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TwinnToInfect

Unleash IMM’s research excellence in immunity and infection through twinning to infect Lisbon and Portugal with its increase in competitiveness and innovation

Total Cost €

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EC-Contrib. €

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Project "TwinnToInfect" data sheet

The following table provides information about the project.

Coordinator
INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES 

Organization address
address: AVENIDA PROF EGAS MONIZ
city: LISBOA
postcode: 1649 028
website: www.imm.ul.pt

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Portugal [PT]
 Project website http://twinntoinfect.eu/
 Total cost 1˙000˙000 €
 EC max contribution 1˙000˙000 € (100%)
 Programme 1. H2020-EU.4.b. (Twinning of research institutions)
 Code Call H2020-TWINN-2015
 Funding Scheme CSA
 Starting year 2016
 Duration (year-month-day) from 2016-01-01   to  2018-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUTO DE MEDICINA MOLECULAR JOAO LOBO ANTUNES PT (LISBOA) coordinator 893˙500.00
2    INSTITUT PASTEUR FR (PARIS CEDEX 15) participant 53˙250.00
3    THE FRANCIS CRICK INSTITUTE LIMITED UK (LONDON) participant 53˙250.00

Map

 Project objective

TwinnToInfect will provide IMM with the opportunity to integrate the European circle of research excellence institutions by cementing a sustainable science, technology and innovation network with two internationally-leading organisations in the immunity and infection area of research, the Institut Pasteur and the Francis Crick Institute. The strategy of TwinnToInfect, based on science- and innovation-driven clustering, is focused on this societal challenge that lies at the centre of many age-related disorders. TwinnToInfect will allow: i. strengthening the science and technology capacity of IMM in immunity and infection research field; ii. and leverage its research excellence and value creation through innovation with a beneficial and quantifiable impact for the entire research and development community at IMM, the Lisbon region and Portugal. The successful implementation of this strategy will rely on specific actions, including: 1) cementing of existing and the creation of new scientific, innovative and technical collaborations through short-term staff exchanges and short-term on-site training activities; 2) training, mentoring and international exposure of IMM’s young researchers and students; 3) building an innovation ecosystem centred at IMM; 4) igniting the entrepreneurial spirit among IMM’s research community; 5) increasing science awareness among the general public through targeted dissemination and communication activities; and 6) developing a sustainability strategy to sustain the cemented network beyond project terminus. Through the completion of these activities, IMM, supported by Pasteur and Crick, is in the best temporal and spatial position to achieve an improved capability to compete for internationally competitive research funding and to access business stakeholders. By claiming its position in research and innovation networks IMM will effectively contribute to research excellence and value creation in health at European level.

 Deliverables

List of deliverables.
Second TwinnToInfect Joint Summer School Documents, reports 2019-10-02 12:51:19
First TwinnToInfect Joint Summer School Documents, reports 2019-10-02 12:51:19
EC KPI Widening indicator application for the 3-year window time prior to TwinnToInfect Documents, reports 2019-10-02 12:51:17
Communication package, including development of logo/brand, launch of website, brochure and flyer development Websites, patent fillings, videos etc. 2019-10-02 12:51:16
KPIs definition for TwinnToInfect Documents, reports 2019-10-02 12:51:16

