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FOIPO

Functional optical probes for otology

Total Cost €

0

EC-Contrib. €

0

Partnership

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 FOIPO project word cloud

Explore the words cloud of the FOIPO project. It provides you a very rough idea of what is the project "FOIPO" about.

membrane    signals    accurate    visualizing    speed    ex    pathological    incus    tissue    sounds    validated    optics    prevalent    conduction    motions    captured    worldwide    events    static    biofilms    health    conductive    middle    quantifying    surface    designed    vibrations    ear    optical    sound    oct    globally    khz    various    stimuli    vibration    flexible    thereby    human    million    frequencies    operation    miniaturized    oscillations    people    travel    functional    impede    tympanic    probes    suffer    acoustic    clinical    speaker    series    ing    depends    waves    electrical    displacement    primary    disorders    pathologies    structure    operate    stapes    hearing    demonstrated    termed    malleus    rapid    tm    first    canal    modes    probe    drum    inner    portal    vibrography    treatments    critical    issue    eardrum    chain    losses    air    imaging    coherence    coupled    infections    capturing    mode    structures    ossicular    vivo    technique    dynamic    diseases    tomography    frequency    nanometer    foundation    specimens    time    excite    simultaneously    diagnosis    360    pico   

Project "FOIPO" data sheet

The following table provides information about the project.

Coordinator
STICHTING VU 

Organization address
address: DE BOELELAAN 1105
city: AMSTERDAM
postcode: 1081 HV
website: www.vu.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2019-04-23

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VU NL (AMSTERDAM) coordinator 110˙760.00
2    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 66˙838.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Various pathologies directly impede the conduction of sound through the human middle ear, and thereby produce a ‘conductive’ hearing loss which is the second most prevalent health issue globally. According to Hearing Health Foundation more than 360 million people suffer from hearing disorders worldwide. Hearing depends on a series of events that change sound waves in the air into electrical signals. Sounds that travel down the ear canal set the surface of the flexible eardrum or tympanic membrane (TM) into rapid pico- to nanometer scale vibrations. These motions are coupled to the inner ear by the ossicular chain (the malleus, incus, and stapes). Since the TM and ossicular chain are the primary portal through which acoustic stimuli reach the inner ear, pathological changes in the TM or ossicular chain result in conductive hearing losses. Accurate diagnosis of middle-ear diseases is critical to effective and timely treatments of hearing loss. No currently available clinical technique is capable of simultaneously visualizing and quantifying the structure and sound-induced vibration of the middle ear in vivo. Recently, a new functional imaging technique based on optical coherence tomography (OCT) and the principle of vibrography for middle ear imaging was demonstrated. In this method, termed OCT-vibrography, a speaker is used to excite acoustic vibration in the tissue, and the resulting tissue displacement is captured by OCT. The goal of this project is to make for the first time a miniaturized OCT-vibrography probe for middle ear imaging at high frequencies. The miniaturized probe will be designed through integrated optics which will enable high-speed imaging. The system will operate in two modes: static imaging mode for examining biofilms and ear infections behind the ear drum; dynamic imaging mode for capturing high frequency (up to 20 kHz) oscillations in the middle ear structures. The operation of the miniaturized probes will be validated on ex vivo specimens.

 Publications

year authors and title journal last update
List of publications.
2018 B. Imran Akca
Integrated-optics Solutions for Biomedical Optical Imaging,
published pages: , ISSN: , DOI:
2020-01-20
2017 B. Imran Akca, N. Weiss, F. Coumans, and T. G van Leeuwen,
Integrated-optics based multi-beam imaging for speed improvement of OCT systems
published pages: , ISSN: , DOI:
Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 100560Q 2020-01-20
2018 Ton G. van Leeuwen, Imran B. Akca, Nikolaos Angelou, Nicolas Weiss, Marcel Hoekman, Arne Leinse, Rene G. Heideman
On-chip Mach-Zehnder interferometer for OCT systems
published pages: 103-106, ISSN: 2192-8584, DOI: 10.1515/aot-2017-0061
Advanced Optical Technologies 7/1-2 2020-01-20

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The information about "FOIPO" are provided by the European Opendata Portal: CORDIS opendata.

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