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Temporal mapping of environmental sensing transcription dynamics in Arabidopsis thaliana

Total Cost €


EC-Contrib. €






 plaNET-seq project word cloud

Explore the words cloud of the plaNET-seq project. It provides you a very rough idea of what is the project "plaNET-seq" about.

genomic    yield    interact    style    maps    biology    scientific    contemporary    reveal    solid    polymerase    capture    code    cold    question    competitiveness    understand    mediating    plant    temperatures    supervisor    environments    answers    abundant    nascent    regions    expertise    skills    events    strengthen    dynamics    proteins    organisms    dna    technologies    units    transcription    molecular    diversify    career    blueprint    researcher    independent    models    owing    promises    encouraging    regulation    characterise    blueprints    environmental    relatively    functional    cutting    academia    resolution    record    successful    act    infrastructure    temperature    environment    cues    transcripts    sessile    compensatory    coding    atmosphere    modern    action    life    pol    experts    predominantly    output    me    active    background    interaction    mysterious    hence    prepare    generate    nucleotide    track    unprecedented    degraded    maximise    rna    components    responsible    synergistically    largely    innovative    acclimation    favourably    single    plants    edge    host   

Project "plaNET-seq" data sheet

The following table provides information about the project.


Organization address
address: NORREGADE 10
postcode: 1165

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Denmark [DK]
 Project website
 Total cost 212˙194 €
 EC max contribution 212˙194 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-05-11   to  2019-09-20


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KOBENHAVNS UNIVERSITET DK (KOBENHAVN) coordinator 212˙194.00


 Project objective

A common challenge for all organisms is to interact favourably with their environments. The blueprint to do so is in their DNA. We understand relatively well DNA units that code for proteins but cutting-edge genomic technologies have identified predominantly non-coding regions that respond to environmental cues. Thus, how widespread non-coding transcription may be functional represents a key question in modern biology. My proposal addresses this topic by studying nascent transcription by RNA Polymerase II (Pol II) during plant environmental interaction. The novel and innovative approach promises unprecedented detail and down to single nucleotide resolution of active Pol II transcription dynamics in response to environmental cues. It will capture non-coding transcripts before they are degraded, enabling us to investigate the molecular events in largely mysterious yet abundant components of the genomic blueprints of life. Owing to their sessile life-style, plants are experts in mediating compensatory regulation to respond to the environment. Hence, they are particularly promising models to yield answers to this contemporary scientific question. A major interest of the action will be how plants respond to low temperature. I will generate genomic maps of Pol II in the act of transcription that will reveal the dynamics of transcription in response to low temperatures. In a targeted approach, I will identify and characterise the dynamics of coding and non-coding transcription in the genomic regions responsible for cold acclimation. My strong background and solid track record, the expertise and potential of the host supervisor together with the infrastructure and encouraging scientific atmosphere at the host department will synergistically contribute to maximise the output of the proposal. It will strengthen the competitiveness of Europe and develop and diversify my skills as an independent researcher and prepare me for a successful career within academia.


year authors and title journal last update
List of publications.
2019 Mathias Nielsen, Ryan Ard, Xueyuan Leng, Maxim Ivanov, Peter Kindgren, Vicent Pelechano, Sebastian Marquardt
Transcription-driven chromatin repression of Intragenic transcription start sites
published pages: e1007969, ISSN: 1553-7390, DOI: 10.1371/journal.pgen.1007969
PLOS Genetics 15/2 2020-02-27
2018 Peter Kindgren, Ryan Ard, Maxim Ivanov, Sebastian Marquardt
Transcriptional read-through of the long non-coding RNA SVALKA governs plant cold acclimation
published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-018-07010-6
Nature Communications 9/1 2020-02-27

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The information about "PLANET-SEQ" are provided by the European Opendata Portal: CORDIS opendata.

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