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MechanoTubes SIGNED

Supramolecular machineries with life-like mechanical functions

Total Cost €

0

EC-Contrib. €

0

Partnership

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 MechanoTubes project word cloud

Explore the words cloud of the MechanoTubes project. It provides you a very rough idea of what is the project "MechanoTubes" about.

yield    machineries    grow    splitting    models    microtubules    measurable    engineer    inspiration    continuous    unaccounted    ultimately    disassembly    assemblies    generating    switches    polymer    mechanical    principles    nanoscale    strategies    mechanically    synthetic    directional    manipulate    solution    illumination    nanotechnology    synthesize    pioneering    motors    nanoparticles    molecular    water    length    energy    rudimentary    brownian    forces    shape    droplets    macroscopic    bridging    manipulating    storm    microscopic    harness    crystals    scales    disassemble    dynamic    shifting    cells    tubes    networks    stops    formations    action    stiff    light    adaptive    draw    input    sense    core    incorporate    stroke    generate    motion    transduction    actively    strain    encapsulate    operation    harvest    soon    vesicles    chemo    supramolecular    wholly    dispersed    foundations    cytoskeleton    purposeful    power    operates    molecules    directionality    unprecedented    gap    lays    artificial    photo    nano    individual    perform   

Project "MechanoTubes" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2024-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 2˙000˙000.00

Map

 Project objective

Artificial molecular motors and switches have the potential to become a core part of nanotechnology. However, a wide gap in length scales still remains unaccounted for, between the operation of these molecules in solution, where their individual mechanical action is randomly dispersed in the Brownian storm, and on the other hand their action at the macroscopic level, e.g. in polymer networks and crystals.

This proposal is about bridging this gap, by developing chemo-mechanical transduction strategies that will allow dynamic molecules to perform a range of unprecedented tasks, e.g. by generating strong directional forces at the nanoscale, and through shape-shifting microscopic formations.

This project aims to harness the mechanically-purposeful motion of dynamic molecules as to generate measurable forces from the nanoscale, and ultimately establish operational principles for chemo-mechanical transduction in supramolecular systems.

In my wholly synthetic approach, I draw inspiration from the operational principles of microtubules. I will incorporate molecular photo-switches into supramolecular tubes, and enable the controlled growth and disassembly of the tubes by using light as the energy input. Thus, I will: (i) Synthesize stiff supramolecular tubes that grow actively under continuous illumination, and disassemble with a power stroke as soon as illumination stops; (ii) Measure, and harvest the forces generated by the tubes to manipulate individual nanoparticles with a sense of directionality; and (iii) Encapsulate the tubes into water droplets and vesicles, to yield shape-shifting, and eventually rudimentary splitting models for cells.

This project reaches beyond the state of the art in adaptive molecular nano-systems, by pioneering strategies to engineer and harness strain in supramolecular assemblies. It thus lays the foundations for machineries that are capable of manipulating matter at length scales that are also those at which the cytoskeleton operates.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MECHANOTUBES" project.

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The information about "MECHANOTUBES" are provided by the European Opendata Portal: CORDIS opendata.

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