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Pre-commercial lines for production of surface nanostructured antimicrobial and anti-biofilm textiles, medical devices and water treatment membranes

Total Cost €


EC-Contrib. €






 PROTECT project word cloud

Explore the words cloud of the PROTECT project. It provides you a very rough idea of what is the project "PROTECT" about.

characterization    ppy    biocompatible    efficiency    safety    nanoparticles    biologicals    nanocoating    routes    point    roll    functional    medical    time    enzymes    antibacterial    hybrid    successful    cover    public    fsls    membranes    antimicrobial    pln    adhesive    polypyrrole    spray    pilots    obtain    protect    cuxzn1    xo    network    effectiveness    polymer    introduce    sono    market    anti    implementing    manufacturing    surfaces    reproducible    incorporating    antibacterials    sustainability    inorganic    quality    emanated    water    sonochemical    labs    antibiofilm    implantable    finish    textiles    reproducibility    characterise    fast    hospitals    coating    nanostructured    novo    lines    robustness    dots    upgrade    pilot    monitoring    relation    batch    embedding    starting    treatment    introducing    lipids    specialty    platform    thermo    ga    nano    training    fp7    si    capacity    bioelectricsurface    nanoscale    uses    coated    biofilm    composite    technologies    lab    functionalized    polymeric    comprising    materials    preventing    r2r    tio2    categories    nps   

Project "PROTECT" data sheet

The following table provides information about the project.


Organization address
postcode: 8034

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website
 Total cost 9˙441˙862 €
 EC max contribution 7˙478˙985 € (79%)
 Programme 1. H2020-EU.2.1.2. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Nanotechnologies)
 Code Call H2020-NMBP-PILOTS-2016
 Funding Scheme IA
 Starting year 2017
 Duration (year-month-day) from 2017-01-01   to  2020-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
2    BAR ILAN UNIVERSITY IL (RAMAT GAN) participant 680˙125.00
4    INDATECH SAS FR (CLAPIERS) participant 543˙637.00
5    I.C.O.N.E. FR (NOYAREY) participant 500˙500.00
6    CEDRAT TECHNOLOGIES SA FR (MEYLAN) participant 490˙525.00
7    Klopman International Srl IT (FROSINONE) participant 436˙310.00
11    DEGANIA SILICONE LTD IL (KIBBUTZ DEGANIA B) participant 366˙100.00
12    OSM-DAN LTD IL (REHOVOT) participant 337˙575.00
15    MAROCO, LDA PT (PACOS DE FERREIRA) participant 219˙056.00
16    UNIVERSITY OF LIMERICK IE (LIMERICK) participant 179˙156.00
18    FONTE NUOVA SRL IT (GRAVINA DI CATANIA) participant 86˙187.00
19    NSC - NANO SONO COOPERATION LTD IL (YOKNEAM) participant 86˙187.00
20    TESSITURA PERTILE SRL IT (CHIERI TO) participant 85˙050.00
21    Kessler ProData GmbH DE (Reutlingen) participant 39˙511.00
23    SYNTHAUR OOO RU (MOSKVA) participant 0.00


 Project objective

PROTECT aims to introduce to the market One step antimicrobial finish processes for polymeric materials used in i) specialty textiles for public areas and hospitals, ii) water treatment membranes, and iii) implantable medical devices. Compared to main existing manufacturing routes, the proposed one-step coating technologies are simple, fast, and reproducible. For this, PROTECT uses as a starting point four existing pilot lines emanated from high successful FP7 projects SONO, NOVO and BioElectricSurface. PROTECT will upgrade the nanocoating One step process platform comprising: two roll to roll (R2R) pilots (sonochemical and spray coating) for functional textiles production, a R2R thermo-embedding pilot for antibacterial/biofilm preventing water treatment membranes, and a batch sonochemical pilot for antibacterial/antibiofilm/biocompatible medical devices. This platform will cover a wide range of applications due to their specific characteristics by the following objectives: a) Incorporating ‘antibacterial antibiofilm biocompatible novel nanoparticles’(NPs) of the following categories: inorganic (CuxZn1-xO ,5 Ga@C-dots, Si/TiO2 composite) polymer (polypyrrole, PPy)) and biologicals (antibacterial enzymes, functionalized lipids (FSLs), hybrid antibacterials) to obtain ‘biocompatible nanostructured surfaces with antimicrobial and anti-adhesive’ properties. b) Implementing real time characterization methods for monitoring at the nanoscale to characterise relevant materials, process properties and product features for ‘real-time nanoscale characterization’ to ensure ‘reproducibility’ and ‘quality’ of the nano-coated products c) Improving ‘coating efficiency, production capacity, reproducibility, robustness, cost-effectiveness, safety and sustainability’ of the processes in relation to the targeted applications. d) Introducing a Labs Network (PLN) that will include also lab scale processes of the proposed technologies for ‘training and knowledge dissemination.


