Opendata, web and dolomites

SIMULTAN SIGNED

Aging-related changes in brain activation and deactivation during cognition: novel insights into the physiology of the human mind from simultaneous PET-fMRI imaging

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 SIMULTAN project word cloud

Explore the words cloud of the SIMULTAN project. It provides you a very rough idea of what is the project "SIMULTAN" about.

healthy    positron    basis    tomography    scans    metabolic    examples    made    blood    vary    complexities    person    first    consistently    rely    reflects    monitor    resonance    resolved    physiological    metabolism    synaptic    modalities    deactivations    disentangle    pet    prompt    deactivation    hybrid    activation    emission    primarily    interplay    doubt    magnetic    demands    invariant    fmri    mental    functional    performance    flow    signals    adults    neurobiological    human    imaging    correlation    hemodynamic    gained    older    prefrontal    investigation    structured    complementary    sequential    clinical    time    there    distinguish    cognitive    younger    biology    mind    patterns    function    certain    contributions    found    stages    breakthrough    had    aging    brain    glucose    hemodynamics    normally    stems    designed    simultaneous    questions    disease    signal    individuals    rooted    mr    switches    invasive    packages    interpretation    alone    understand    molecular    led   

Project "SIMULTAN" data sheet

The following table provides information about the project.

Coordinator
UMEA UNIVERSITET 

Organization address
address: UNIVERSITETOMRADET
city: UMEA
postcode: 901 87
website: www.umu.se

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Sweden [SE]
 Total cost 1˙499˙544 €
 EC max contribution 1˙499˙544 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2016-STG
 Funding Scheme ERC-STG
 Starting year 2017
 Duration (year-month-day) from 2017-06-01   to  2022-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UMEA UNIVERSITET SE (UMEA) coordinator 1˙499˙544.00

Map

 Project objective

There is no doubt that functional magnetic resonance imaging (fMRI) has led to a breakthrough in our ability to measure how the complexities of the mind are rooted in biology. However, deactivation of certain brain areas during cognitive control and increased activation of prefrontal areas in aging are two examples of consistently found patterns of fMRI activation that have had a large impact on the study of the human mind, but that prompt major questions of interpretation. The physiological basis of the fMRI signal reflects interplay between hemodynamics and metabolic demands that vary across the brain, as well as between different tasks and individuals, and cannot be resolved by fMRI alone. To be able to use non-invasive imaging to distinguish a normally aging brain from one that is in the pre-clinical stages of disease, it is important to understand the neurobiological basis of these functional brain changes. Positron emission tomography (PET) is a molecular imaging method that is able to monitor brain glucose metabolism, which stems primarily from synaptic activity and is invariant to changes in blood flow. Studies that have made use of the complementary information gained from fMRI and PET to investigate human brain function have had to rely on sequential scans, and correlation of the signals from both modalities between individuals. The investigation of within-person switches between different mental states with complementary modalities is only made possible by the recent development of a hybrid PET-MR system, which, for the first time, allows simultaneous assessment of fMRI signal, blood flow and PET glucose metabolism during cognitive task performance. The proposal is structured in three work packages that include PET-fMRI scans in 30 healthy younger and 40 older adults. The analyses are designed to disentangle the hemodynamic and metabolic contributions to fMRI deactivations and prefrontal over-activation in aging during cognitive task performance.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SIMULTAN" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SIMULTAN" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.1.)

MuFLOART (2018)

Microbiological fluorescence observatory for antibiotic resistance tracking

Read More  

HyperBio (2019)

Vis-NIR Hyperspectral imaging for biomaterial quality control

Read More  

MiniEmbryoBlueprint (2019)

The mammalian body plan blueprint, an in vitro approach

Read More