Take a look to the deliverables list in detail:  detailed list of TwinnToInfect deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Duncan R. McKenzie, Iain Comerford, Bruno Silva-Santos, Shaun R. McColl
The Emerging Complexity of γδT17 Cells
published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.00796
Frontiers in Immunology 9 2019-10-02
2018 Bruno Silva-Santos, Jessica Strid
Working in “NK Mode”: Natural Killer Group 2 Member D and Natural Cytotoxicity Receptors in Stress-Surveillance by γδ T Cells
published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.00851
Frontiers in Immunology 9 2019-10-02
2016 Carolina Thieleke-Matos, Mafalda Lopes da Silva, Laura Cabrita-Santos, Martim D. Portal, Inês P. Rodrigues, Vanessa Zuzarte-Luis, José S. Ramalho, Clare E. Futter, Maria M. Mota, Duarte C. Barral, Miguel C. Seabra
Host cell autophagy contributes to Plasmodium liver development
published pages: 437-450, ISSN: 1462-5814, DOI: 10.1111/cmi.12524
Cellular Microbiology 18/3 2019-10-02
2017 Liliana Mancio-Silva, Ksenija Slavic, Margarida T. Grilo Ruivo, Ana Rita Grosso, Katarzyna K. Modrzynska, Iset Medina Vera, Joana Sales-Dias, Ana Rita Gomes, Cameron Ross MacPherson, Pierre Crozet, Mattia Adamo, Elena Baena-Gonzalez, Rita Tewari, Manuel Llinás, Oliver Billker, Maria M. Mota
Nutrient sensing modulates malaria parasite virulence
published pages: 213-216, ISSN: 0028-0836, DOI: 10.1038/nature23009
Nature 547/7662 2019-10-02
2018 Sandrina Nóbrega-Pereira, Francisco Caiado, Tânia Carvalho, Inês Matias, Gonçalo Graça, Luís G. Gonçalves, Bruno Silva-Santos, Haakan Norell, Sérgio Dias
VEGFR2–Mediated Reprogramming of Mitochondrial Metabolism Regulates the Sensitivity of Acute Myeloid Leukemia to Chemotherapy
published pages: 731-741, ISSN: 0008-5472, DOI: 10.1158/0008-5472.can-17-1166
Cancer Research 78/3 2019-10-02
2017 Cláudia Sá e Cunha, Britta Nyboer, Kirsten Heiss, Margarida Sanches-Vaz, Diana Fontinha, Ellen Wiedtke, Dirk Grimm, Jude Marek Przyborski, Maria M. Mota, Miguel Prudêncio, Ann-Kristin Mueller
Plasmodium berghei EXP-1 interacts with host Apolipoprotein H during Plasmodium liver-stage development
published pages: E1138-E1147, ISSN: 0027-8424, DOI: 10.1073/pnas.1606419114
Proceedings of the National Academy of Sciences 114/7 2019-10-02
2018 Maja Beus, Zrinka Rajić, Dusica Maysinger, Zvonimir Mlinarić, Maja Antunović, Inga Marijanović, Diana Fontinha, Miguel Prudêncio, Jana Held, Sureyya Olgen, Branka Zorc
SAHAquines, Novel Hybrids Based on SAHA and Primaquine Motifs, as Potential Cytostatic and Antiplasmodial Agents
published pages: 624-638, ISSN: 2191-1363, DOI: 10.1002/open.201800117
ChemistryOpen 7/8 2019-10-02
2016 Verena Brucklacher-Waldert, Cristina Ferreira, Silvia Innocentin, Shraddha Kamdar, David R. Withers, Marika C. Kullberg, Marc Veldhoen
Tbet or Continued RORγt Expression Is Not Required for Th17-Associated Immunopathology
published pages: 4893-4904, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1600137
The Journal of Immunology 196/12 2019-10-02
2016 David R Withers, Matthew R Hepworth, Xinxin Wang, Emma C Mackley, Emily E Halford, Emma E Dutton, Clare L Marriott, Verena Brucklacher-Waldert, Marc Veldhoen, Judith Kelsen, Robert N Baldassano, Gregory F Sonnenberg
Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells
published pages: 319-323, ISSN: 1078-8956, DOI: 10.1038/nm.4046
Nature Medicine 22/3 2019-10-02
2018 André E. Simões, Biagio Di Lorenzo, Bruno Silva-Santos
Molecular Determinants of Target Cell Recognition by Human γδ T Cells
published pages: , ISSN: 1664-3224, DOI: 10.3389/fimmu.2018.00929
Frontiers in Immunology 9 2019-10-02
2017 Kawaljit Singh, John Okombo, Christel Brunschwig, Ferdinand Ndubi, Linley Barnard, Chad Wilkinson, Peter M. Njogu, Mathew Njoroge, Lizahn Laing, Marta Machado, Miguel Prudêncio, Janette Reader, Mariette Botha, Sindisiwe Nondaba, Lyn-Marie Birkholtz, Sonja Lauterbach, Alisje Churchyard, Theresa L. Coetzer, Jeremy N. Burrows, Clive Yeates, Paolo Denti, Lubbe Wiesner, Timothy J. Egan, Sergio Wittlin, Kelly Chibale
Antimalarial Pyrido[1,2- a ]benzimidazoles: Lead Optimization, Parasite Life Cycle Stage Profile, Mechanistic Evaluation, Killing Kinetics, and in Vivo Oral Efficacy in a Mouse Model
published pages: 1432-1448, ISSN: 0022-2623, DOI: 10.1021/acs.jmedchem.6b01641
Journal of Medicinal Chemistry 60/4 2019-10-02
2018 Vanessa Zuzarte-Luís, Maria M. Mota
Parasite Sensing of Host Nutrients and Environmental Cues