List of deliverables.
Report on the assembled pre-commercial coating lines at the industrial premises of the partners Documents, reports 2020-02-12 17:17:38
Project brochure addressing the pre-commercial lines and associated products Websites, patent fillings, videos etc. 2020-02-12 17:18:56
Report on the smart metabolic sensing for functional life time monitoring of the end products Documents, reports 2020-02-12 17:17:40
Report on the establishment of the PROTECT PLN including a brochure to detail technologies, services and prices Documents, reports 2020-02-12 17:17:37
Report on the hazard determinants for the environment safety profile of the new processes and end products Documents, reports 2020-02-12 17:17:36
First report and demonstration of real time monitoring by the PBI of the NPs size, concentration and coating uniformity of the end product Documents, reports 2020-02-12 17:17:36
Final Report on the metabolic sensing for functional life time monitoring of the end products Documents, reports 2020-02-12 17:17:40
Public Project website Websites, patent fillings, videos etc. 2019-10-15 16:54:09
Report on the LCC and LCA of the three coating processes and recommendation for improvements based on inputs from the existing pilots Documents, reports 2019-10-15 16:54:08
Plan for using and disseminating the Know-how Documents, reports 2019-10-15 16:54:08
First Report on Safety by Process Design implementation for the coating processes Documents, reports 2019-10-15 16:54:08
Staff exchange plan between SMEs and R&D centres Documents, reports 2019-10-15 16:54:08

Take a look to the deliverables list in detail:  detailed list of PROTECT deliverables.


