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iDESIGN SIGNED

Delivering Better Starting Points for Drug Discovery: New Compound Libraries Driven By Intelligent Design

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 iDESIGN project word cloud

Explore the words cloud of the iDESIGN project. It provides you a very rough idea of what is the project "iDESIGN" about.

reduce    instrumentation    scientists    whilst    proportion    full    oversee    researcher    return    training    advantage    drugs    professionals    consummate    thesis    expert    difficult    begin    months    spirit    sectors    birmingham    companies    molecules    rates    points    pharma    hit    compound    molecular    therapeutics    individual    synthetic    expertise    esrs    silico    acquiring    populating    see    chemists    final    starting    quality    entrepreneurial    employment    designed    scaffolds    library    complete    drug    discovery    combining    generation    innovators    diverse    smaller    business    attrition    complementary    communicators    medicinal    principal    academic    stages    structurally    campaigns    generate    transfer    experimental    supervisors    smart    screening    time    creative    skills    libraries    identification    phd    confident    idesign    blight    efficient    bespoke    flexible    synthesis    elaborate    industrial    preparation    never    validate   

Project "iDESIGN" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF BIRMINGHAM 

Organization address
address: Edgbaston
city: BIRMINGHAM
postcode: B15 2TT
website: www.bham.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 1˙565˙180 €
 EC max contribution 1˙565˙180 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-EID
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) coordinator 622˙489.00
2    MERCACHEM BV NL (NIJMEGEN) participant 624˙248.00
3    AnalytiCon Discovery GmbH DE (Potsdam) participant 318˙443.00
4    Apconix UK (Alderley) partner 0.00
5    MERCALEADS BV NL (NIJMEGEN) partner 0.00
6    MERCATORIAL BV NL (NIJMEGEN) partner 0.00

Map

 Project objective

Whilst the need to generate new therapeutics has never been more important, drug discovery is at the same time becoming much more difficult. In short, we need to be more efficient at developing drugs. One way of achieving this is to reduce the attrition rates, which currently blight the drug-discovery process, by populating compound screening libraries with more structurally diverse and higher quality, i.e. designed, molecules to provide better starting points for drug development. Pharma also needs a new type of researcher given an increasing proportion of scientists are now finding employment in smaller companies, where they need to be more flexible, entrepreneurial and business-aware. iDESIGN seeks to address these key challenges by combining the complementary expertise from both academic and industrial sectors. iDESIGN has the following Principal Objectives: 1) to use the ESRs' individual research projects to develop new, structurally diverse, 'smart' compound libraries for the sector to use in hit-identification screening campaigns; 2) to provide a training programme which will see the ESRs becoming expert synthetic and medicinal chemists, confident research scientists, consummate professionals, effective communicators and innovators with a creative and entrepreneurial spirit. iDESIGN will begin with an academic training phase, during which the ESRs will undertake project-wide training whilst acquiring the synthesis skills to generate bespoke molecular scaffolds, which they will elaborate and validate using in silico and experimental methods. The ESRs will then transfer to one of the industrial partners to take full advantage of their Industrial Supervisors' expertise and the available instrumentation to complete the library-generation aspect of their research projects. All 6 ESRs will return to Birmingham for their final 2 months to allow their Academic Supervisors to oversee directly the final stages of their PhD thesis preparation.

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The information about "IDESIGN" are provided by the European Opendata Portal: CORDIS opendata.

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