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Photoacoustic/Ultrasound Mammoscopy for evaluating screening-detected abnormalities in the breast

Total Cost €


EC-Contrib. €






Project "PAMMOTH" data sheet

The following table provides information about the project.


Organization address
postcode: 7522 NB

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 5˙105˙105 €
 EC max contribution 4˙352˙007 € (85%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2016-1
 Funding Scheme /RIA
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 864˙375.00
2    PA IMAGING R&D BV NL (ENSCHEDE) participant 816˙000.00
3    IMASONIC SAS FR (VORAY SUR L'OGNON) participant 760˙000.00
4    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 708˙663.00
5    EKSPLA UAB LT (VILNIUS) participant 410˙468.00
6    VYSOKE UCENI TECHNICKE V BRNE CZ (BRNO STRED) participant 385˙000.00
7    TP21 GMBH DE (BERLIN) participant 222˙500.00
9    UNIVERSITAET BERN CH (BERN) participant 0.00


 Project objective

X-ray mammography is the mainstay of breast cancer screening programs. It is estimated that between 20 - 50% of abnormal screening mammograms will prove to be negative. The paradigm in diagnosis is to establish whether a lesion is benign or malignant. All the imaging techniques conventionally used today – diagnostic x-ray, ultrasonography and magnetic resonance imaging have many limitations, leading to multiple and/or repeat imaging and often unnecessary biopsy. This leads to physical, psychological and economic burdens felt at individual, familial and societal levels.

With an aging population, high incidence of breast cancer and tightening health-care budgets, there is an urgent requirement for a non-invasive method for in-depth assessment of the screening-detected lesion. In PAMMOTH we will showcase such an imager, combining photoacoustic and ultrasound imaging. With the use of quantitative image reconstruction of multi-wavelength photoacoustic data, information is gained of the vascular and oxygen status of the lesion relating to tumor physiology and function. From the ultrasound part, we derive ultrasound reflection from the lesion in a manner superior to conventional breast ultrasonography, relating to anatomic features and extent of a tumor. This information will enable the radiologist to come to a diagnosis accurately and rapidly without the use of contrast agents, without pain and discomfort to the patient, while being cost-effective and not requiring complex infrastructure.

Four excellent academic groups, three dynamic SMEs, and a hospital come together with support from key stakeholders in an Advisory group, to push beyond the state-of-the-art in science and technology to achieve the PAMMOTH imager. For the SMEs, in addition to tremendous improvements in individual product lines, the new integrated diagnostic imaging instrument opens up completely new market opportunities.

We expect PAMMOTH to have a strong economic and clinical impact.

 Work performed, outcomes and results:  advancements report(s) 

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The information about "PAMMOTH" are provided by the European Opendata Portal: CORDIS opendata.

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