published pages: 749-758, ISSN: 1931-3128, DOI: 10.1016/j.chom.2018.05.018
Cell Host & Microbe 23/6 2019-10-02
2016 Ricardo Ferraz, Joana Noronha, Fernanda Murtinheira, Fátima Nogueira, Marta Machado, Miguel Prudêncio, Silvia Parapini, Sarah D\'Alessandro, Cátia Teixeira, Ana Gomes, Cristina Prudêncio, Paula Gomes
Primaquine-based ionic liquids as a novel class of antimalarial hits
published pages: 56134-56138, ISSN: 2046-2069, DOI: 10.1039/c6ra10759a
RSC Advances 6/61 2019-10-02
2017 Taís S. Macedo, Wilmer Villarreal, Camila C. Couto, Diogo R. M. Moreira, Maribel Navarro, Marta Machado, Miguel Prudêncio, Alzir A. Batista, Milena B. P. Soares
Platinum( ii )–chloroquine complexes are antimalarial agents against blood and liver stages by impairing mitochondrial function
published pages: 1548-1561, ISSN: 1756-5901, DOI: 10.1039/c7mt00196g
Metallomics 9/11 2019-10-02
2018 Philippe Büscher, Jean-Mathieu Bart, Marleen Boelaert, Bruno Bucheton, Giuliano Cecchi, Nakul Chitnis, David Courtin, Luisa M. Figueiredo, José-Ramon Franco, Pascal Grébaut, Epco Hasker, Hamidou Ilboudo, Vincent Jamonneau, Mathurin Koffi, Veerle Lejon, Annette MacLeod, Justin Masumu, Enock Matovu, Raffaele Mattioli, Harry Noyes, Albert Picado, Kat S. Rock, Brice Rotureau, Gustave Simo, Sophie Thévenon, Sandra Trindade, Philippe Truc, Nick Van Reet
Do Cryptic Reservoirs Threaten Gambiense-Sleeping Sickness Elimination?
published pages: 197-207, ISSN: 1471-4922, DOI: 10.1016/j.pt.2017.11.008
Trends in Parasitology 34/3 2019-10-02
2018 Richard Staats, Raquel Rodrigues, André Barros, Leonor Bacelar-Nicolau, Margarida Aguiar, Dina Fernandes, Susana Moreira, André Simões, Bruno Silva-Santos, João Valença Rodrigues, Cristina Barbara, António Bugalho de Almeida, Luis Ferreira Moita
Decrease of perforin positive CD3+γδ-T cells in patients with obstructive sleep disordered breathing
published pages: 211-221, ISSN: 1520-9512, DOI: 10.1007/s11325-017-1602-6
Sleep and Breathing 22/1 2019-10-02
2017 Sérgio T. Ribeiro, João T. Barata, Bruno Silva-Santos
Multifaceted CK2 in malignant and healthy T cells
published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.21700
Oncotarget 8/53 2019-10-02
2018 Pedro H. Papotto, Bruno Silva-Santos
Got my γδ17 T cells to keep me warm
published pages: 427-429, ISSN: 1529-2908, DOI: 10.1038/s41590-018-0090-6
Nature Immunology 19/5 2019-10-02
2016 Carlos J.A. Ribeiro, Margarida Espadinha, Marta Machado, Jiri Gut, Lídia M. Gonçalves, Philip J. Rosenthal, Miguel Prudêncio, Rui Moreira, Maria M.M. Santos
Novel squaramides with in vitro liver stage antiplasmodial activity
published pages: 1786-1792, ISSN: 0968-0896, DOI: 10.1016/j.bmc.2016.03.005
Bioorganic & Medicinal Chemistry 24/8 2019-10-02
2017 Bruno Silva-Santos, Jessica Strid
γδ T cells get adaptive
published pages: 370-372, ISSN: 1529-2908, DOI: 10.1038/ni.3705
Nature Immunology 18/4 2019-10-02
2017 Marc Veldhoen
Th17 Cells Require You to Chew before You Swallow
published pages: 8-10, ISSN: 1074-7613, DOI: 10.1016/j.immuni.2016.12.016
Immunity 46/1 2019-10-02
2018 Vanessa Zuzarte-Luis, Maria M. Mota
Fighting for Resources: Who Started the Battle? Who Is Winning It?
published pages: 708-709, ISSN: 1550-4131, DOI: 10.1016/j.cmet.2018.03.007
Cell Metabolism 27/4 2019-10-02
2017 Herbert B. Tanowitz, Philipp E. Scherer, Maria M. Mota, Luisa M. Figueiredo
Adipose Tissue: A Safe Haven for Parasites?
published pages: 276-284, ISSN: 1471-4922, DOI: 10.1016/j.pt.2016.11.008
Trends in Parasitology 33/4 2019-10-02
2016 Zdenka Cicova, Mario Dejung, Tomas Skalicky, Nicole Eisenhuth, Steffen Hanselmann, Brooke Morriswood, Luisa M. Figueiredo, Falk Butter, Christian J. Janzen
Two flagellar BAR domain proteins in Trypanosoma brucei with stage-specific regulation
published pages: , ISSN: 2045-2322, DOI: 10.1038/srep35826
Scientific Reports 6/1 2019-10-02
2017 Agostinho Carvalho, Cláudio Duarte-Oliveira, Samuel M. Gonçalves, António Campos, João F. Lacerda, Cristina Cunha
Fungal Vaccines and Immunotherapeutics: Current Concepts and Future Challenges
published pages: 16-24, ISSN: 1936-3761, DOI: 10.1007/s12281-017-0272-y
Current Fungal Infection Reports 11/1 2019-10-02
2017 Cristina Cunha, Samuel M. Gonçalves, Cláudio Duarte-Oliveira, Luís Leite, Katrien Lagrou, António Marques, Carmen B. Lupiañez, Inês Mesquita, Joana Gaifem, Ana Margarida Barbosa, Carlos Pinho Vaz, Rosa Branca, Fernando Campilho, Fátima Freitas, Dário Ligeiro, Cornelia Lass-Flörl, Jürgen Löffler, Manuel Jurado, Margarida Saraiva, Oliver Kurzai, Fernando Rodrigues, António G. Castro, Ricardo Silvestre, Juan Sainz, Johan A. Maertens, Egídio Torrado, Ilse D. Jacobsen, João F. Lacerda, António Campos, Jr, Agostinho Carvalho
