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MechanoTubes SIGNED

Supramolecular machineries with life-like mechanical functions

Total Cost €

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EC-Contrib. €

0

Partnership

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 MechanoTubes project word cloud

Explore the words cloud of the MechanoTubes project. It provides you a very rough idea of what is the project "MechanoTubes" about.

scales    ultimately    networks    shape    harness    engineer    switches    illumination    chemo    models    stroke    brownian    directionality    solution    directional    operates    perform    foundations    light    yield    generate    stops    rudimentary    assemblies    incorporate    power    photo    core    grow    nano    shifting    lays    operation    dynamic    nanotechnology    microtubules    nanoscale    purposeful    energy    unaccounted    manipulate    synthesize    microscopic    inspiration    strategies    actively    artificial    mechanical    motors    molecules    crystals    measurable    water    action    machineries    individual    cytoskeleton    input    cells    bridging    encapsulate    storm    macroscopic    adaptive    unprecedented    strain    supramolecular    wholly    motion    gap    molecular    polymer    generating    disassembly    disassemble    sense    length    forces    manipulating    vesicles    draw    splitting    harvest    formations    dispersed    stiff    principles    pioneering    tubes    droplets    nanoparticles    transduction    mechanically    continuous    synthetic    soon   

Project "MechanoTubes" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2024-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 2˙000˙000.00

Map

Leaflet | Map data © OpenStreetMap contributors, CC-BY-SA, Imagery © Mapbox

 Project objective

Artificial molecular motors and switches have the potential to become a core part of nanotechnology. However, a wide gap in length scales still remains unaccounted for, between the operation of these molecules in solution, where their individual mechanical action is randomly dispersed in the Brownian storm, and on the other hand their action at the macroscopic level, e.g. in polymer networks and crystals.

This proposal is about bridging this gap, by developing chemo-mechanical transduction strategies that will allow dynamic molecules to perform a range of unprecedented tasks, e.g. by generating strong directional forces at the nanoscale, and through shape-shifting microscopic formations.

This project aims to harness the mechanically-purposeful motion of dynamic molecules as to generate measurable forces from the nanoscale, and ultimately establish operational principles for chemo-mechanical transduction in supramolecular systems.

In my wholly synthetic approach, I draw inspiration from the operational principles of microtubules. I will incorporate molecular photo-switches into supramolecular tubes, and enable the controlled growth and disassembly of the tubes by using light as the energy input. Thus, I will: (i) Synthesize stiff supramolecular tubes that grow actively under continuous illumination, and disassemble with a power stroke as soon as illumination stops; (ii) Measure, and harvest the forces generated by the tubes to manipulate individual nanoparticles with a sense of directionality; and (iii) Encapsulate the tubes into water droplets and vesicles, to yield shape-shifting, and eventually rudimentary splitting models for cells.

This project reaches beyond the state of the art in adaptive molecular nano-systems, by pioneering strategies to engineer and harness strain in supramolecular assemblies. It thus lays the foundations for machineries that are capable of manipulating matter at length scales that are also those at which the cytoskeleton operates.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MECHANOTUBES" project.

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Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "MECHANOTUBES" are provided by the European Opendata Portal: CORDIS opendata.

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