year authors and title journal last update
List of publications.
2020 Irini Furxhi, Finbarr Murphy, Martin Mullins, Athanasios Arvanitis, Craig A. Poland
Nanotoxicology data for in silico tools: a literature review
published pages: 1-26, ISSN: 1743-5390, DOI: 10.1080/17435390.2020.1729439
Nanotoxicology 2020-03-05
2020 Simona Ortelli, Anna Luisa Costa
Insulating Thermal and Water-Resistant Hybrid Coating for Fabrics
published pages: 72, ISSN: 2079-6412, DOI: 10.3390/coatings10010072
Coatings 10/1 2020-02-18
2019 M. Blanes, M. Martínez, A. Romero, M. Canet, F. Fernández, O. Calvo
Application of antibacterial textile finishes by sonochemistry and its characterization
published pages: , ISSN: , DOI:
44 Symposium 2019, AEQCT 6th, March 2019 2020-02-05
2019 Ivanova A., Ivanova K., Heinze T., Tzanov T.,
Safe-by-design hybrid nanoparticles of antimicrobial silver, aminocellulose, and quorum quenching acylase eradicate bacteria and their biofilms
published pages: , ISSN: , DOI:
257th American Chemical Society National Meeting & Exposition 31 March – 4 April 2019 2020-02-05
2019 257th American Chemical Society National Meeting & Exposition. G., Ivanova K., Bassegoda A., Torrent-Burgués J., Tzanov T
Metal-protein nanocomposites with bactericidal and antibiofilm efficacies
published pages: , ISSN: , DOI:
257th American Chemical Society National Meeting & Exposition. 31 March – 4 April 2019 2020-02-05
2019 Hoyo J., Tzanov T
Antimicrobial functionalization of cotton textiles with ZnO NPs and gallic acid embedded in an in-situ sono-enzymatically generated bioadhesive
published pages: , ISSN: , DOI:
257th American Chemical Society National Meeting & Exposition 31 March – 4 April 2019 2020-02-05
2019 Hoyo J., Ivanova K., Guaus E., Tzanov T
Single-step hybrid nanocoating on contact lenses to face associated conditions and discomfort
published pages: , ISSN: , DOI:
257th American Chemical Society National Meeting & Exposition 31 March – 4 April 2019 2020-02-05
2019 Javier Hoyo, Kristina Ivanova, Ester Guaus, Tzanko Tzanov
Multifunctional ZnO NPs-chitosan-gallic acid hybrid nanocoating to overcome contact lenses associated conditions and discomfort
published pages: 114-121, ISSN: 0021-9797, DOI: 10.1016/j.jcis.2019.02.043
Journal of Colloid and Interface Science 543 2020-01-30
2019 Simona Ortelli, et. al.,
Monitoring occupational exposure scenarios during the production of nanostructured antibacterial textiles
published pages: , ISSN: , DOI:
Nanoinnovation2019 11-14 June 2019 2020-01-30
2019 Felice C. Simeone, et. al
Managing occupational safety issues of nanomaterials in manufacturing processes
published pages: , ISSN: , DOI:
Nanoinnovation2019 11-14 June 2019 2020-01-30
2019 Anjani P. Nagvenkar, Ilana Perelshtein, Ylenia Piunno, Paride Mantecca, Aharon Gedanken
Sonochemical One-Step Synthesis of Polymer-Capped Metal Oxide Nanocolloids: Antibacterial Activity and Cytotoxicity
published pages: 13631-13639, ISSN: 2470-1343, DOI: 10.1021/acsomega.9b00181
ACS Omega 4/9 2020-01-30
2019 Zerboni, Bengalli, Baeri, Fiandra, Catelani, Mantecca
Mixture Effects of Diesel Exhaust and Metal Oxide Nanoparticles in Human Lung A549 Cells
published pages: 1302, ISSN: 2079-4991, DOI: 10.3390/nano9091302
Nanomaterials 9/9 2020-01-30
2020 Luisa Fiandra, Patrizia Bonfanti, Ylenia Piunno, Anjani P. Nagvenkar, Ilana Perlesthein, Aharon Gedanken, Melissa Saibene, Anita Colombo, Paride Mantecca
Hazard assessment of polymer-capped CuO and ZnO nanocolloids: A contribution to the safe-by-design implementation of biocidal agents
published pages: 100195, ISSN: 2452-0748, DOI: 10.1016/j.impact.2019.100195
NanoImpact 17 2020-01-30