IL-10 overexpression predisposes to invasive aspergillosis by suppressing antifungal immunity
published pages: 867-870.e9, ISSN: 0091-6749, DOI: 10.1016/j.jaci.2017.02.034
Journal of Allergy and Clinical Immunology 140/3 2019-10-02
2018 Daniel P. Inácio, Tiago Amado, Bruno Silva-Santos, Anita Q. Gomes
Control of T cell effector functions by miRNAs
published pages: 63-73, ISSN: 0304-3835, DOI: 10.1016/j.canlet.2018.04.011
Cancer Letters 427 2019-10-02
2016 Miguel Muñoz-Ruiz, Julie C Ribot, Ana R Grosso, Natacha Gonçalves-Sousa, Ana Pamplona, Daniel J Pennington, José R Regueiro, Edgar Fernández-Malavé, Bruno Silva-Santos
TCR signal strength controls thymic differentiation of discrete proinflammatory γδ T cell subsets
published pages: 721-727, ISSN: 1529-2908, DOI: 10.1038/ni.3424
Nature Immunology 17/6 2019-10-02
2017 Filipa Rijo-Ferreira, Daniel Pinto-Neves, Nuno L. Barbosa-Morais, Joseph S. Takahashi, Luisa M. Figueiredo
Trypanosoma brucei metabolism is under circadian control
published pages: 17032, ISSN: 2058-5276, DOI: 10.1038/nmicrobiol.2017.32
Nature Microbiology 2 2019-10-02
2017 Patrícia Meireles, António M. Mendes, Rita I. Aroeira, Bryan C. Mounce, Marco Vignuzzi, Henry M. Staines, Miguel Prudêncio
Uptake and metabolism of arginine impact Plasmodium development in the liver
published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-04424-y
Scientific Reports 7/1 2019-10-02
2018 Marcela Šafratová, Anna Hošťálková, Daniela Hulcová, Kateřina Breiterová, Veronika Hrabcová, Marta Machado, Diana Fontinha, Miguel Prudêncio, Jiří Kuneš, Jakub Chlebek, Daniel Jun, Martina Hrabinová, Lucie Nováková, Radim Havelek, Martina Seifrtová, Lubomír Opletal, Lucie Cahlíková
Alkaloids from Narcissus poeticus cv. Pink Parasol of various structural types and their biological activity
published pages: 208-218, ISSN: 0253-6269, DOI: 10.1007/s12272-017-1000-4
Archives of Pharmacal Research 41/2 2019-10-02
2017 Patrícia Meireles, Joana Sales-Dias, Carolina M. Andrade, João Mello-Vieira, Liliana Mancio-Silva, J. Pedro Simas, Henry M. Staines, Miguel Prudêncio
GLUT1-mediated glucose uptake plays a crucial role during Plasmodium hepatic infection
published pages: e12646, ISSN: 1462-5814, DOI: 10.1111/cmi.12646
Cellular Microbiology 19/2 2019-10-02
2017 Gera Goverse, Rosalie Molenaar, Laurence Macia, Jian Tan, Martje N. Erkelens, Tanja Konijn, Marlene Knippenberg, Emma C. L. Cook, Diana Hanekamp, Marc Veldhoen, Anita Hartog, Guus Roeselers, Charles R. Mackay, Reina E. Mebius
Diet-Derived Short Chain Fatty Acids Stimulate Intestinal Epithelial Cells To Induce Mucosal Tolerogenic Dendritic Cells
published pages: 2172-2181, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1600165
The Journal of Immunology 198/5 2019-10-02
2016 S T Ribeiro, M Tesio, J C Ribot, E Macintyre, J T Barata, B Silva-Santos
Casein kinase 2 controls the survival of normal thymic and leukemic γδ T cells via promotion of AKT signaling
published pages: 1603-1610, ISSN: 0887-6924, DOI: 10.1038/leu.2016.363
Leukemia 31/7 2019-10-02
2016 Joana Barros-Martins, Nina Schmolka, Diana Fontinha, Marta Pires de Miranda, J. Pedro Simas, Ingrid Brok, Cristina Ferreira, Marc Veldhoen, Bruno Silva-Santos, Karine Serre
Effector γδ T Cell Differentiation Relies on Master but Not Auxiliary Th Cell Transcription Factors
published pages: 3642-3652, ISSN: 0022-1767, DOI: 10.4049/jimmunol.1501921
The Journal of Immunology 196/9 2019-10-02
2018 Pedro H. Papotto, Annika Reinhardt, Immo Prinz, Bruno Silva-Santos
Innately versatile: γδ17 T cells in inflammatory and autoimmune diseases
published pages: 26-37, ISSN: 0896-8411, DOI: 10.1016/j.jaut.2017.11.006
Journal of Autoimmunity 87 2019-10-02
2017 Shengyong Ng, Sandra March, Ani Galstian, Nil Gural, Kelly R. Stevens, Maria M. Mota, Sangeeta N. Bhatia
Towards a Humanized Mouse Model of Liver Stage Malaria Using Ectopic Artificial Livers
published pages: , ISSN: 2045-2322, DOI: 10.1038/srep45424
Scientific Reports 7/1 2019-10-02
2017 António M. Mendes, Inês S. Albuquerque, Marta Machado, Joana Pissarra, Patrícia Meireles, Miguel Prudêncio
Inhibition of Plasmodium liver infection by ivermectin
published pages: AAC.02005-16, ISSN: 0066-4804, DOI: 10.1128/aac.02005-16
