MEDILIGHT
Miniaturized smart system for light stimulation and monitoring of wound healing
Total Cost €
0EC-Contrib. €
0Partnership
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0MEDILIGHT project word cloud
Explore the words cloud of the MEDILIGHT project. It provides you a very rough idea of what is the project "MEDILIGHT" about.
Project "MEDILIGHT" data sheet
The following table provides information about the project.
| Coordinator |
TECHNISCHE UNIVERSITAT BERLIN
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Project website | http://www.medilight-project.eu |
| Total cost | 2˙988˙034 € |
| EC max contribution | 2˙475˙310 € (83%) |
| Programme |
1. H2020-EU.2.1.1.1. (A new generation of components and systems: Engineering of advanced embedded and energy and resource efficient components and systems) |
| Code Call | H2020-ICT-2014-1 |
| Funding Scheme | RIA |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-02-01 to 2018-07-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | TECHNISCHE UNIVERSITAT BERLIN | DE (BERLIN) | coordinator | 587˙500.00 |
| 2 | URGO RECHERCHE INNOVATION ET DEVELOPPEMENT | FR (CHENOVE) | participant | 504˙308.00 |
| 3 | MICROSEMI SEMICONDUCTOR LIMITED | UK (GWENT) | participant | 410˙000.00 |
| 4 | RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG | DE (HEIDELBERG) | participant | 401˙218.00 |
| 5 | SIGNALGENERIX LIMITED | CY (LIMASSOL) | participant | 324˙375.00 |
| 6 | AMIRES SRO | CZ (PRAHA 6) | participant | 151˙750.00 |
| 7 | LABORATOIRES URGO | FR (Chenove) | participant | 96˙159.00 |
| 8 | CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT | CH (NEUCHATEL) | participant | 0.00 |
Map
Project objective
Chronic wounds represent a significant burden to patients, health care professionals, and health care systems, affecting over 40 million patients and creating costs of approximately 40 billion € annually. Goal of the project is the fabrication of a medical device for professional wound care. The device will use recently proven therapeutic effects of visible light to enhance the self-healing process and monitor the status and history of the wound during therapy. Light exposure in the red part of the spectrum (620-750nm) induces growth of keratinocytes and fibroblasts in deeper layers of the skin. The blue part of the spectrum (450–495nm) is known to have antibacterial effects predominantly at the surface layers of the skin. In order to be compliant with hygiene requirements the system will consist of two parts: 1. a disposable wound dressing with embedded optical waveguides and integrated sensors for the delivery of light and monitoring (temperature and blood oxygen) of the wound. 2. a soft and compliant electronic module for multiple use containing LEDs, a photodiode, a controller, analog data acquisition, a rechargeable battery, and a data transmission unit. Both parts of the device will be interconnected by a mechanically robust plug, enabling a low loss coupling of light into the waveguide structures and electrical interconnection to the sensors. The status of the wound will be monitored with temporal and low level spatial resolution. The electronic module will be optimized for functionality and user comfort, combining leading edge heterogeneous integration technologies (PCB embedding) and stretchable electronics approaches. The detailed effects of light-exposure schemes will be explored and backed by in-vitro and in-vivo animal studies. Results will be used to develop smart algorithms and implement it into respective programs and feedback loops of the device.
Deliverables
| Webpage of the project | Websites, patent fillings, videos etc. | 2019-02-26 10:34:26 |
| Development of the preliminary exploitation, dissemination and Communication strategy and the project brochure | Documents, reports | 2019-02-26 10:34:26 |
Take a look to the deliverables list in detail: detailed list of MEDILIGHT deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2015 |
Kuch, N. Optimization of Keratinocyte-Fibroblast Co-Cultures published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2015 |
Klapczynski, A. Effects of blue light irradiation on human dermal fibroblasts published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2017 |
Enzlein, T. Influence of light on adipose derived stem cells published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2016 |
Anja Becker, Anna Klapczynski, Natalia Kuch, Fabiola Arpino, Katja Simon-Keller, Carolina De La Torre, Carsten Sticht, Frank A. van Abeelen, Gerrit Oversluizen, Norbert Gretz Gene expression profiling reveals aryl hydrocarbon receptor as a possible target for photobiomodulation when using blue light published pages: 33847, ISSN: 2045-2322, DOI: 10.1038/srep33847 |
Scientific Reports 6 | 2019-05-30 |
| 2016 |
Kuch, N. Co-cultures of Fibroblasts and Keratinocytes under the influence of blue light published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2015 |
Distler, E. Influence of blue LED irradiation on human melanoma cells published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2017 |
Schreiner, S. Influence of Red Light Irradiation on Melanoma Cells published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2017 |
Becker, A. Influence of photobiomodulation with blue light on the metabolism, proliferation and gene expression of human keratinocytes published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2018 |
Hüllen, A. Influence of Blue Light Irradiation on Bacteria using Escherichia coli as a model organism published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2017 |
Schreiner, S. Effects of Blue Light Irradiation on Human Melanoma Cells published pages: , ISSN: , DOI: |
2019-05-30 | |
| 2018 |
Arif ul Maula Khan, Angelo Torelli, Ivo Wolf, Norbert Gretz AutoCellSeg: robust automatic colony forming unit (CFU)/cell analysis using adaptive image segmentation and easy-to-use post-editing techniques published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-24916-9 |
Scientific Reports 8/1 | 2019-05-30 |
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The information about "MEDILIGHT" are provided by the European Opendata Portal: CORDIS opendata.