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FOIPO

Functional optical probes for otology

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 FOIPO project word cloud

Explore the words cloud of the FOIPO project. It provides you a very rough idea of what is the project "FOIPO" about.

critical    miniaturized    validated    frequency    worldwide    flexible    pico    time    human    portal    impede    electrical    disorders    health    surface    technique    vibration    prevalent    mode    tm    globally    ing    frequencies    chain    structure    rapid    coherence    thereby    sounds    probe    excite    drum    diagnosis    modes    eardrum    signals    issue    accurate    static    infections    capturing    diseases    tissue    travel    first    operate    speed    demonstrated    operation    million    imaging    middle    360    khz    tympanic    foundation    conductive    vibrography    vibrations    canal    tomography    pathological    speaker    stapes    primary    waves    ex    displacement    events    acoustic    designed    motions    malleus    incus    various    optics    clinical    treatments    optical    pathologies    termed    air    suffer    captured    specimens    functional    coupled    oct    quantifying    stimuli    nanometer    ear    series    dynamic    structures    sound    vivo    ossicular    probes    oscillations    simultaneously    losses    visualizing    hearing    conduction    biofilms    inner    membrane    depends    people   

Project "FOIPO" data sheet

The following table provides information about the project.

Coordinator
STICHTING VU 

Organization address
address: DE BOELELAAN 1105
city: AMSTERDAM
postcode: 1081 HV
website: www.vu.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 177˙598 €
 EC max contribution 177˙598 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2019-04-23

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    STICHTING VU NL (AMSTERDAM) coordinator 110˙760.00
2    ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM NL (AMSTERDAM) participant 66˙838.00

Map

 Project objective

Various pathologies directly impede the conduction of sound through the human middle ear, and thereby produce a ‘conductive’ hearing loss which is the second most prevalent health issue globally. According to Hearing Health Foundation more than 360 million people suffer from hearing disorders worldwide. Hearing depends on a series of events that change sound waves in the air into electrical signals. Sounds that travel down the ear canal set the surface of the flexible eardrum or tympanic membrane (TM) into rapid pico- to nanometer scale vibrations. These motions are coupled to the inner ear by the ossicular chain (the malleus, incus, and stapes). Since the TM and ossicular chain are the primary portal through which acoustic stimuli reach the inner ear, pathological changes in the TM or ossicular chain result in conductive hearing losses. Accurate diagnosis of middle-ear diseases is critical to effective and timely treatments of hearing loss. No currently available clinical technique is capable of simultaneously visualizing and quantifying the structure and sound-induced vibration of the middle ear in vivo. Recently, a new functional imaging technique based on optical coherence tomography (OCT) and the principle of vibrography for middle ear imaging was demonstrated. In this method, termed OCT-vibrography, a speaker is used to excite acoustic vibration in the tissue, and the resulting tissue displacement is captured by OCT. The goal of this project is to make for the first time a miniaturized OCT-vibrography probe for middle ear imaging at high frequencies. The miniaturized probe will be designed through integrated optics which will enable high-speed imaging. The system will operate in two modes: static imaging mode for examining biofilms and ear infections behind the ear drum; dynamic imaging mode for capturing high frequency (up to 20 kHz) oscillations in the middle ear structures. The operation of the miniaturized probes will be validated on ex vivo specimens.

 Publications

year authors and title journal last update
List of publications.
2018 B. Imran Akca
Integrated-optics Solutions for Biomedical Optical Imaging,
published pages: , ISSN: , DOI:
2020-01-20
2017 B. Imran Akca, N. Weiss, F. Coumans, and T. G van Leeuwen,
Integrated-optics based multi-beam imaging for speed improvement of OCT systems
published pages: , ISSN: , DOI:
Proc. SPIE 10056, Design and Quality for Biomedical Technologies X, 100560Q 2020-01-20
2018 Ton G. van Leeuwen, Imran B. Akca, Nikolaos Angelou, Nicolas Weiss, Marcel Hoekman, Arne Leinse, Rene G. Heideman
On-chip Mach-Zehnder interferometer for OCT systems
published pages: 103-106, ISSN: 2192-8584, DOI: 10.1515/aot-2017-0061
Advanced Optical Technologies 7/1-2 2020-01-20

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The information about "FOIPO" are provided by the European Opendata Portal: CORDIS opendata.

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