Antimicrobial Agents and Chemotherapy 2019-10-02
2018 Marc Veldhoen, Birte Blankenhaus, Å pela Konjar, Cristina Ferreira
Metabolic wiring of murine T cell and intraepithelial lymphocyte maintenance and activation
published pages: 1430-1440, ISSN: 0014-2980, DOI: 10.1002/eji.201646745
European Journal of Immunology 48/9 2019-10-02
2017 Verena Brucklacher-Waldert, Cristina Ferreira, Marisa Stebegg, Olivier Fesneau, Silvia Innocentin, Julien C. Marie, Marc Veldhoen
Cellular Stress in the Context of an Inflammatory Environment Supports TGF-β-Independent T Helper-17 Differentiation
published pages: 2357-2370, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2017.05.052
Cell Reports 19/11 2019-10-02
2017 Biagio Di Lorenzo, Julie Déchanet-Merville, Bruno Silva-Santos
Peripheral clonal selection shapes the human γδ T-cell repertoire
published pages: 733-735, ISSN: 1672-7681, DOI: 10.1038/cmi.2017.51
Cellular & Molecular Immunology 14/9 2019-10-02
2018 Nina Schmolka, Pedro H. Papotto, Paula Vargas Romero, Tiago Amado, Francisco J. Enguita, Ana Amorim, Ana F. Rodrigues, Katrina E. Gordon, Ana S. Coroadinha, Mark Boldin, Karine Serre, Amy H. Buck, Anita Q. Gomes, Bruno Silva-Santos
MicroRNA-146a controls functional plasticity in γδ T cells by targeting NOD1
published pages: eaao1392, ISSN: 2470-9468, DOI: 10.1126/sciimmunol.aao1392
Science Immunology 3/23 2019-10-02
2018 Sofia Mensurado, Margarida Rei, Telma Lança, Marianna Ioannou, Natacha Gonçalves-Sousa, Hiroshi Kubo, Marie Malissen, Venizelos Papayannopoulos, Karine Serre, Bruno Silva-Santos
Tumor-associated neutrophils suppress pro-tumoral IL-17+ γδ T cells through induction of oxidative stress
published pages: e2004990, ISSN: 1545-7885, DOI: 10.1371/journal.pbio.2004990
PLOS Biology 16/5 2019-10-02
2017 Hiroshi Kubo, Sofia Mensurado, Natacha Gonçalves-Sousa, Karine Serre, Bruno Silva-Santos
Primary Tumors Limit Metastasis Formation through Induction of IL15-Mediated Cross-Talk between Patrolling Monocytes and NK Cells
published pages: 812-820, ISSN: 2326-6066, DOI: 10.1158/2326-6066.cir-17-0082
Cancer Immunology Research 5/9 2019-10-02
2016 Masahiro Hirakawa, Tiago Matos, Hongye Liu, John Koreth, Haesook T. Kim, Nicole E. Paul, Kazuyuki Murase, Jennifer Whangbo, Ana C. Alho, Sarah Nikiforow, Corey Cutler, Vincent T. Ho, Philippe Armand, Edwin P. Alyea, Joseph H. Antin, Bruce R. Blazar, Joao F. Lacerda, Robert J. Soiffer, Jerome Ritz
Low-dose IL-2 selectively activates subsets of CD4+ Tregs and NK cells
published pages: , ISSN: 2379-3708, DOI: 10.1172/jci.insight.89278
JCI Insight 1/18 2019-10-02
2018 Rita Capela, Joana Magalhães, Daniela Miranda, Marta Machado, Margarida Sanches-Vaz, Inês S. Albuquerque, Moni Sharma, Jiri Gut, Philip J. Rosenthal, Raquel Frade, Maria J. Perry, Rui Moreira, Miguel Prudêncio, Francisca Lopes
Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability
published pages: 69-78, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2018.02.048
European Journal of Medicinal Chemistry 149 2019-10-02
2018 Kristina Pavić, Ivana Perković, Šárka Pospíšilová, Marta Machado, Diana Fontinha, Miguel Prudêncio, Josef Jampilek, Aidan Coffey, Lorraine Endersen, Hrvoje Rimac, Branka Zorc
Primaquine hybrids as promising antimycobacterial and antimalarial agents
published pages: 769-779, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2017.11.083
European Journal of Medicinal Chemistry 143 2019-10-02
2016 Margarida T. Grilo Ruivo, Iset Medina Vera, Joana Sales-Dias, Patrícia Meireles, Nil Gural, Sangeeta N. Bhatia, Maria M. Mota, Liliana Mancio-Silva
Host AMPK Is a Modulator of Plasmodium Liver Infection
published pages: 2539-2545, ISSN: 2211-1247, DOI: 10.1016/j.celrep.2016.08.001
Cell Reports 16/10 2019-10-02
2016 Sandra Trindade, Filipa Rijo-Ferreira, Tânia Carvalho, Daniel Pinto-Neves, Fabien Guegan, Francisco Aresta-Branco, Fabio Bento, Simon A. Young, Andreia Pinto, Jan Van Den Abbeele, Ruy M. Ribeiro, Sérgio Dias, Terry K. Smith, Luisa M. Figueiredo
Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice
published pages: 837-848, ISSN: 1931-3128, DOI: 10.1016/j.chom.2016.05.002
Cell Host & Microbe 19/6 2019-10-02
2017 José Ferrão, Marisa Silva, Lúcia Gonçalves, Susana Gomes, Pedro Loureiro, Andreia Coelho, Armandina Miranda, Filomena Seuanes, Ana Batalha Reis, Francisca Pina, Raquel Maia, Paula Kjöllerström, Estela Monteiro, João F. Lacerda, João Lavinha, João Gonçalves, Paula Faustino
