resolved Semi-LASER at 3 T and 9.4 T. published pages: 3015, ISSN: , DOI: |
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). 2017 | 2020-04-01 |
| 2017 |
Borbáth Tamás, Giapitzakis Ioannis Angelos, Venkateshwaran Murali Manohar Saipavitra, Henning Anke Fitting comparison for 9.4T 1D semi-LASER and 2D-J-resolved semi-LASER data. published pages: 2995, ISSN: , DOI: |
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). 2017 | 2020-04-01 |
| 2016 |
Gabriele Lohmann, Johannes Stelzer, Verena Zuber, Tilo Buschmann, Daniel Margulies, Andreas Bartels, Klaus Scheffler Task-Related Edge Density (TED)—A New Method for Revealing Dynamic Network Formation in fMRI Data of the Human Brain published pages: e0158185, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0158185 |
PLOS ONE 11/6 | 2020-04-01 |
| 2017 |
Suzuki, Y., Okell, TW., Teeuwisse, WM., Schmid, S., van der Plas, M., Chappell, MA., and van Osch, M. J.P. Silving the dark-side of multiband-ASL: A framework to correct for increased motion artefacts in MB-ASL due to sharp transitions in the level of background suppression. published pages: 3616, ISSN: , DOI: |
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). 2017 | 2020-04-01 |
| 2016 |
Francesco Grussu, Torben Schneider, Richard L. Yates, Hui Zhang, Claudia A.M. Gandini Wheeler-Kingshott, Gabriele C. DeLuca, Daniel C. Alexander A framework for optimal whole-sample histological quantification of neurite orientation dispersion in the human spinal cord published pages: 20-32, ISSN: 0165-0270, DOI: 10.1016/j.jneumeth.2016.08.002 |
Journal of Neuroscience Methods 273 | 2020-04-01 |
| 2017 |
Grussu Francesco, Ianus Andrada, Tur Carmen, Prados Ferran, Schneider Torben, Ourselin Sébastien, Drobnjak Ivana, Zhang Hui, Alexander Daniel, Gandini Wheeler-Kingshott Claudia Origin of the Time Dependence of the Diffusion-Weighted Signal in Spinal Cord White Matter. published pages: 843, ISSN: , DOI: |
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). 2017 | 2020-04-01 |
| 2016 |
Enrico Kaden, Nathaniel D. Kelm, Robert P. Carson, Mark D. Does, Daniel C. Alexander Multi-compartment microscopic diffusion imaging published pages: 346-359, ISSN: 1053-8119, DOI: 10.1016/j.neuroimage.2016.06.002 |
NeuroImage 139 | 2020-04-01 |
| 2017 |
Foley Cara, Kaden Enrico, Seunarine Kiran, Hall Matt, Carmichael David, Clayden Jonathan, Clark Chris Reproducibility of SMT-Based Microscopic Diffusion Anisotropy Imaging on a Clinical MRI System published pages: 3471, ISSN: , DOI: |
Proceedings of the International Society for Magnetic Resonance in Medicine (ISMRM). 2017 | 2020-04-01 |
| 2018 |
Matti Gärtner, M. Elisabetta Ghisu, Milan Scheidegger, Luisa Bönke, Yan Fan, Anna Stippl, Ana-Lucia Herrera-Melendez, Sophie Metz, Emilia Winnebeck, Maria Fissler, Anke Henning, Malek Bajbouj, Karsten Borgwardt, Thorsten Barnhofer, Simone Grimm Aberrant working memory processing in major depression: evidence from multivoxel pattern classification published pages: 1972-1979, ISSN: 0893-133X, DOI: 10.1038/s41386-018-0081-1 |
Neuropsychopharmacology 43/9 | 2020-04-01 |
| 2018 |
Yuriko Suzuki, Michael Helle, Peter Koken, Marc Van Cauteren, Matthias J. P. van Osch Simultaneous acquisition of perfusion image and dynamic MR angiography using time-encoded pseudo-continuous ASL published pages: 2676-2684, ISSN: 0740-3194, DOI: 10.1002/mrm.26926 |
Magnetic Resonance in Medicine 79/5 | 2020-04-01 |
| 2017 |
Matthias JP van Osch, Wouter M Teeuwisse, Zhensen Chen, Yuriko Suzuki, Michael Helle, Sophie Schmid Advances in arterial spin labelling MRI methods for measuring perfusion and collateral flow published pages: 1461-1480, ISSN: 0271-678X, DOI: 10.1177/0271678X17713434 |
Journal of Cerebral Blood Flow & Metabolism 38/9 | 2020-04-01 |
