NanoTBTech SIGNED
Nanoparticles-based 2D thermal bioimaging technologies
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0NanoTBTech project word cloud
Explore the words cloud of the NanoTBTech project. It provides you a very rough idea of what is the project "NanoTBTech" about.
Project "NanoTBTech" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSIDADE DE AVEIRO
Organization address contact info |
| Coordinator Country | Portugal [PT] |
| Project website | http://www.nanotbtech.eu/ |
| Total cost | 2˙999˙482 € |
| EC max contribution | 2˙999˙482 € (100%) |
| Programme |
1. H2020-EU.1.2.1. (FET Open) |
| Code Call | H2020-FETOPEN-1-2016-2017 |
| Funding Scheme | RIA |
| Starting year | 2018 |
| Duration (year-month-day) | from 2018-09-01 to 2021-08-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSIDADE DE AVEIRO | PT (AVEIRO) | coordinator | 508˙060.00 |
| 2 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS | FR (PARIS) | participant | 467˙025.00 |
| 3 | FUNDACION PARA LA INVESTIGACION BIOMEDICA DEL HOSPITAL UNIVERSITARIO RAMON Y CAJAL | ES (MADRID) | participant | 450˙250.00 |
| 4 | AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS | ES (MADRID) | participant | 354˙432.00 |
| 5 | INSTYTUT NISKICH TEMPERATUR I BADAN STRUKTURALNYCH IM. WLODZIMIERZA TRZEBIATOWSKIEGO POLSKIEJ AKADEMII NAUK | PL (WROCLAW) | participant | 277˙375.00 |
| 6 | INSTITUT ZA NUKLEARNE NAUKE VINCA | RS (VINCA BEOGRAD) | participant | 258˙750.00 |
| 7 | BIOSPACE LAB | FR (NESLES-LA-VALLEE) | participant | 243˙737.00 |
| 8 | UNIVERSITEIT UTRECHT | NL (UTRECHT) | participant | 234˙375.00 |
| 9 | NANOIMMUNOTECH SL | ES (VIGO PONTEVEDRA) | participant | 205˙477.00 |
Map
Project objective
Temperature measurements are crucial in countless technological developments, accounting for 80% of the sensor market throughout the world. The pitfalls of temperature readouts at the biomedical battleground are mostly represented by the currently achievable spatial resolution. To address key issues, such as intracellular temperature fluctuations and in vivo thermal transients, a technique able to go clearly below 1 μm is highly and urgently needed, as the traditional contact-based sensors and near infrared thermometers are not suitable for measurements at that tight spatial range. To overcome these limitations requires a non-contact thermometry approach granted with sub-micrometer resolution, also providing real-time high relative thermal sensitivity values.
The goal of NanoTBTech is to develop a 2-D thermal bioimaging technology featuring sub-microscale resolution, based on nanothermometers and heater-thermometer nanostructures. We will design, synthetize, and bio-functionalize nontoxic luminescent nanostructures, operating essentially beyond 1000 nm, for in vivo nanothermometry and nanoheating. Furthermore, to monitor the temperature-dependent nanostructures’ luminescence we will develop a novel imaging system. The effective delivery of that major advance in 2-D thermal bioimaging will be implemented through two impactful biomedical showcases: highly spatially-modulated intracellular magnetic/optical hyperthermia and in vivo detection and tracking of cancer.
In the long-term, we foresee our technology having a broad impact on non-invasive clinical imaging and theranostics. For instance, the accurate measurement of temperature gradients´ sources will be an invaluable tool for real-time control of thermal therapies, thus making them harmless for the patient. Multiple conceptual breakthroughs can be further envisaged from the proposed 2D-thermal imaging system, credibly spreading its impact towards non-biomedical technological areas.
Deliverables
| First calibration datasheets for in vivo imaging | Documents, reports | 2019-11-14 10:13:19 |
| First report of in vivo detection of tumours | Documents, reports | 2019-11-14 10:13:15 |
| Leaflet | Websites, patent fillings, videos etc. | 2019-11-14 10:13:26 |
| Web site and logo | Websites, patent fillings, videos etc. | 2019-11-14 10:13:21 |
| First round of nanoheaters and nanoplatforms | Documents, reports | 2019-11-14 10:13:19 |
| Instruction manuals: first edition | Documents, reports | 2019-11-14 10:13:05 |
| Powder-to-colloidal nanoparticles protocol | Documents, reports | 2019-11-14 10:13:09 |
| Core-shell nanoparticles | Documents, reports | 2019-11-14 10:13:05 |
| Report on the NPs functionalization | Documents, reports | 2019-11-14 10:13:06 |
| Data Management Plan | Open Research Data Pilot | 2019-11-14 10:13:22 |
| Basic model of energy transfer in nanocrystals | Documents, reports | 2019-11-14 10:13:05 |
| Dissemination and Exploitation Plan | Documents, reports | 2019-11-14 10:13:24 |
| Cell temperature gradients report | Documents, reports | 2019-11-14 10:13:20 |
| First generation of nanoparticles | Documents, reports | 2019-11-14 10:13:05 |
Take a look to the deliverables list in detail: detailed list of NanoTBTech deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Sekulić, Milica; Ristić, Zoran; Milićević, Bojana; Antić, Željka; ÄorÄ‘ević, Vesna; Dramićanin, Miroslav Li1.8Na0.2TiO3:Mn4+: the highly sensitive probe for the low-temperature lifetime-based luminescence thermometry published pages: 342-346, ISSN: 0030-4018, DOI: 10.5281/zenodo.3407311 |
Optics Communications 3 | 2019-10-08 |
| 2018 |
Susana Carregal-Romero, Sandra Plaza-GarcÃa, Rafael Piñol, José Murillo, Jesús Ruiz-Cabello, Daniel Padro, Angel Millán, Pedro Ramos-Cabrer MRI Study of the Influence of Surface Coating Aging on the In Vivo Biodistribution of Iron Oxide Nanoparticles published pages: 127, ISSN: 2079-6374, DOI: 10.3390/bios8040127 |
Biosensors 8/4 | 2019-10-08 |
| 2019 |
Carlos D. S. Brites, Sangeetha Balabhadra, LuÃs D. Carlos Lanthanide-Based Thermometers: At the Cutting-Edge of Luminescence Thermometry published pages: 1801239, ISSN: 2195-1071, DOI: 10.1002/adom.201801239 |
Advanced Optical Materials | 2019-05-18 |
| 2018 |
Blanca del Rosal, Diego Ruiz, Irene Chaves-Coira, Beatriz H. Juárez, Luis Monge, Guosong Hong, Nuria Fernández, Daniel Jaque In Vivo Contactless Brain Nanothermometry published pages: 1806088, ISSN: 1616-301X, DOI: 10.1002/adfm.201806088 |
Advanced Functional Materials 28/52 | 2019-05-18 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "NANOTBTECH" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "NANOTBTECH" are provided by the European Opendata Portal: CORDIS opendata.