Explore the words cloud of the MAXIBONE project. It provides you a very rough idea of what is the project "MAXIBONE" about.
The following table provides information about the project.
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
|Coordinator Country||France [FR]|
|Total cost||5˙975˙915 €|
|EC max contribution||5˙949˙665 € (100%)|
1. H2020-EU.3.1.3. (Treating and managing disease)
|Duration (year-month-day)||from 2018-01-01 to 2021-12-31|
Take a look of project's partnership.
|1||INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE||FR (PARIS)||coordinator||812˙287.00|
|2||ETABLISSEMENT FRANCAIS DU SANG||FR (LA PLAINE SAINT DENIS)||participant||1˙552˙938.00|
|3||UNIVERSITAET ULM||DE (ULM)||participant||1˙382˙173.00|
|4||UNIVERSITETET I BERGEN||NO (BERGEN)||participant||812˙239.00|
|5||MIMETIS BIOMATERIALS SL||ES (CERDANYOLA DEL VALLES BARCELONA)||participant||320˙596.00|
|6||SYDDANSK UNIVERSITET||DK (ODENSE M)||participant||302˙800.00|
|7||SORLANDET SYKEHUS HF||NO (KRISTIANSAND S)||participant||167˙125.00|
|8||CENTRE HOSPITALIER UNIVERSITAIRE DE NANTES||FR (NANTES)||participant||160˙781.00|
|9||UNIVERSIDAD COMPLUTENSE DE MADRID||ES (MADRID)||participant||157˙128.00|
|10||ASSISTANCE PUBLIQUE HOPITAUX DE PARIS||FR (PARIS)||participant||142˙062.00|
|11||UNIVERSITAT INTERNACIONAL DE CATALUNYA||ES (BARCELONA)||participant||139˙531.00|
|12||INSTITUT STRAUMANN AG||CH (BASEL)||participant||0.00|
Several tens of millions of European citizens are partially edentulous and have insufficient bone for placement of dental implants. Following FP7 REBORNE project on bone regeneration, the MAXIBONE consortium coordinated by INSERM wishes to perform a randomized controlled clinical trial on alveolar ridge augmentation in mandibular and maxillary bone. This late stage clinical trial will aim at comparing the safety and efficacy of autologous bone grafting (gold standard) with culture expanded autologous bone marrow mesenchymal stem cells (MSCs) associated to a synthetic bone substitute covered by a resorbable membrane in 150 patients. The recruitment will be performed in 10 major hospital centres while the production of MSC will be done in the German and French blood transfusion institutes. Medical imaging, direct measurements and histology of core biopsies before dental implants will ensure the evaluation of bone regeneration. Cost-effective monitoring using a secured internet platform (eCRF) will produce a clinical database for evaluation of safety, efficacy and health costs in both arms. The participation of the innovative biomaterial SME Mimetis and the industrial leader in dental implantology Straumann will further contribute to the dissemination and exploitation strategies of future personalized regenerative medicine treatments in Europe.
|Develop a common clinical protocol for ethical committees and Medicine Agency submission||Documents, reports||2020-02-18 10:42:44|
|Website management : creation and update throughout the project||Websites, patent fillings, videos etc.||2020-02-18 10:42:44|
Take a look to the deliverables list in detail: detailed list of MAXIBONE deliverables.
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The information about "MAXIBONE" are provided by the European Opendata Portal: CORDIS opendata.
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