Explore the words cloud of the InPhoTime project. It provides you a very rough idea of what is the project "InPhoTime" about.
The following table provides information about the project.
Biologicke centrum AV CR, v. v. i.
|Coordinator Country||Czech Republic [CZ]|
|Total cost||2˙000˙000 €|
|EC max contribution||2˙000˙000 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2017-04-01 to 2022-03-31|
Take a look of project's partnership.
|1||Biologicke centrum AV CR, v. v. i.||CZ (CESKE BUDEJOVICE)||coordinator||2˙000˙000.00|
Daylength measuring devices such as the photoperiodic timer enable animals to anticipate and thus survive adverse seasons. This ability has contributed to the great success of insects living in temperate regions. Yet the basis of photoperiodic sensing remains elusive, because of the lack of suitable genetic models expressing photoperiod-dependent seasonal phenotypes. We have developed the linden bug, Pyrrhocoris apterus, into a genetically tractable model with a robust, photoperiod-dependent reproductive arrest (diapause). With the available tools, this insect has become ideal for deciphering the regulation of seasonality. The project has 3 clear and ambitious objectives: 1). Our goal is to define the molecular and anatomical bases of the photoperiodic timer. To achieve this, we propose to identify photoperiodic timer genes, genes regulating input to the timer, and early output markers, through an RNA interference screen(s). To define the molecular mechanism of the timer, we will employ genome editing to precisely alter properties of the key players. 2). Next, we will combine techniques of neuronal backfilling, in-vivo fluorescent reporters, and microsurgery to define the photoperiodic timer anatomically and to examine its spatial relationship to the circadian clock in the insect brain. 3). We will exploit the great natural geographic variability of photoperiodic timing in P. apterus to explore its genetic basis. Genetic variants correlating with phenotypic differences will be causally tested by genome editing within the original genetic backgrounds. Both the established and the innovative strategies provide a complementary approach to the first molecular characterization of the seasonal photoperiodic timer in insects. The proposed research aspires to explain mechanisms underlying the critical physiological adaptation to changing seasons. Deciphering mechanisms underpinning widespread adaptation might bring general implications for environment-friendly pest control.
|year||authors and title||journal||last update|
Joanna Kotwica-Rolinska, Lenka Chodakova, Daniela Chvalova, Lucie Kristofova, Iva Fenclova, Jan Provaznik, Maly Bertolutti, Bulah Chia-Hsiang Wu, David Dolezel
CRISPR/Cas9 Genome Editing Introduction and Optimization in the Non-model Insect Pyrrhocoris apterus
published pages: , ISSN: 1664-042X, DOI: 10.3389/fphys.2019.00891
|Frontiers in Physiology 10||2020-02-13|
Samarjeet Singh, Astrid Giesecke, Milena Damulewicz, Silvie Fexova, Gabriella M. Mazzotta, Ralf Stanewsky, David Dolezel
New Drosophila Circadian Clock Mutants Affecting Temperature Compensation Induced by Targeted Mutagenesis of Timeless
published pages: , ISSN: 1664-042X, DOI: 10.3389/fphys.2019.01442
|Frontiers in Physiology 10||2020-02-13|
TomÃ¡Å¡ Ditrich, VÃ¡clav Janda, Hana VanÄ›ÄkovÃ¡, David DoleÅ¾el
Climatic Variation of Supercooling Point in the Linden Bug Pyrrhocoris apterus (Heteroptera: Pyrrhocoridae)
published pages: 144, ISSN: 2075-4450, DOI: 10.3390/insects9040144
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "INPHOTIME" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "INPHOTIME" are provided by the European Opendata Portal: CORDIS opendata.