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MEDILIGHT

Miniaturized smart system for light stimulation and monitoring of wound healing

Total Cost €

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EC-Contrib. €

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Partnership

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 MEDILIGHT project word cloud

Explore the words cloud of the MEDILIGHT project. It provides you a very rough idea of what is the project "MEDILIGHT" about.

battery    device    multiple    care    sensors    interconnection    professionals    module    algorithms    spatial    electrical    optimized    surface    data    dressing    controller    heterogeneous    edge    layers    monitoring    temperature    waveguides    oxygen    analog    optical    coupling    wound    feedback    transmission    healing    combining    photodiode    structures    vitro    loops    exposure    acquisition    status    pcb    billion    red    interconnected    annually    keratinocytes    blue    integration    hygiene    waveguide    disposable    620    burden    vivo    predominantly    containing    parts    consist    resolution    embedding    plug    patients    soft    wounds    antibacterial    programs    proven    health    visible    approximately    mechanically    fibroblasts    technologies    fabrication    deeper    750nm    history    induces    stretchable    animal    temporal    monitor    blood    spectrum    backed    smart    compliant    light    450    million    medical    chronic    therapy    electronics    comfort    monitored    rechargeable    professional    respective    leds    skin    self    schemes    electronic    explored    495nm    therapeutic   

Project "MEDILIGHT" data sheet

The following table provides information about the project.

Coordinator
TECHNISCHE UNIVERSITAT BERLIN 

Organization address
address: STRASSE DES 17 JUNI 135
city: BERLIN
postcode: 10623
website: www.tu-berlin.de

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website http://www.medilight-project.eu
 Total cost 2˙988˙034 €
 EC max contribution 2˙475˙310 € (83%)
 Programme 1. H2020-EU.2.1.1.1. (A new generation of components and systems: Engineering of advanced embedded and energy and resource efficient components and systems)
 Code Call H2020-ICT-2014-1
 Funding Scheme RIA
 Starting year 2015
 Duration (year-month-day) from 2015-02-01   to  2018-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    TECHNISCHE UNIVERSITAT BERLIN DE (BERLIN) coordinator 587˙500.00
2    URGO RECHERCHE INNOVATION ET DEVELOPPEMENT FR (CHENOVE) participant 504˙308.00
3    MICROSEMI SEMICONDUCTOR LIMITED UK (GWENT) participant 410˙000.00
4    RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG DE (HEIDELBERG) participant 401˙218.00
5    SIGNALGENERIX LIMITED CY (LIMASSOL) participant 324˙375.00
6    AMIRES SRO CZ (PRAHA 6) participant 151˙750.00
7    LABORATOIRES URGO FR (Chenove) participant 96˙159.00
8    CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT CH (NEUCHATEL) participant 0.00

Map

 Project objective

Chronic wounds represent a significant burden to patients, health care professionals, and health care systems, affecting over 40 million patients and creating costs of approximately 40 billion € annually. Goal of the project is the fabrication of a medical device for professional wound care. The device will use recently proven therapeutic effects of visible light to enhance the self-healing process and monitor the status and history of the wound during therapy. Light exposure in the red part of the spectrum (620-750nm) induces growth of keratinocytes and fibroblasts in deeper layers of the skin. The blue part of the spectrum (450–495nm) is known to have antibacterial effects predominantly at the surface layers of the skin. In order to be compliant with hygiene requirements the system will consist of two parts: 1. a disposable wound dressing with embedded optical waveguides and integrated sensors for the delivery of light and monitoring (temperature and blood oxygen) of the wound. 2. a soft and compliant electronic module for multiple use containing LEDs, a photodiode, a controller, analog data acquisition, a rechargeable battery, and a data transmission unit. Both parts of the device will be interconnected by a mechanically robust plug, enabling a low loss coupling of light into the waveguide structures and electrical interconnection to the sensors. The status of the wound will be monitored with temporal and low level spatial resolution. The electronic module will be optimized for functionality and user comfort, combining leading edge heterogeneous integration technologies (PCB embedding) and stretchable electronics approaches. The detailed effects of light-exposure schemes will be explored and backed by in-vitro and in-vivo animal studies. Results will be used to develop smart algorithms and implement it into respective programs and feedback loops of the device.

 Deliverables

List of deliverables.
Webpage of the project Websites, patent fillings, videos etc. 2019-02-26 10:34:26
Development of the preliminary exploitation, dissemination and Communication strategy and the project brochure Documents, reports 2019-02-26 10:34:26

Take a look to the deliverables list in detail:  detailed list of MEDILIGHT deliverables.

 Publications

year authors and title journal last update
List of publications.
2015 Kuch, N.
Optimization of Keratinocyte-Fibroblast Co-Cultures
published pages: , ISSN: , DOI:
2019-05-30
2015 Klapczynski, A.
Effects of blue light irradiation on human dermal fibroblasts
published pages: , ISSN: , DOI:
2019-05-30
2017 Enzlein, T.
Influence of light on adipose derived stem cells
published pages: , ISSN: , DOI:
2019-05-30
2016 Anja Becker, Anna Klapczynski, Natalia Kuch, Fabiola Arpino, Katja Simon-Keller, Carolina De La Torre, Carsten Sticht, Frank A. van Abeelen, Gerrit Oversluizen, Norbert Gretz
Gene expression profiling reveals aryl hydrocarbon receptor as a possible target for photobiomodulation when using blue light
published pages: 33847, ISSN: 2045-2322, DOI: 10.1038/srep33847
Scientific Reports 6 2019-05-30
2016 Kuch, N.
Co-cultures of Fibroblasts and Keratinocytes under the influence of blue light
published pages: , ISSN: , DOI:
2019-05-30
2015 Distler, E.
Influence of blue LED irradiation on human melanoma cells
published pages: , ISSN: , DOI:
2019-05-30
2017 Schreiner, S.
Influence of Red Light Irradiation on Melanoma Cells
published pages: , ISSN: , DOI:
2019-05-30
2017 Becker, A.
Influence of photobiomodulation with blue light on the metabolism, proliferation and gene expression of human keratinocytes
published pages: , ISSN: , DOI:
2019-05-30
2018 Hüllen, A.
Influence of Blue Light Irradiation on Bacteria using Escherichia coli as a model organism
published pages: , ISSN: , DOI:
2019-05-30
2017 Schreiner, S.
Effects of Blue Light Irradiation on Human Melanoma Cells
published pages: , ISSN: , DOI:
2019-05-30
2018 Arif ul Maula Khan, Angelo Torelli, Ivo Wolf, Norbert Gretz
AutoCellSeg: robust automatic colony forming unit (CFU)/cell analysis using adaptive image segmentation and easy-to-use post-editing techniques
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-24916-9
Scientific Reports 8/1 2019-05-30

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The information about "MEDILIGHT" are provided by the European Opendata Portal: CORDIS opendata.

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