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Lensless SIGNED

High-resolution microscopy without lenses: a new generation of imaging technology

Total Cost €


EC-Contrib. €






 Lensless project word cloud

Explore the words cloud of the Lensless project. It provides you a very rough idea of what is the project "Lensless" about.

metrology    et    ray    objects    surprisingly    wavelengths    coordinated    sharp    conventional    extend    diagnostics    profiling    alternative    framework    source    shown    dependent    050618    expertise    laser    microscopy    components    provides    al    care    powerful    feasible    starting    minimally    fundamental    shorter    point    patent    wafers    robustness    generation    endoscopic    contrast    detecting    euv    wavelength    advantages    size    excellent    nl2013    world    image    sensor    actual    soft    simplicity    transmission    forge    light    pct    retrieved    fibers    propagation    surface    elegant    numerical    parallel    realization    cultures    reconstructed    ultra    differences    medical    alike    cell    retrieval    smartphone    prospects    reflection    tool    invasive    resolution    precision    me    optical    imaging    works    industrial    amplitude    science    lensless    countries    wave    witte    object    microscopes    lithographic    lenses   

Project "Lensless" data sheet

The following table provides information about the project.


Organization address
address: DE BOELELAAN 1105
postcode: 1081 HV

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Project website
 Total cost 1˙500˙000 €
 EC max contribution 1˙500˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2014-STG
 Funding Scheme ERC-STG
 Starting year 2015
 Duration (year-month-day) from 2015-05-01   to  2020-04-30


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VU NL (AMSTERDAM) coordinator 1˙500˙000.00


 Project objective

Lensless imaging is an elegant approach to microscopy, in which a sharp image of an object is retrieved by numerical means rather than by actual optical components such as lenses. Such an approach allows high-resolution imaging using only a light source and an image sensor. Multi-wavelength phase retrieval (Witte et al., patent application PCT/NL2013/050618) provides a general framework for lensless imaging, which allows the development of surprisingly simple yet high-resolution imaging devices. By detecting wavelength-dependent differences in wave propagation, I have recently shown that amplitude and phase of an object field can be reconstructed with high contrast and resolution. This approach works for complex objects in both reflection and transmission. As such, lensless microscopes have advantages in size, cost, robustness and simplicity, and provide a powerful alternative to conventional imaging systems in many applications. My aim with this proposal is to advance this new technology towards high-impact applications, and to forge a coordinated research program on lensless imaging technology and its applications. I will develop lensless microscopes to image many cell cultures in parallel, as well as smartphone-based lensless microscopes for low-cost point-of-care diagnostics in third-world countries. Lensless microscopy through optical fibers will be implemented as a novel tool for minimally invasive endoscopic imaging. Since the technology does not require precision optical components, I will be able to extend it to shorter wavelengths. Applications in EUV metrology and soft-X-ray imaging become feasible, such as ultra-high-resolution surface profiling of lithographic wafers. This program provides exciting new prospects for fundamental science, industrial metrology and medical diagnostics alike. My expertise in lensless imaging and laser development provide me with an excellent starting point for the realization of such a new generation of imaging technology.


year authors and title journal last update
List of publications.
2018 G. S. M. Jansen, A. de Beurs, X. Liu, K. S. E. Eikema, S. Witte
Diffractive shear interferometry for extreme ultraviolet high-resolution lensless imaging
published pages: 12479, ISSN: 1094-4087, DOI: 10.1364/OE.26.012479
Optics Express 26/10 2019-12-16
2019 G. S. M. Jansen, X. Liu, K. S. E. Eikema, S. Witte
Broadband extreme ultraviolet dispersion measurements using a high-harmonic source
published pages: 3625, ISSN: 0146-9592, DOI: 10.1364/ol.44.003625
Optics Letters 44/15 2019-12-16
2018 S. Edward, A. Antoncecchi, H. Zhang, H. Sielcken, S. Witte, P. C. M. Planken
Detection of periodic structures through opaque metal layers by optical measurements of ultrafast electron dynamics
published pages: 23380, ISSN: 1094-4087, DOI: 10.1364/oe.26.023380
Optics Express 26/18 2019-12-16
2018 Dirk E. Boonzajer Flaes, Stefan Witte
Interference probe ptychography for computational amplitude and phase microscopy
published pages: 31372, ISSN: 1094-4087, DOI: 10.1364/oe.26.031372
Optics Express 26/24 2019-12-16
2019 Mengqi Du, Kjeld S. E. Eikema, Stefan Witte
Computational-imaging-based optical coherence tomography in time- and frequency-domain
published pages: 3141, ISSN: 2578-7519, DOI: 10.1364/osac.2.003141
OSA Continuum 2/11 2019-12-16
2018 L. Freisem, G. S. M. Jansen, D. Rudolf, K. S. E. Eikema, S. Witte
Spectrally resolved single-shot wavefront sensing of broadband high-harmonic sources
published pages: 6860, ISSN: 1094-4087, DOI: 10.1364/OE.26.006860
Optics Express 26/6 2019-12-16
2016 G. S. M. Jansen, D. Rudolf, L. Freisem, K. S. E. Eikema, S. Witte
Spatially resolved Fourier transform spectroscopy in the extreme ultraviolet
published pages: 1122, ISSN: 2334-2536, DOI: 10.1364/OPTICA.3.001122
Optica 3/10 2019-06-05
2017 M. J. Deuzeman, A. S. Stodolna, E. E. B. Leerssen, A. Antoncecchi, N. Spook, T. Kleijntjens, J. Versluis, S. Witte, K. S. E. Eikema, W. Ubachs, R. Hoekstra, O. O. Versolato
Ion distribution and ablation depth measurements of a fs-ps laser-irradiated solid tin target
published pages: 103301, ISSN: 0021-8979, DOI: 10.1063/1.4977854
Journal of Applied Physics 121/10 2019-06-05

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