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iDESIGN SIGNED

Delivering Better Starting Points for Drug Discovery: New Compound Libraries Driven By Intelligent Design

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 iDESIGN project word cloud

Explore the words cloud of the iDESIGN project. It provides you a very rough idea of what is the project "iDESIGN" about.

experimental    generate    preparation    combining    attrition    individual    consummate    expertise    drug    therapeutics    points    difficult    silico    supervisors    synthetic    companies    esrs    birmingham    final    libraries    generation    innovators    blight    business    stages    industrial    return    drugs    rates    months    full    discovery    pharma    medicinal    proportion    academic    smaller    screening    scientists    molecular    researcher    time    see    scaffolds    designed    flexible    acquiring    principal    whilst    advantage    creative    smart    populating    skills    complete    hit    entrepreneurial    synthesis    phd    chemists    never    transfer    spirit    complementary    identification    elaborate    idesign    confident    efficient    library    professionals    begin    thesis    reduce    molecules    validate    starting    expert    oversee    compound    instrumentation    quality    employment    communicators    training    campaigns    structurally    sectors    bespoke    diverse   

Project "iDESIGN" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF BIRMINGHAM 

Organization address
address: Edgbaston
city: BIRMINGHAM
postcode: B15 2TT
website: www.bham.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 1˙565˙180 €
 EC max contribution 1˙565˙180 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-EID
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) coordinator 622˙489.00
2    MERCACHEM BV NL (NIJMEGEN) participant 624˙248.00
3    AnalytiCon Discovery GmbH DE (Potsdam) participant 318˙443.00
4    Apconix UK (Alderley) partner 0.00
5    MERCALEADS BV NL (NIJMEGEN) partner 0.00
6    MERCATORIAL BV NL (NIJMEGEN) partner 0.00

Map

 Project objective

Whilst the need to generate new therapeutics has never been more important, drug discovery is at the same time becoming much more difficult. In short, we need to be more efficient at developing drugs. One way of achieving this is to reduce the attrition rates, which currently blight the drug-discovery process, by populating compound screening libraries with more structurally diverse and higher quality, i.e. designed, molecules to provide better starting points for drug development. Pharma also needs a new type of researcher given an increasing proportion of scientists are now finding employment in smaller companies, where they need to be more flexible, entrepreneurial and business-aware. iDESIGN seeks to address these key challenges by combining the complementary expertise from both academic and industrial sectors. iDESIGN has the following Principal Objectives: 1) to use the ESRs' individual research projects to develop new, structurally diverse, 'smart' compound libraries for the sector to use in hit-identification screening campaigns; 2) to provide a training programme which will see the ESRs becoming expert synthetic and medicinal chemists, confident research scientists, consummate professionals, effective communicators and innovators with a creative and entrepreneurial spirit. iDESIGN will begin with an academic training phase, during which the ESRs will undertake project-wide training whilst acquiring the synthesis skills to generate bespoke molecular scaffolds, which they will elaborate and validate using in silico and experimental methods. The ESRs will then transfer to one of the industrial partners to take full advantage of their Industrial Supervisors' expertise and the available instrumentation to complete the library-generation aspect of their research projects. All 6 ESRs will return to Birmingham for their final 2 months to allow their Academic Supervisors to oversee directly the final stages of their PhD thesis preparation.

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The information about "IDESIGN" are provided by the European Opendata Portal: CORDIS opendata.

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