Explore the words cloud of the EU-TRAIN project. It provides you a very rough idea of what is the project "EU-TRAIN" about.
The following table provides information about the project.
Coordinator |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Organization address contact info |
Coordinator Country | France [FR] |
Total cost | 6˙641˙546 € |
EC max contribution | 6˙641˙546 € (100%) |
Programme |
1. H2020-EU.3.1.1. (Understanding health, wellbeing and disease) |
Code Call | H2020-SC1-2017-Two-Stage-RTD |
Funding Scheme | RIA |
Starting year | 2018 |
Duration (year-month-day) | from 2018-01-01 to 2022-12-31 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE | FR (PARIS) | coordinator | 1˙025˙447.00 |
2 | CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES | FR (NANTES) | participant | 1˙207˙741.00 |
3 | ASSISTANCE PUBLIQUE HOPITAUX DE PARIS | FR (PARIS) | participant | 1˙154˙520.00 |
4 | CHARITE - UNIVERSITAETSMEDIZIN BERLIN | DE (BERLIN) | participant | 898˙236.00 |
5 | INSTITUT CATALA DE LA SALUT | ES (BARCELONA) | participant | 750˙597.00 |
6 | UNIVERSITE DE GENEVE | CH (GENEVE) | participant | 444˙413.00 |
7 | INSERM TRANSFERT SA | FR (PARIS) | participant | 391˙875.00 |
8 | OXFORD IMMUNOTEC LIMITED | UK (ABINGDON) | participant | 303˙841.00 |
9 | CELLTREND GESELLSCHAFT MIT BESCHRANKTER HAFTUNG | DE (LUCKENWALDE) | participant | 208˙313.00 |
10 | EUROPEAN SOCIETY FOR ORGAN TRANSPLANTATION | NL (AMSTERDAM) | participant | 120˙000.00 |
11 | CERNER FRANCE | FR (PUTEAUX) | participant | 96˙563.00 |
12 | ECRIN EUROPEAN CLINICAL RESEARCH INFRASTRUCTURE NETWORK | FR (PARIS) | participant | 40˙000.00 |
Rejection is the major cause of allograft failure with dramatic consequences in terms of mortality, morbidity and increased cost for the society. The field of transplantation lacks a robust assessment of risk stratification. Thus, it impairs the development of relevant clinical trials to address graft and patient outcomes. We formed the EU-TRAIN project by gathering reference kidney transplant centres in a fully operating European network including 12 partners. Our ambitious but realistic goals are: to provide clinicians with innovative and accessible tools for early prediction of individual risk of allograft rejection and transplant loss; to personalise clinical management and treatment and; to improve allograft outcomes. This project will engineer a risk stratification system applied to kidney transplant patients by analysing the integration of several layers of data (clinical, histological, immunological data as well as gene expression and novel biomarkers) - the TRAnsplant Comprehensive Evaluator of Risk (EU-TRACER). EU-TRACER will be generated and validated in 2 dedicated studies including a randomised control trial. Translation to patients will be achieved by delivering: 1) A multiplex non-invasive biomarker system for the stratification and immune monitoring of low and high risk kidney recipients; 2) A prognostic system for individual risk stratification for allograft rejection and failure that will assist decision making via an interactive web interface. The EU-TRACER, developed with our 3 industrial partners, will define a new standard of care in transplantation. The EU-TRACER will have the potential for a large implementation and diffusion in other centres in Europe and will be suitable for industrial collaboration.
Communication and Dissemination tools | Websites, patent fillings, videos etc. | 2020-04-07 22:49:49 |
Take a look to the deliverables list in detail: detailed list of EU-TRAIN deliverables.
year | authors and title | journal | last update |
---|---|---|---|
2019 |
Nuria Montero, Samira Farouk, Ilaria Gandolfini, Elena Crespo, Marta Jarque, Maria Meneghini, Alba Torija, Umberto Maggiore, Paolo Cravedi, Oriol Bestard Pretransplant Donor-specific IFNγ ELISPOT as a Predictor of Graft Rejection published pages: e451, ISSN: 2373-8731, DOI: 10.1097/txd.0000000000000886 |
Transplantation Direct 5/5 | 2020-04-07 |
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The information about "EU-TRAIN" are provided by the European Opendata Portal: CORDIS opendata.
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