Widening the spectrum of deletions and molecular mechanisms underlying alpha-thalassemia
published pages: 1921-1929, ISSN: 0939-5555, DOI: 10.1007/s00277-017-3090-y
Annals of Hematology 96/11 2019-10-02
2018 Mark H. T. Stappers, Alexandra E. Clark, Vishukumar Aimanianda, Stefan Bidula, Delyth M. Reid, Patawee Asamaphan, Sarah E. Hardison, Ivy M. Dambuza, Isabel Valsecchi, Bernhard Kerscher, Anthony Plato, Carol A. Wallace, Raif Yuecel, Betty Hebecker, Maria da Glória Teixeira Sousa, Cristina Cunha, Yan Liu, Ten Feizi, Axel A. Brakhage, Kyung J. Kwon-Chung, Neil A. R. Gow, Matteo Zanda, Monica Piras, Chiara Zanato, Martin Jaeger, Mihai G. Netea, Frank L. van de Veerdonk, João F. Lacerda, António Campos, Agostinho Carvalho, Janet A. Willment, Jean-Paul Latgé, Gordon D. Brown
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus
published pages: 382-386, ISSN: 0028-0836, DOI: 10.1038/nature25974
Nature 555/7696 2019-10-02
2016 A. R. Almeida, D. V. Correia, A. Fernandes-Platzgummer, C. L. da Silva, M. G. da Silva, D. R. Anjos, B. Silva-Santos
Delta One T Cells for Immunotherapy of Chronic Lymphocytic Leukemia: Clinical-Grade Expansion/Differentiation and Preclinical Proof of Concept
published pages: 5795-5804, ISSN: 1078-0432, DOI: 10.1158/1078-0432.ccr-16-0597
Clinical Cancer Research 22/23 2019-10-02
2017 Augusto Ministro, Paula de Oliveira, Raquel J. Nunes, André dos Santos Rocha, Adriana Correia, Tânia Carvalho, José Rino, Pedro Faísca, Jorg D. Becker, João Goyri-O’Neill, Filomena Pina, Esmeralda Poli, Bruno Silva-Santos, Fausto Pinto, Marc Mareel, Karine Serre, Susana Constantino Rosa Santos
Low-dose ionizing radiation induces therapeutic neovascularization in a pre-clinical model of hindlimb ischemia
published pages: 783-794, ISSN: 0008-6363, DOI: 10.1093/cvr/cvx065
Cardiovascular Research 113/7 2019-10-02
2016 Maria M. Mota
Maria Mota: The Pleasure of Discovery
published pages: 429-430, ISSN: 1471-4922, DOI: 10.1016/j.pt.2016.01.003
Trends in Parasitology 32/6 2019-10-02
2017 Raquel Azevedo, Marija Markovic, Marta Machado, Blandine Franke-Fayard, António M. Mendes, Miguel Prudêncio
Bioluminescence Method for In Vitro Screening of Plasmodium Transmission-Blocking Compounds
published pages: , ISSN: 0066-4804, DOI: 10.1128/aac.02699-16
Antimicrobial Agents and Chemotherapy 61/6 2019-10-02
2016 Miguel A. S. Cavadas, Marco P. Monopoli, Cláudia Sá e Cunha, Miguel Prudêncio, Eulália Pereira, Iseult Lynch, Kenneth A. Dawson, Ricardo Franco
Unravelling Malaria Antigen Binding to Antibody-Gold Nanoparticle Conjugates
published pages: 906-915, ISSN: 0934-0866, DOI: 10.1002/ppsc.201600187
Particle & Particle Systems Characterization 33/12 2019-10-02
2016 Marta P. Carrasco, Marta Machado, Lídia Gonçalves, Moni Sharma, Jiri Gut, Amanda K. Lukens, Dyann F. Wirth, Vânia André, Maria Teresa Duarte, Rita C. Guedes, Daniel J. V. A. dos Santos, Philip J. Rosenthal, Ralph Mazitschek, Miguel Prudêncio, Rui Moreira
Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites
published pages: 2194-2204, ISSN: 1860-7179, DOI: 10.1002/cmdc.201600327
ChemMedChem 11/19 2019-10-02
2018 António M. Mendes, Marta Machado, Nataniel Gonçalves-Rosa, Isaie J. Reuling, Lander Foquet, Cláudia Marques, Ahmed M. Salman, Annie S. P. Yang, Kara A. Moser, Ankit Dwivedi, Cornelus C. Hermsen, Belén Jiménez-Díaz, Sara Viera, Jorge M. Santos, Inês Albuquerque, Sangeeta N. Bhatia, John Bial, Iñigo Angulo-Barturen, Joana C. Silva, Geert Leroux-Roels, Chris J. Janse, Shahid M. Khan, Maria M. Mota, Robert W. Sauerwein, Miguel Prudêncio
A Plasmodium berghei sporozoite-based vaccination platform against human malaria
published pages: , ISSN: 2059-0105, DOI: 10.1038/s41541-018-0068-2
npj Vaccines 3/1 2019-10-02
2017 Marta Machado, Margarida Sanches-Vaz, João P. Cruz, António M. Mendes, Miguel Prudêncio
Inhibition of Plasmodium Hepatic Infection by Antiretroviral Compounds
published pages: , ISSN: 2235-2988, DOI: 10.3389/fcimb.2017.00329
Frontiers in Cellular and Infection Microbiology 7 2019-10-02
2018 Rachel Fellows, Jérémy Denizot, Claudia Stellato, Alessandro Cuomo, Payal Jain, Elena Stoyanova, Szabina Balázsi, Zoltán Hajnády, Anke Liebert, Juri Kazakevych, Hector Blackburn, Renan Oliveira Corrêa, José Luís Fachi, Fabio Takeo Sato, Willian R. Ribeiro, Caroline Marcantonio Ferreira, Hélène Perée, Mariangela Spagnuolo, Raphaël Mattiuz, Csaba Matolcsi, Joana Guedes, Jonathan Clark, Marc Veldhoen, Tiziana Bonaldi, Marco Aurélio Ramirez Vinolo, Patrick Varga-Weisz
Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-02651-5
Nature Communications 9/1 2019-10-02
2016 Ana Henriques, Cláudia Silva, Mariana Santiago, Maria João Henriques, António Martinho, Hélder Trindade, José António Pereira da Silva, Bruno Silva-Santos, Artur Paiva
Subset-specific alterations in frequencies and functional signatures of γδ T cells in systemic sclerosis patients
published pages: 985-994, ISSN: 1023-3830, DOI: 10.1007/s00011-016-0982-6
Inflammation Research 65/12 2019-10-02
2018 Tânia Carvalho, Sandra Trindade, Sílvia Pimenta, Ana B. Santos, Filipa Rijo-Ferreira, Luísa M. Figueiredo
Trypanosoma brucei triggers a marked immune response in male reproductive organs
published pages: e0006690, ISSN: 1935-2735, DOI: 10.1371/journal.pntd.0006690
PLOS Neglected Tropical Diseases 12/8 2019-10-02
2016 TAÍS S. MACEDO, LEGNA COLINA-VEGAS, MARCELO DA PAIXÃO, MARIBEL NAVARRO, BRENO C. BARRETO, POLIANA C. M. OLIVEIRA, SIMONE G. MACAMBIRA, MARTA MACHADO, MIGUEL PRUDÊNCIO, SARAH D\'ALESSANDRO, NICOLETTA BASILICO, DIOGO R. M. MOREIRA, ALZIR A. BATISTA, MILENA B. P. SOARES
Chloroquine-containing organoruthenium complexes are fast-acting multistage antimalarial agents
published pages: 1543-1556, ISSN: 0031-1820, DOI: 10.1017/s0031182016001153
Parasitology 143/12 2019-10-02
2016 Ksenija Slavic, Sanjeev Krishna, Aparajita Lahree, Guillaume Bouyer, Kirsten K. Hanson, Iset Vera, Jon K. Pittman, Henry M. Staines, Maria M. Mota
A vacuolar iron-transporter homologue acts as a detoxifier in Plasmodium
published pages: , ISSN: 2041-1723, DOI: 10.1038/ncomms10403
Nature Communications 7/1 2019-10-02
2017 Andrea Cossarizza, Hyun-Dong Chang, Andreas Radbruch, Mübeccel Akdis, Immanuel Andrä, Francesco Annunziato, Petra Bacher, Vincenzo Barnaba, Luca Battistini, Wolfgang M. Bauer, Sabine Baumgart, Burkhard Becher, Wolfgang Beisker, Claudia Berek, Alfonso Blanco, Giovanna Borsellino, Philip E. Boulais, Ryan R. Brinkman, Martin Büscher, Dirk H. Busch, Timothy P. Bushnell, Xuetao Cao, Andrea Cavani, Pratip K. Chattopadhyay, Qingyu Cheng, Sue Chow, Mario Clerici, Anne Cooke, Antonio Cosma, Lorenzo Cosmi, Ana Cumano, Van Duc Dang, Derek Davies, Sara De Biasi, Genny Del Zotto, Silvia Della Bella, Paolo Dellabona, Günnur Deniz, Mark Dessing, Andreas Diefenbach, James Di Santo, Francesco Dieli, Andreas Dolf, Vera S. Donnenberg, Thomas Dörner, Götz R. A. Ehrhardt, Elmar Endl, Pablo Engel, Britta Engelhardt, Charlotte Esser, Bart Everts, Anita Dreher, Christine S. Falk, Todd A. Fehniger, Andrew Filby, Simon Fillatreau, Marie Follo, Irmgard Förster, John Foster, Gemma A. Foulds, Paul S. Frenette, David Galbraith, Natalio Garbi, Maria Dolores García-Godoy, Jens Geginat, Kamran Ghoreschi, Lara Gibellini, Christoph Goettlinger, Carl S. Goodyear, Andrea Gori, Jane Grogan, Mor Gross, Andreas Grützkau, Daryl Grummitt, Jonas Hahn, Quirin Hammer, Anja E. Hauser, David L. Haviland, David Hedley, Guadalupe Herrera, Martin Herrmann, Falk Hiepe, Tristan Holland, Pleun Hombrink, Jessica P. Houston, Bimba F. Hoyer, Bo Huang, Christopher A. Hunter, Anna Iannone, Hans-Martin Jäck, Beatriz Jávega, Stipan Jonjic, Kerstin Juelke, Steffen Jung, Toralf Kaiser, Tomas Kalina, Baerbel Keller, Srijit Khan, Deborah Kienhöfer, Thomas Kroneis, Désirée Kunkel, Christian Kurts, Pia Kvistborg, Joanne Lannigan, Olivier Lantz, Anis Larbi, Salome LeibundGut-Landmann, Michael D. Leipold, Megan K. Levings, Virginia Litwin, Yanling Liu, Michael Lohoff, Giovanna Lombardi, Lilly Lopez, Amy Lovett-Racke, Erik Lubberts, Burkhard Ludewig, Enrico Lugli, Holden T. Maecker, Glòria Martrus, Giuseppe Matarese, Christian Maueröder, Mairi McGrath, Iain McInnes, Henrik E. Mei, Fritz Melchers, Susanne Melzer, Dirk Mielenz, Kingston Mills, David Mirrer, Jenny Mjösberg, Jonni Moore, Barry Moran, Alessandro Moretta, Lorenzo Moretta, Tim R. Mosmann, Susann Müller, Werner Müller, Christian Münz, Gabriele Multhoff, Luis Enrique Munoz, Kenneth M. Murphy, Toshinori Nakayama, Milena Nasi, Christine Neudörfl, John Nolan, Sussan Nourshargh, José-Enrique O\'Connor, Wenjun Ouyang, Annette Oxenius, Raghav Palankar, Isabel Panse, Pärt Peterson, Christian Peth, Jordi Petriz, Daisy Philips, Winfried Pickl, Silvia Piconese, Marcello Pinti, A. Graham Pockley, Malgorzata Justyna Podolska, Carlo Pucillo, Sally A. Quataert, Timothy R. D. J. Radstake, Bartek Rajwa, Jonathan A. Rebhahn, Diether Recktenwald, Ester B.M. Remmerswaal, Katy Rezvani, Laura G. Rico, J. Paul