| 2018 |
Yuriko Suzuki, Thomas W. Okell, Michael A. Chappell, Matthias J.P. van Osch A framework for motion correction of background suppressed arterial spin labeling perfusion images acquired with simultaneous multi-slice EPI published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.27499 |
Magnetic Resonance in Medicine | 2020-04-01 |
| 2018 |
Gabriele Lohmann, Johannes Stelzer, Eric Lacosse, Vinod J. Kumar, Karsten Mueller, Esther Kuehn, Wolfgang Grodd, Klaus Scheffler LISA improves statistical analysis for fMRI published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-06304-z |
Nature Communications 9/1 | 2020-04-01 |
| 2018 |
Sahar Nassirpour, Paul Chang, Anke Henning MultiNet PyGRAPPA: Multiple neural networks for reconstructing variable density GRAPPA (a 1H FID MRSI study) published pages: 336-345, ISSN: 1053-8119, DOI: 10.1016/j.neuroimage.2018.08.032 |
NeuroImage 183 | 2020-04-01 |
| 2018 |
Sahar Nassirpour, Paul Chang, Nikolai Avdievitch, Anke Henning Compressed sensing for high-resolution nonlipid suppressed 1 H FID MRSI of the human brain at 9.4T published pages: 2311-2325, ISSN: 0740-3194, DOI: 10.1002/mrm.27225 |
Magnetic Resonance in Medicine 80/6 | 2020-04-01 |
| 2018 |
Ioannis-Angelos Giapitzakis, Tamas Borbath, Saipavitra Murali-Manohar, Nikolai Avdievich, Anke Henning Investigation of the influence of macromolecules and spline baseline in the fitting model of human brain spectra at 9.4T published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.27467 |
Magnetic Resonance in Medicine | 2020-04-01 |
| 2017 |
Gabriele Lohmann, Johannes Stelzer, Karsten Mueller, Eric Lacosse, Tilo Buschmann, Vinod J. Kumar, Wolfgang Grodd, Klaus Scheffler Inflated False Negative Rates Undermine Reproducibility In Task-Based fMRI published pages: , ISSN: 1097-0193, DOI: 10.1101/122788 |
bioRxiv | 2020-04-01 |
| 2017 |
Mahito Sugiyama, M Elisabetta Ghisu, Felipe Llinares-López, Karsten Borgwardt graphkernels: R and Python packages for graph comparison published pages: 530-532, ISSN: 1367-4803, DOI: 10.1093/bioinformatics/btx602 |
Bioinformatics 34/3 | 2020-04-01 |
| 2018 |
Arman Eshaghi, Ferran Prados, Wallace J. Brownlee, Daniel R. Altmann, Carmen Tur, M. Jorge Cardoso, Floriana De Angelis, Steven H. van de Pavert, Niamh Cawley, Nicola De Stefano, M. Laura Stromillo, Marco Battaglini, Serena Ruggieri, Claudio Gasperini, Massimo Filippi, Maria A. Rocca, Alex Rovira, Jaume Sastre-Garriga, Hugo Vrenken, Cyra E. Leurs, Joep Killestein, Lukas Pirpamer, Christian Enzinger, Sebastien Ourselin, Claudia A.M. Gandini Wheeler-Kingshott, Declan Chard, Alan J. Thompson, Daniel C. Alexander, Frederik Barkhof, Olga Ciccarelli Deep gray matter volume loss drives disability worsening in multiple sclerosis published pages: 210-222, ISSN: 0364-5134, DOI: 10.1002/ana.25145 |
Annals of Neurology 83/2 | 2020-04-01 |
| 2017 |
Francesco Grussu, Torben Schneider, Carmen Tur, Richard L. Yates, Mohamed Tachrount, Andrada IanuÅŸ, Marios C. Yiannakas, Jia Newcombe, Hui Zhang, Daniel C. Alexander, Gabriele C. DeLuca, Claudia A. M. Gandini Wheeler-Kingshott Neurite dispersion: a new marker of multiple sclerosis spinal cord pathology? published pages: 663-679, ISSN: 2328-9503, DOI: 10.1002/acn3.445 |
Annals of Clinical and Translational Neurology 4/9 | 2020-04-01 |
| 2018 |
Yuriko Suzuki, Matthias J. P. van Osch, Noriyuki Fujima, Thomas W. Okell Optimization of the spatial modulation function of vessel-encoded pseudo-continuous arterial spin labeling and its application to dynamic angiography published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.27418 |
Magnetic Resonance in Medicine | 2020-04-01 |
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