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OMA SIGNED

Optimization of Medical Accelerators

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EC-Contrib. €

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Project "OMA" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF LIVERPOOL 

Organization address
address: BROWNLOW HILL 765 FOUNDATION BUILDING
city: LIVERPOOL
postcode: L69 7ZX
website: www.liverpool.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://www.oma-project.eu
 Total cost 3˙871˙703 €
 EC max contribution 3˙871˙703 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2015
 Funding Scheme MSCA-ITN-ETN
 Starting year 2016
 Duration (year-month-day) from 2016-02-01   to  2020-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) coordinator 273˙287.00
2    FONDAZIONE CENTRO NAZIONALE DI ADROTERAPIA ONCOLOGICA IT (PAVIA PV) participant 516˙122.00
3    THE UNIVERSITY OF MANCHESTER UK (MANCHESTER) participant 273˙287.00
4    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 273˙287.00
5    EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH CH (GENEVA 23) participant 265˙226.00
6    PAUL SCHERRER INSTITUT CH (VILLIGEN PSI) participant 265˙226.00
7    EBG (Entwicklungs- und Betriebsgesellschaft) MedAustron GmbH AT (Wiener Neustadt) participant 255˙934.00
8    AMSTERDAM SCIENTIFIC INSTRUMENTS BV NL (AMSTERDAM) participant 255˙374.00
9    ION BEAM APPLICATIONS SA BE (OTTIGNIES LOUVAIN LA NEUVE) participant 250˙560.00
10    GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG GMBH DE (DARMSTADT) participant 249˙216.00
11    LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN DE (MUENCHEN) participant 249˙216.00
12    VIALUX MESSTECHNIK + BILDVERARBEITUNG GMBH DE (CHEMNITZ) participant 249˙216.00
13    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) participant 247˙872.00
14    UNIVERSIDAD DE SEVILLA ES (SEVILLA) participant 247˙872.00
15    Clatterbridge Cancer Centre UK (Birkenhead) partner 0.00
16    COSYLAB LABORATORIJ ZA KONTROLNE SISTEME DD SI (LJUBLJANA) partner 0.00
17    Fistral Training and Consultancy Ltd. UK (Glasgow) partner 0.00
18    Holdsworth Associates UK (Cambridge) partner 0.00
19    INVENTYA LTD UK (WARRINGTON) partner 0.00
20    ISTITUTO NAZIONALE DI FISICA NUCLEARE IT (FRASCATI) partner 0.00
21    SCIENCE AND TECHNOLOGY FACILITIES COUNCIL UK (SWINDON) partner 0.00
22    The Christie UK (Manchester) partner 0.00
23    UK Intellectual Property Office UK (Newport) partner 0.00
24    UNIVERSITY OF LANCASTER UK (LANCASTER) partner 0.00

Map

 Project objective

Cancer is a major social problem, and it is the main cause of death between the ages 45-65 years. In the treatment of cancer, radio therapy (RT) plays an essential role. RT with hadrons (protons and light ions), due to their unique physical and radiobiological properties, offers several advantages over photons for specific cancer types. In particular, they penetrate the patient with minimal diffusion, they deposit maximum energy at the end of their range, and they can be shaped as narrow focused and scanned pencil beams of variable penetration depth. Although significant progress has been made in the use of particle beams for cancer treatment, an extensive research and development program is still needed to maximize the healthcare benefits from these therapies. The Optimization of Medical Accelerators (OMA) is the aim of the here-proposed European Training Network, in line with the requirements of the EC’s Medical Exposure Directive. OMA joins universities, research centers and clinical facilities with industry partners to address the challenges in treatment facility design and optimization, numerical simulations for the development of advanced treatment schemes, and in beam imaging and treatment monitoring. The proposed R&D program ranges from life sciences (oncology, cell and micro biology and medical imaging.), physics and accelerator sciences, mathematics and IT, to engineering. It is hence ideally suited for an innovative training of early stage researchers. By closely linking all above research areas, OMA will provide an interdisciplinary education to its Fellows. This will equip them with solid knowledge also in research areas adjacent to their core research field, as well as with business competences and hence give them a perfect basis for a career in research.

