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FOIPO

Functional optical probes for otology

Total Cost €

0

EC-Contrib. €

0

Partnership

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 FOIPO project word cloud

Explore the words cloud of the FOIPO project. It provides you a very rough idea of what is the project "FOIPO" about.

validated    vibration    impede    demonstrated    thereby    vibrations    series    tomography    tympanic    vibrography    diagnosis    static    chain    functional    clinical    pico    losses    visualizing    signals    dynamic    electrical    simultaneously    events    membrane    disorders    globally    travel    excite    speed    structure    probe    operate    probes    infections    ex    sound    stimuli    people    technique    oscillations    designed    oct    miniaturized    operation    incus    quantifying    health    pathological    modes    diseases    motions    khz    canal    first    mode    middle    suffer    drum    acoustic    waves    frequency    flexible    surface    optical    biofilms    accurate    hearing    imaging    foundation    ossicular    various    conduction    displacement    optics    captured    stapes    primary    specimens    conductive    structures    treatments    frequencies    issue    worldwide    human    inner    tm    capturing    ear    air    malleus    prevalent    sounds    ing    360    nanometer    coupled    depends    coherence    speaker    time    eardrum    vivo    million    tissue    critical    rapid    termed    pathologies    portal   

Project "FOIPO" data sheet

The following table provides information about the project.

Coordinator
STICHTING VU 

Organization address
address: DE BOELELAAN 1105
city: AMSTERDAM
postcode: 1081 HV
website: www.vu.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2019-04-23

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VU NL (AMSTERDAM) coordinator 110˙760.00
2    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 66˙838.00

Map

 Project objective

Various pathologies directly impede the conduction of sound through the human middle ear, and thereby produce a ‘conductive’ hearing loss which is the second most prevalent health issue globally. According to Hearing Health Foundation more than 360 million people suffer from hearing disorders worldwide. Hearing depends on a series of events that change sound waves in the air into electrical signals. Sounds that travel down the ear canal set the surface of the flexible eardrum or tympanic membrane (TM) into rapid pico- to nanometer scale vibrations. These motions are coupled to the inner ear by the ossicular chain (the malleus, incus, and stapes). Since the TM and ossicular chain are the primary portal through which acoustic stimuli reach the inner ear, pathological changes in the TM or ossicular chain result in conductive hearing losses. Accurate diagnosis of middle-ear diseases is critical to effective and timely treatments of hearing loss. No currently available clinical technique is capable of simultaneously visualizing and quantifying the structure and sound-induced vibration of the middle ear in vivo. Recently, a new functional imaging technique based on optical coherence tomography (OCT) and the principle of vibrography for middle ear imaging was demonstrated. In this method, termed OCT-vibrography, a speaker is used to excite acoustic vibration in the tissue, and the resulting tissue displacement is captured by OCT. The goal of this project is to make for the first time a miniaturized OCT-vibrography probe for middle ear imaging at high frequencies. The miniaturized probe will be designed through integrated optics which will enable high-speed imaging. The system will operate in two modes: static imaging mode for examining biofilms and ear infections behind the ear drum; dynamic imaging mode for capturing high frequency (up to 20 kHz) oscillations in the middle ear structures. The operation of the miniaturized probes will be validated on ex vivo specimens.

 Publications

year authors and title journal last update
List of publications.
2018 B. Imran Akca
Integrated-optics Solutions for Biomedical Optical Imaging,
published pages: , ISSN: , DOI:
2020-01-20
2017 B. Imran Akca, N. Weiss, F. Coumans, and T. G van Leeuwen,
Integrated-optics based multi-beam imaging for speed improvement of OCT systems
published pages: , ISSN: , DOI:
Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 100560Q 2020-01-20
2018 Ton G. van Leeuwen, Imran B. Akca, Nikolaos Angelou, Nicolas Weiss, Marcel Hoekman, Arne Leinse, Rene G. Heideman
On-chip Mach-Zehnder interferometer for OCT systems
published pages: 103-106, ISSN: 2192-8584, DOI: 10.1515/aot-2017-0061
Advanced Optical Technologies 7/1-2 2020-01-20

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The information about "FOIPO" are provided by the European Opendata Portal: CORDIS opendata.

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