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iDESIGN SIGNED

Delivering Better Starting Points for Drug Discovery: New Compound Libraries Driven By Intelligent Design

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 iDESIGN project word cloud

Explore the words cloud of the iDESIGN project. It provides you a very rough idea of what is the project "iDESIGN" about.

smart    business    whilst    designed    researcher    idesign    complete    principal    preparation    consummate    time    employment    molecules    starting    compound    flexible    academic    professionals    populating    spirit    esrs    diverse    points    full    blight    scaffolds    chemists    structurally    molecular    transfer    expertise    validate    silico    thesis    efficient    smaller    phd    hit    companies    never    instrumentation    begin    innovators    medicinal    individual    expert    elaborate    communicators    quality    campaigns    library    discovery    training    acquiring    confident    synthesis    generation    libraries    bespoke    screening    return    oversee    drugs    stages    supervisors    see    scientists    months    attrition    industrial    generate    entrepreneurial    pharma    skills    complementary    creative    final    birmingham    combining    therapeutics    advantage    synthetic    drug    rates    sectors    proportion    reduce    identification    difficult    experimental   

Project "iDESIGN" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF BIRMINGHAM 

Organization address
address: Edgbaston
city: BIRMINGHAM
postcode: B15 2TT
website: www.bham.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Total cost 1˙565˙180 €
 EC max contribution 1˙565˙180 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2017
 Funding Scheme MSCA-ITN-EID
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF BIRMINGHAM UK (BIRMINGHAM) coordinator 622˙489.00
2    MERCACHEM BV NL (NIJMEGEN) participant 624˙248.00
3    AnalytiCon Discovery GmbH DE (Potsdam) participant 318˙443.00
4    Apconix UK (Alderley) partner 0.00
5    MERCALEADS BV NL (NIJMEGEN) partner 0.00
6    MERCATORIAL BV NL (NIJMEGEN) partner 0.00

Map

 Project objective

Whilst the need to generate new therapeutics has never been more important, drug discovery is at the same time becoming much more difficult. In short, we need to be more efficient at developing drugs. One way of achieving this is to reduce the attrition rates, which currently blight the drug-discovery process, by populating compound screening libraries with more structurally diverse and higher quality, i.e. designed, molecules to provide better starting points for drug development. Pharma also needs a new type of researcher given an increasing proportion of scientists are now finding employment in smaller companies, where they need to be more flexible, entrepreneurial and business-aware. iDESIGN seeks to address these key challenges by combining the complementary expertise from both academic and industrial sectors. iDESIGN has the following Principal Objectives: 1) to use the ESRs' individual research projects to develop new, structurally diverse, 'smart' compound libraries for the sector to use in hit-identification screening campaigns; 2) to provide a training programme which will see the ESRs becoming expert synthetic and medicinal chemists, confident research scientists, consummate professionals, effective communicators and innovators with a creative and entrepreneurial spirit. iDESIGN will begin with an academic training phase, during which the ESRs will undertake project-wide training whilst acquiring the synthesis skills to generate bespoke molecular scaffolds, which they will elaborate and validate using in silico and experimental methods. The ESRs will then transfer to one of the industrial partners to take full advantage of their Industrial Supervisors' expertise and the available instrumentation to complete the library-generation aspect of their research projects. All 6 ESRs will return to Birmingham for their final 2 months to allow their Academic Supervisors to oversee directly the final stages of their PhD thesis preparation.

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The information about "IDESIGN" are provided by the European Opendata Portal: CORDIS opendata.

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