 Deliverables

List of deliverables.
PC readout software Documents, reports 2019-07-09 19:33:25
Results from MC studies into detector performance with LMU and CERN Documents, reports 2019-07-09 19:33:24
Benefit analysis Documents, reports 2019-07-09 19:33:24
First software version ready for tests Demonstrators, pilots, prototypes 2019-07-09 19:33:25
First integrated model for treatment planning and imaging Documents, reports 2019-07-09 19:33:24
Project brochure Websites, patent fillings, videos etc. 2019-07-09 19:33:24
Project leaflet Websites, patent fillings, videos etc. 2019-07-09 19:33:24
OMA web site Websites, patent fillings, videos etc. 2019-07-09 19:33:24
Modifications to CTF3 and tests at CERN Demonstrators, pilots, prototypes 2019-07-09 19:33:24
Prototype design Demonstrators, pilots, prototypes 2019-07-09 19:33:25

Take a look to the deliverables list in detail:  detailed list of OMA deliverables.

 Publications

year authors and title journal last update
List of publications.
2019 E. Oponowicz, H. Owen
Superconducting Dipole Design for a Proton Computed Tomography Gantry
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2019-thpmp054
Proceedings IPAC\'19, 10th International Particle Accelerator Conference, Melbourne, Australia 2019-12-16
2019 J. S.L. Yap, N. J. S. Bal, A. Kacperek, J. Resta-Lopez, C.P. Welsch et al.
Beam Characterisation Using MEDIPIX3 and EBT3 Film at the Clatterbridge Proton Therapy Beamline
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2019-thpmp033
Proceedings IPAC\'19, 10th International Particle Accelerator Conference, Melbourne, Australia 2019-12-16
2018 R. Schnuerer, J S.L. Yap, H. Zhang, G.J. Haefeli, O. Girard and C.P. Welsch
Implementation of a non-invasive online beam monitor at a 60 MeV proton therapy beamline
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2018-mopml024
Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada 2019-12-16
2019 Laurent Kelleter, Benjamin Zhen-Hong Tham, Ruben Saakyan, Jennifer Griffiths, Richard Amos, Simon Jolly, Adam Gibson
Technical Note: Simulation of dose buildup in proton pencil beams
published pages: 3734-3738, ISSN: 0094-2405, DOI: 10.1002/mp.13660
Medical Physics 46/8 2019-12-16
2019 T. Boon-Keng, Y. Xie, F. O’Grady, A. Lalonde, J. Petzoldt, J. Smeets, G. Janssens
OC-0187 Comparison of proton range predictions between Single- and Dual-Energy CT using prompt gamma imaging
published pages: S95-S96, ISSN: 0167-8140, DOI: 10.1016/s0167-8140(19)30607-3
Radiotherapy and Oncology 133 2019-12-16
2018 S. Srinivasan, P. A. Duperrex
Reentrant cavity resonator for low intensities proton beam measurements
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2018-wepal069
Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada 2019-12-16
2019 C. Khamfongkhruea, G. Janssens, J. Petzoldt, J. Smeets, G. Pausch, C. Richter
OC-0566 Range verification in proton therapy: Can prompt-gamma imaging identify the source of deviation?
published pages: S296-S297, ISSN: 0167-8140, DOI: 10.1016/s0167-8140(19)30986-7
Radiotherapy and Oncology 133 2019-12-16
2017 F. Hueso-Gonzalez, G. Pausch, J. Petzoldt, K. E. Romer, W. Enghardt
Prompt Gamma Rays Detected With a BGO Block Compton Camera Reveal Range Deviations of Therapeutic Proton Beams
published pages: 76-86, ISSN: 2469-7311, DOI: 10.1109/tns.2016.2622162
IEEE Transactions on Radiation and Plasma Medical Sciences 1/1 2019-12-16
2018 A. Vnuchenko, A. Latina, C. Bruni, M. El Khaldi, A. Faus Golfe, P. Lepercq, C. Vallerand
Start-to-End Beam Dynamic Simulations for PRAE
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2018-mopml044
Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada 2019-12-16