2019 Graziano Colombo, Cristina Cortinovis, Elisa Moschini, Nicholas Bellitto, Maria Chiara Perego, Marco Albonico, Emanuela Astori, Isabella Dalle‐Donne, Alessia Bertero, Aharon Gedanken, Ilana Perelsthein, Paride Mantecca, Francesca Caloni
Cytotoxic and proinflammatory responses induced by ZnO nanoparticles in in vitro intestinal barrier
published pages: , ISSN: 0260-437X, DOI: 10.1002/jat.3800
Journal of Applied Toxicology 2019-10-15
2017 M. Díaz-González, G. Boix, C. Fernández-Sánchez, A. Bald
Wax microfluidics light-addressable valve with multiple actuation
published pages: , ISSN: , DOI:
SPIE Micro-technologies Conference, 8-10 May 2017 8-10 May, 2017 2019-10-15
2017 Paride Mantecca, Kaja Kasemets, Archana Deokar, Ilana Perelshtein, Aharon Gedanken, Yeon Kyoung Bahk, Baharh Kianfar, Jing Wang
Airborne Nanoparticle Release and Toxicological Risk from Metal-Oxide-Coated Textiles: Toward a Multiscale Safe-by-Design Approach
published pages: 9305-9317, ISSN: 0013-936X, DOI: 10.1021/acs.est.7b02390
Environmental Science & Technology 51/16 2019-10-15
2017 Kristina Ivanova, Eva Ramon, Javier Hoyo, Tzanko Tzanov
Innovative Approaches for Controlling Clinically Relevant Biofilms: Current Trends and Future Prospects
published pages: 1889-1914, ISSN: 1568-0266, DOI: 10.2174/1568026617666170105143315
Current Topics in Medicinal Chemistry 17/17 2019-10-15
2017 Ivanova K, Hoyo J, Tzanov T.
Hybrid nano-antibacterials to control biofilm-associated infections
published pages: , ISSN: , DOI:
253rd American Chemical Society National Meeting & Exposition 2-6 April, 2017 2019-10-15
2017 Tzanov T, Ivanova K
Pilots for production of surface nano-structured antimicrobial and anti-biofilm materials
published pages: , ISSN: , DOI:
Polymer Replication on Nanoscale, 4th International Conference 8-9 May, 2017 2019-10-15
2018 Arnau Bassegoda, Kristina Ivanova, Eva Ramon, Tzanko Tzanov
Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials
published pages: 2075-2089, ISSN: 0175-7598, DOI: 10.1007/s00253-018-8776-0
Applied Microbiology and Biotechnology 102/5 2019-10-15
2018 Marc Salat, Petya Petkova, Javier Hoyo, Ilana Perelshtein, Aharon Gedanken, Tzanko Tzanov
Durable antimicrobial cotton textiles coated sonochemically with ZnO nanoparticles embedded in an in-situ enzymatically generated bioadhesive
published pages: 198-203, ISSN: 0144-8617, DOI: 10.1016/j.carbpol.2018.02.033
Carbohydrate Polymers 189 2019-10-15
2017 Antonio Francesko, Marta Cano Fossas, Petya Petkova, Margarida M. Fernandes, Ernest Mendoza, Tzanko Tzanov
Sonochemical synthesis and stabilization of concentrated antimicrobial silver-chitosan nanoparticle dispersions
published pages: 45136, ISSN: 0021-8995, DOI: 10.1002/app.45136
Journal of Applied Polymer Science 134/30 2019-10-15
2018 Barry Sheehan, Finbarr Murphy, Martin Mullins, Irini Furxhi, Anna Costa, Felice Simeone, Paride Mantecca
Hazard Screening Methods for Nanomaterials: A Comparative Study
published pages: 649, ISSN: 1422-0067, DOI: 10.3390/ijms19030649
International Journal of Molecular Sciences 19/3 2019-10-15
2017 Antonio Andretta; Giuseppe Rosace; Alessio Varesano; Massimo Perucca
Industrial innovation and market opportunities for nano-enabled textiles
published pages: , ISSN: , DOI:
Nano Innovation 2017 26-29 September, 2017 2019-10-15
2017 Carla Silva
Antibacterial Textiles by spray US
published pages: , ISSN: , DOI:
iTechStyle Summit - 1st International Conference of Textile and Clothing 13-14 February, 2017 2019-10-15
2017 P. Manteca
Nanotoxicology meets the industry: the safe-by-design approach
published pages: , ISSN: , DOI:
MECSPE, Tecnologie per l’Innovazione, Industria 4.0 23-25 March, 2017 2019-10-15
2017 Margarida M. Fernandes, Kristina Ivanova, Javier Hoyo, Sílvia Pérez-Rafael, Antonio Francesko, Tzanko Tzanov
Nanotransformation of Vancomycin Overcomes the Intrinsic Resistance of Gram-Negative Bacteria
