Opendata, web and dolomites

OMICS TERMINATED

Origami-based Microfluidic Interface for Cell Signalling

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

Project "OMICS" data sheet

The following table provides information about the project.

Coordinator
KARLSRUHER INSTITUT FUER TECHNOLOGIE 

Organization address
address: KAISERSTRASSE 12
city: KARLSRUHE
postcode: 76131
website: www.kit.edu

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Germany [DE]
 Project website https://carmenmd87.wixsite.com/omicsmsca
 Total cost 159˙460 €
 EC max contribution 159˙460 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2016
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2017
 Duration (year-month-day) from 2017-03-15   to  2019-03-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    KARLSRUHER INSTITUT FUER TECHNOLOGIE DE (KARLSRUHE) coordinator 159˙460.00

Map

 Project objective

Cell surface receptors react to a multitude of signal molecules that trigger cellular responses and regulate cell fate. The malfunction of receptors and signals in cells may lead to the development of many diseases, including cancer, diabetes, neurodegeneration or autoimmune disorders. Thus, understanding complex signal pathways is key for future therapeutic approaches and drug development.

This project concerns the development of a high throughput microfluidic device for the investigation of early cell signalling, which is triggered by ligand-decorated DNA origami nanostructures, immobilized on a microarray-patterned surface inside the microfluidic device. By combining state-of-the-art top-down microstructuring and bottom-up self-assembly, this approach allows to present ligands on surfaces with a full control of their absolute number, stoichiometry and nanoscale orientation, enabling to closer mimic the natural cell environment. While the principal functioning of origami-based ligand presentation has very recently been demonstrated by the beneficiary, the here proposed implementation in a microfluidic chip will improve surface stability and robustness, as well as allow automated, on-surface assembly and cell culture processes to open the door to multiplexing and high throughput analyses.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "OMICS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "OMICS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

NaWaTL (2020)

Narrative, Writing, and the Teotihuacan Language: Exploring Language History Through Phylogenetics, Epigraphy and Iconography

Read More  

TGL (2019)

Transition Governance and Law

Read More  

WATCH (2019)

Wessex–Armorica: Territories, Connections and Hierarchies

Read More