2017 A. Vnuchenko, N. Catalan Lasheras, G. Mcmonagle, I. Syratchev, W. Wuensch, A. Faus Golfe, T. Argyropoulos, C. Blanch, D. Esperante, J. Giner
Design and Construction of a High-Gradient RF Lab at IFIC-Valencia
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2017-thpik081
Proceedings IPAC’17, 8th International Particle Accelerator Conference, Copenhagen, Denmark 2019-12-16
2018 A. Vnuchenko, S. Benedetti, C. Blanch Gutiérrez, N. Catalán Lasheras, D. Esperante Pereira, A. Faus-Golfe, A. Grudiev, B. Koubek, T. Lucas, G. McMonagle, I. Syratchev, B. J. Woolley, W. Wuensch
High Gradient Performance of an S-Band Backward Traveling Wave Accelerating Structure for Medical Hadron Therapy Accelerators
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2018-mopml043
Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada 2019-12-16
2018 D. Esperante, C. Blanch, M. Boronat, J. Fuster, D. Gonzalez Iglesias, A. Vnuchenko, B. Gimeno, N. Catalan Lasheras, G. Mcmonagle, I. Syratchev, W. Wuensch, B. Woolley, A. Faus Golfe
Construction and commissioning of the S-Band high gradient RF laboratory at IFIC
published pages: 82024, ISSN: 1742-6588, DOI: 10.1088/1742-6596/1067/8/082024
Journal of Physics: Conference Series 1067 2019-12-16
2018 S. Toscano, K. Souris, E. Sterpin, G. Janssens, J. Petzoldt, F. Vander Stappen, J. Smeets, X. Geets, K. Teo
OC-0081: From range measurements to dose: in-vivo dosimetry using the prompt gamma camera
published pages: S40, ISSN: 0167-8140, DOI: 10.1016/s0167-8140(18)30391-8
Radiotherapy and Oncology 127 2019-12-16
2019 S. Srinivasan, P. A. Duperrex, J. M. Schippers
Quadrated dielectric-filled reentrant cavity resonator as a proton beam position diagnostic
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2019-wepgw083
Proceedings IPAC\'19, 10th International Particle Accelerator Conference, Melbourne, Australia 2019-12-16
2019 A. Bertolet, A. Baratto‐Roldán, S. Barbieri, G. Baiocco, A. Carabe, M.A. Cortés‐Giraldo
Dose‐averaged LET calculation for proton track segments using microdosimetric Monte Carlo simulations
published pages: 4184-4192, ISSN: 0094-2405, DOI: 10.1002/mp.13643
Medical Physics 46/9 2019-12-16
2019 Theresa Werner, Jonathan Berthold, Fernando Hueso-González, Toni Koegler, Johannes Petzoldt, Katja Roemer, Christian Richter, Andreas Rinscheid, Arno Straessner, Wolfgang Enghardt, Guntram Pausch
Processing of prompt gamma-ray timing data for proton range measurements at a clinical beam delivery
published pages: 105023, ISSN: 1361-6560, DOI: 10.1088/1361-6560/ab176d
Physics in Medicine & Biology 64/10 2019-12-16
2019 D. Banon-Caballero, A. Vnuchenko, M. Boronat, N. Catalán Lasheras, A. Faus-Golfe, B. Gimeno, W. Wuensch et al.
Dark Current Analysis at CERN’s X-band Facility
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2019-weprb059
Proceedings IPAC\'19, 10th International Particle Accelerator Conference, Melbourne, Australia 2019-12-16
2017 R. Marco-Hernández, D. Alves, M.E. Angoletta, O. Marqversen, J. Molendijk, E. Oponowicz, R. Ruffieux, J. Sánchez-Quesada, L. SØby
The AD and ELENA orbit, trajectory and intensity measurement systems
published pages: P07024-P07024, ISSN: 1748-0221, DOI: 10.1088/1748-0221/12/07/p07024
Journal of Instrumentation 12/07 2019-12-16
2018 Y. Xie, J. Petzoldt, G. Janssens, L. Yin, E.H. Bentefour, J. Smeets, D. Prieels, R.L. Lustig, A. Lin, B.K. Teo
EP-1801: Prompt gamma imaging for the identification of proton range deviations due to anatomical change
published pages: S967-S968, ISSN: 0167-8140, DOI: 10.1016/s0167-8140(18)32110-8
Radiotherapy and Oncology 127 2019-12-16
2018 M. Volpi, M. Boland, C. Serpico, A. Vnuchenko, W. Wuensch et al.
High Power and High Repetition Rate X-band Power Source Using Multiple Klystrons
