Explore the words cloud of the Fields4CAT project. It provides you a very rough idea of what is the project "Fields4CAT" about.
The following table provides information about the project.
KING'S COLLEGE LONDON
|Coordinator Country||United Kingdom [UK]|
|Total cost||1˙998˙700 €|
|EC max contribution||1˙998˙700 € (100%)|
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
|Duration (year-month-day)||from 2019-03-01 to 2024-02-29|
Take a look of project's partnership.
|1||KING'S COLLEGE LONDON||UK (LONDON)||coordinator||1˙998˙700.00|
|2||UNIVERSITAT DE BARCELONA||ES (BARCELONA)||participant||0.00|
Fields4CAT aims to identify the nature and directionality of the driving forces in a redox enzyme that govern the catalytic chemical process. Industrial bio-manufacturing is one of the pillars of today’s world economy making its way to a sustainable development. Redox enzymes catalyze the most demanding chemical reactions under mild conditions, such as the oxy-functionalization of non-activated hydrocarbons, which usually requires harsh reaction conditions. Enzyme Biotechnology has greatly progressed thanks to rational mutagenesis schemes that draw upon the static X-ray structural information. The high complexity of enzymatic catalysis has, however, hampered its development because a single point mutation near the active site can affect several relevant parameters at the same time, obscuring the interpretation and constraining the rational design of technological biocatalysts. Fields4CAT proposes dissecting the relevant forces exerted over an individual catalytic active site in its wild-type state, and then using the resulting forces map to design enzyme/metal platforms with enhanced capabilities. To this aim, it develops in 3 blocks organized in a step-wise fashion: (i) block 1 sets up a electrochemical multi-stimuli single-protein toolbox (Ec-SPT) with capabilities to trap individual proteins in a nanoscale tunnelling junction and subject them to a variety of force stimuli, i.e. mechanical, electrostatic and magnetic. (ii) Block 2 designs the chemical electrical plugs that will specifically connect the enzyme to the junction electrodes with precise controlled orientation. (iii) Block 3 characterizes the single-protein electrical signatures of the enzyme activity and quantifies the catalytic effect of the different force stimuli along the vertical junction axis. Fields4CAT will identify new guidelines to bioengineer a redox enzyme/metal platform with tuned catalytic activity, bringing about new breakthroughs in the future of Bio-Catalysis.
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "FIELDS4CAT" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (email@example.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "FIELDS4CAT" are provided by the European Opendata Portal: CORDIS opendata.
The Enemy of the Good: Towards a Theory of Moral ProgressRead More
The Power of Randomness and Continuity in Submodular OptimizationRead More
Streamlined carbon dioxide conversion in ionic liquids – a platform strategy for modern carbonylation chemistryRead More