published pages: 15022-15030, ISSN: 1944-8244, DOI: 10.1021/acsami.7b00217
ACS Applied Materials & Interfaces 9/17 2019-10-15
2017 A. Gedanken
Making the Hospital a Safer Place by the Sonochemical Coating of all the Textiles and Other Medical Devices with Antibacterial nanoparticle
published pages: , ISSN: , DOI:
6th Conference on Nanomaterials (CN 2017) 3-5 January, 2017 2019-10-15
2017 Finbarr Murphy, Martin Mullins, Karena Hester, Allen Gelwick, Janeck J. Scott-Fordsmand, Trevor Maynard
Insuring nanotech requires effective risk communication
published pages: 717-719, ISSN: 1748-3387, DOI: 10.1038/nnano.2017.162
Nature Nanotechnology 12/8 2019-10-15
2017 A. Gedanken
Making the Hospital a Safer Place by Coating of all its Textiles with Antibacterial Nanoparticles
published pages: , ISSN: , DOI:
NanoWorld Conference 3-5 April, 2017 2019-10-15
2017 Lina Vanesa Garcia Peña, Petya Petkova, Rosanna Margalef-Marti, Marc Vives, Lorena Aguilar, Angel Gallegos, Antonio Francesko, Ilana Perelshtein, Aharon Gedanken, Ernest Mendoza, Juan Carlos Casas-Zapata, Jordi Morató, Tzanko Tzanov
Hybrid Chitosan–Silver Nanoparticles Enzymatically Embedded on Cork Filter Material for Water Disinfection
published pages: 3599-3606, ISSN: 0888-5885, DOI: 10.1021/acs.iecr.6b04721
Industrial & Engineering Chemistry Research 56/13 2019-10-15
2018 Rasel Das, Bey Fen Leo, Finbarr Murphy
The Toxic Truth About Carbon Nanotubes in Water Purification: a Perspective View
published pages: , ISSN: 1931-7573, DOI: 10.1186/s11671-018-2589-z
Nanoscale Research Letters 13/1 2019-10-15
2019 Irini Furxhi, Finbarr Murphy, Martin Mullins, Craig A. Poland
Machine learning prediction of nanoparticle in vitro toxicity: A comparative study of classifiers and ensemble-classifiers using the Copeland Index
published pages: 157-166, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2019.05.016
Toxicology Letters 312 2019-10-15
2019 Irini Furxhi, Finbarr Murphy, Craig A. Poland, Barry Sheehan, Martin Mullins, Paride Mantecca
Application of Bayesian networks in determining nanoparticle-induced cellular outcomes using transcriptomics
published pages: 1-22, ISSN: 1743-5390, DOI: 10.1080/17435390.2019.1595206
Nanotoxicology 2019-10-15
2019 Felice C. Simeone, Magda Blosi, Simona Ortelli, Anna L. Costa
Assessing occupational risk in designs of production processes of nano-materials
published pages: 100149, ISSN: 2452-0748, DOI: 10.1016/j.impact.2019.100149
NanoImpact 14 2019-10-15
2019 Diego Omar Sanchez Ramirez, Alessio Varesano, Riccardo Andrea Carletto, Claudia Vineis, Ilana Perelshtein, Michal Natan, Nina Perkas, Ehud Banin, Aharon Gedanken
Antibacterial properties of polypyrrole-treated fabrics by ultrasound deposition
published pages: 164-170, ISSN: 0928-4931, DOI: 10.1016/j.msec.2019.04.016
Materials Science and Engineering: C 102 2019-10-15
2018 A. Zerboni, P. Mantecca
Toxicity of DEP and metal oxide nanoparticles mixtures in human lung cells
published pages: S236-S237, ISSN: 0378-4274, DOI: 10.1016/j.toxlet.2018.06.987
Toxicology Letters 295 2019-10-15
2017 A. Varesano, C. Vineis, C. Tonetti, D. Omar S. Ramirez, R.A. Carletto
Natural and polypyrrole-based antibacterial finishing of textiles
published pages: , ISSN: , DOI:
Nano Innovation 2017 26-29 September 2017 2019-10-15
2017 A. Varesano, C. Vineis, D.O. Sanchez Ramirez
Novel antibacterial polymer-based finishing for textiles
published pages: , ISSN: , DOI:
MECSPE, Tecnologie per l\'innovazione, Industria 4.0 23-25 March 2017 2019-10-15

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The information about "PROTECT" are provided by the European Opendata Portal: CORDIS opendata.

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