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2018-thpmk104
Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada 2019-12-16
2019 R. Schnuerer, J S.L. Yap, H. Zhang, T. Szumlak, T. Price and C.P. Welsch
Non-Invasive beam monitoring using LHCb VELO with 40 MeV protons
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2019-thpmp043
Proceedings IPAC\'19, 10th International Particle Accelerator Conference, Melbourne, Australia 2019-12-16
2018 N. Catalan-Lasheras, H. Damerau, R. Gerard, V. del Pozo Romano, A. Vnuchenko et al.
High Power Conditioning of X-Band RF Components
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2018-wepmf074
Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada 2019-12-16
2019 A. Bertolet, A. Baratto‐Roldán, M. A. Cortés‐Giraldo, A. Carabe‐Fernandez
Segment‐averaged LET concept and analytical calculation from microdosimetric quantities in proton radiation therapy
published pages: 4204-4214, ISSN: 0094-2405, DOI: 10.1002/mp.13673
Medical Physics 46/9 2019-12-16
2018 T. G. Lucas, M. Boland, A. Grudiev, A. Vnuchenko, W. Wuensch, R. Zennaro, et al.
Initial Testing of Techniques for Large Scale Rf Conditioning for the Compact Linear Collider
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2018-thpmk103
Proceedings IPAC’18, 9th International Particle Accelerator Conference, Vancouver, Canada 2019-12-16
2019 Felix Horst, Wihan Adi, Giulia Aricò, Kai-Thomas Brinkmann, Marco Durante, Claire-Anne Reidel, Marta Rovituso, Uli Weber, Hans-Georg Zaunick, Klemens Zink, Christoph Schuy
Measurement of PET isotope production cross sections for protons and carbon ions on carbon and oxygen targets for applications in particle therapy range verification
published pages: 205012, ISSN: 1361-6560, DOI: 10.1088/1361-6560/ab4511
Physics in Medicine & Biology 64/20 2019-12-16
2019 M P Carante, G Aricò, A Ferrari, W Kozlowska, A Mairani, F Ballarini
First benchmarking of the BIANCA model for cell survival prediction in a clinical hadron therapy scenario
published pages: 215008, ISSN: 1361-6560, DOI: 10.1088/1361-6560/ab490f
Physics in Medicine & Biology 64/21 2019-12-16
2017 A. Faus-Golfe, S. Barsuk, B. Borgo, D. Douillet, A. Vnuchenko et al.
First Optics Design and Beam Performance Simulation of PRAE: Platform for Research and Applications with Electrons at Orsay
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2017-thpva079
Proceedings IPAC’17, 8th International Particle Accelerator Conference, Copenhagen, Denmark 2019-12-16
2016 M. Fernandes, A. Lees, D. Alves, T. Koettig, E. Oponowicz, J. Tan, C. Welsch, R. Geithner, R. Neubert, T. Stöhlker, M. Schwickert
Optimized Cryogenic Current Comparator for CERN\'s Low-Energy Antiproton Facilities
published pages: , ISSN: , DOI: 10.18429/jacow-ibic2016-mopg48
Proceedings IBIC’16, 5th International Beam Instrumentation Conference, Barcelona, Spain 2019-12-16
2017 A. De Franco et al.
Upgrade Study of the MedAustron Ion Beam Center
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2017-thpva074
Proceedings IPAC’17, 8th International Particle Accelerator Conference, Copenhagen, Denmark 2019-12-16
2017 R. Schnuerer, J S.L. Yap, H. Zhang, C.P. Welsch
Non-Invasive beam monitoring using LHCb VELO
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2017-thpva1
Proceedings IPAC’17, 8th International Particle Accelerator Conference, Copenhagen, Denmark 2019-12-16
2017 E. Oponowicz, H. Owen
Superconducting Gantry Design for Proton Tomography
published pages: , ISSN: , DOI: 10.18429/jacow-ipac2017-thpva140
Proceedings IPAC’17, 8th International Particle Accelerator Conference, Copenhagen, Denmark 2019-12-16

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