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IMCUSTOMEYE SIGNED

IMaging-based CUSTOMised EYE diagnostics

Total Cost €

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EC-Contrib. €

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Partnership

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Project "IMCUSTOMEYE" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://www.imcustomeye.eu/
 Total cost 6˙552˙841 €
 EC max contribution 5˙931˙669 € (91%)
 Programme 1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
 Code Call H2020-ICT-2017-1
 Funding Scheme IA
 Starting year 2018
 Duration (year-month-day) from 2018-01-01   to  2021-12-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 1˙457˙423.00
2    INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK PL (WARSZAWA) participant 979˙000.00
3    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) participant 824˙881.00
4    NATIONAL UNIVERSITY OF IRELAND GALWAY IE (Galway) participant 820˙413.00
5    IROC SCIENCE TO INNOVATION AG CH (ZUG) participant 463˙804.00
6    OCULUS OPTIKGERATE GESELLSCHAFT MITBESCHRANKTER HAFTUNG DE (WETZLAR) participant 286˙328.00
7    OPTIMO MEDICAL AG CH (BIEL) participant 280˙612.00
8    INSTITUTO OFTALMOLOGICO FERNANDEZ-VEGA SL ES (OVIEDO ASTURIAS) participant 261˙121.00
9    MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST UK (LONDON) participant 239˙630.00
10    UNIVERSITY COLLEGE LONDON UK (LONDON) participant 160˙918.00
11    2 EYES VISION SL ES (MADRID) participant 157˙535.00

Map

 Project objective

Prevalent eye diseases, such as glaucoma, keratoconus, refractive errors, cataract, myopia and presbyopia, affect millions worldwide, and only in Europe represent over €20 billion annual cost to society. Current screening tools rely on morphological biomarkers based on corneal shape and optics, yet differences in biomechanical properties underlie and precede disease development (i.e. keratoconus, ectasia risk) or affect standard markers (i.e. intraocular pressure in glaucoma). IMCUSTOMEYE will develop new diagnostic paradigms for these vision-threatening conditions, with a direct impact on their treatment. We will deploy new compact, easy-to-use, label-free non-invasive imaging-based instrumentation for direct measurement of corneal biomechanical properties in patients. The technology is based on imaging concepts brought from other disciplines into ophthalmology and, for the first time, applied in patients in vivo. Dynamic corneal imaging based on air-puff stimulated Optical Coherence Tomography corneal deformation and acoustic stimulated phase sensitive and nanosensitive Optical Coherence Tomography corneal vibrography will be coupled to corneal mechanical models to estimate corneal elasticity and viscoelasticity parameters (isolated from other factors). Corneal biomechanical properties will be used as biomarkers for in-depth diagnosis of keratoconus and ectasia risk, and to provide accurate estimates of intraocular pressure in glaucoma diagnosis. Clinical validations in ophthalmology hospitals will demonstrate the diagnostic and treatment predictive potential of the customised optical and biomechanical eye models from patient-specific enabled by the new technology. IMCUSTOMEYE will contribute to more effective, customised treatment of eye diseases and to reinforce industrial leadership in the area of diagnostic imaging in ophthalmology.

 Publications

year authors and title journal last update
List of publications.
2018 Eliasy, A., Chen, K. J., Vinciguerra, R., & Elsheikh, A.
Novel Intraocular Pressure Measurement Algorithm for Patients with Keratoconus
published pages: , ISSN: , DOI:
2020-01-30
2018 Maklad, O., Theofilis, V., & Elsheikh, A.
Fluid Structure Interaction (FSI) Simulation Of the human eye under the air puff tonometry using Computational Fluid Dynamics (CFD)
published pages: , ISSN: , DOI:
2020-01-30
2018 J. Birkenfeld, A. Ramier, B. Tavakol, S. Marcos and S. Yun
Assessment of ocular mechanical resonances using phase-sensitive OCT and frequency-domain air puff stimulation
published pages: , ISSN: , DOI:
2020-01-30
2018 Elsheikh, A., Eliasy, A., Chen, K. J., & Vinciguerra, R.
Obtaining biomechanical properties of corneal tissue in-vivo using a non-contact method
published pages: , ISSN: , DOI:
2020-01-30
2019 Ewa Maczynska, Karol Karnowski, Krzysztof Szulzycki, Monika Malinowska, Hubert Dolezyczek, Artur Cichanski, Maciej Wojtkowski, Bartlomiej Kaluzny, Ireneusz Grulkowski
Assessment of the influence of viscoelasticity of cornea in animal ex vivo model using air-puff optical coherence tomography and corneal hysteresis
published pages: e201800154, ISSN: 1864-063X, DOI: 10.1002/jbio.201800154
Journal of Biophotonics 12/2 2020-01-30
2018 A. Curatolo, J. Birkenfeld, J. A. Germann, A. de Castro, G. Muralidharan, M. Velasco, E. Martínez, and S. Marcos
Customised optical coherence tomography system for corneal deformation imaging on multiple meridians
published pages: , ISSN: , DOI:
2020-01-30
2018 Eliasy, A., Zhou, D., Studer, H., Boote, C., & Elsheikh, A.
Biomechanics of the Eye _ Chapter 6. Material properties of the human cornea: anisotropy
published pages: , ISSN: , DOI:
Material properties of the human cornea: anisotropy 2020-01-30
2018 Eliasy, A., Elsheikh, A., & Chen, K. -J.
Intraocular Pressure Measurement Pre- and Post Refractive Surgery Using GAT and CorVis ST bIOP Algorithm
published pages: , ISSN: , DOI:
2020-01-30
2018 Ryan McAuley, A. Nolan, K. Larin, M. Singh, S. Alexandrov, Martin Leahy
Background Subtraction Vs Highpass filtering in phase sensitive Optica Coherence Tomography
published pages: , ISSN: , DOI:
Bi-annual Biophotonics and Imaging Summer School (BIGSS\'18) 2020-01-30

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The information about "IMCUSTOMEYE" are provided by the European Opendata Portal: CORDIS opendata.

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