Robinson, Chiara Romagnani, Anna Rubartelli, Beate Ruckert, Jürgen Ruland, Shimon Sakaguchi, Francisco Sala-de-Oyanguren, Yvonne Samstag, Sharon Sanderson, Birgit Sawitzki, Alexander Scheffold, Matthias Schiemann, Frank Schildberg, Esther Schimisky, Stephan A Schmid, Steffen Schmitt, Kilian Schober, Thomas Schüler, Axel Ronald Schulz, Ton Schumacher, Cristiano Scotta, T. Vincent Shankey, Anat Shemer, Anna-Katharina Simon, Josef Spidlen, Alan M. Stall, Regina Stark, Christina Stehle, Merle Stein, Tobit Steinmetz, Hannes Stockinger, Yousuke Takahama, Attila Tarnok, ZhiGang Tian, Gergely Toldi, Julia Tornack, Elisabetta Traggiai, Joe Trotter, Henning Ulrich, Marlous van der Braber, René A. W. van Lier, Marc Veldhoen, Salvador Vento-Asturias, Paulo Vieira, David Voehringer, Hans-Dieter Volk, Konrad von Volkmann, Ari Waisman, Rachael Walker, Michael D. Ward, Klaus Warnatz, Sarah Warth, James V. Watson, Carsten Watzl, Leonie Wegener, Annika Wiedemann, Jürgen Wienands, Gerald Willimsky, James Wing, Peter Wurst, Liping Yu, Alice Yue, Qianjun Zhang, Yi Zhao, Susanne Ziegler, Jakob Zimmermann
Guidelines for the use of flow cytometry and cell sorting in immunological studies
published pages: 1584-1797, ISSN: 0014-2980, DOI: 10.1002/eji.201646632
European Journal of Immunology 47/10 2019-10-02
2017 Marc Veldhoen
Interleukin 17 is a chief orchestrator of immunity
published pages: 612-621, ISSN: 1529-2908, DOI: 10.1038/ni.3742
Nature Immunology 18/6 2019-10-02
2018 Mark S. Gresnigt, Cristina Cunha, Martin Jaeger, Samuel M. Gonçalves, R. K. Subbarao Malireddi, Anne Ammerdorffer, Rosalie Lubbers, Marije Oosting, Orhan Rasid, Grégory Jouvion, Catherine Fitting, Dirk J. de Jong, João F. Lacerda, António Campos, Willem J. G. Melchers, Katrien Lagrou, Johan Maertens, Thirumala-Devi Kanneganti, Agostinho Carvalho, Oumaima Ibrahim-Granet, Frank L. van de Veerdonk
Genetic deficiency of NOD2 confers resistance to invasive aspergillosis
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-04912-3
Nature Communications 9/1 2019-10-02
2018 Filipa Rijo-Ferreira, Tânia Carvalho, Cristina Afonso, Margarida Sanches-Vaz, Rui M Costa, Luísa M. Figueiredo, Joseph S. Takahashi
Sleeping sickness is a circadian disorder
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-017-02484-2
Nature Communications 9/1 2019-10-02
2018 Irene Kyrmizi, Helena Ferreira, Agostinho Carvalho, Julio Alberto Landero Figueroa, Pavlos Zarmpas, Cristina Cunha, Tonia Akoumianaki, Kostas Stylianou, George S. Deepe, George Samonis, João F. Lacerda, António Campos, Dimitrios P. Kontoyiannis, Nikolaos Mihalopoulos, Kyung J. Kwon-Chung, Jamel El-Benna, Isabel Valsecchi, Anne Beauvais, Axel A. Brakhage, Nuno M. Neves, Jean-Paul Latge, Georgios Chamilos
Calcium sequestration by fungal melanin inhibits calcium–calmodulin signalling to prevent LC3-associated phagocytosis
published pages: 791-803, ISSN: 2058-5276, DOI: 10.1038/s41564-018-0167-x
Nature Microbiology 3/7 2019-10-02
2016 Bruno Silva-Santos, James Di Santo, Caetano Reis e Sousa
Immunology\'s Twinning Triangle
published pages: 2283-2285, ISSN: 0014-2980, DOI: 10.1002/eji.201670106
European Journal of Immunology 46/10 2019-10-02
2017 Pedro H Papotto, Natacha Gonçalves‐Sousa, Nina Schmolka, Andrea Iseppon, Sofia Mensurado, Brigitta Stockinger, Julie C Ribot, Bruno Silva‐Santos
IL‐23 drives differentiation of peripheral γδ17 T cells from adult bone marrow‐derived precursors
published pages: 1957-1967, ISSN: 1469-221X, DOI: 10.15252/embr.201744200
EMBO reports 18/11 2019-10-02
2016 A. C. Alho, H. T. Kim, M. J. Chammas, C. G. Reynolds, T. R. Matos, E. Forcade, J. Whangbo, S. Nikiforow, C. S. Cutler, J. Koreth, V. T. Ho, P. Armand, J. H. Antin, E. P. Alyea, J. F. Lacerda, R. J. Soiffer, J. Ritz
Unbalanced recovery of regulatory and effector T cells after allogeneic stem cell transplantation contributes to chronic GVHD
published pages: 646-657, ISSN: 0006-4971, DOI: 10.1182/blood-2015-10-672345
Blood 127/5 2019-10-02
2017 Miguel Muñoz-Ruiz, Nital Sumaria, Daniel J. Pennington, Bruno Silva-Santos
Thymic Determinants of γδ T Cell Differentiation
published pages: 336-344, ISSN: 1471-4906, DOI: 10.1016/j.it.2017.01.007
Trends in Immunology 38/5 2019-10-02

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "TWINNTOINFECT" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "TWINNTOINFECT" are provided by the European Opendata Portal: CORDIS opendata.

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