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MechanoTubes SIGNED

Supramolecular machineries with life-like mechanical functions

Total Cost €

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EC-Contrib. €

0

Partnership

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 MechanoTubes project word cloud

Explore the words cloud of the MechanoTubes project. It provides you a very rough idea of what is the project "MechanoTubes" about.

operation    unprecedented    scales    generate    measurable    formations    dynamic    actively    length    ultimately    adaptive    bridging    incorporate    crystals    operates    forces    action    manipulate    manipulating    encapsulate    microscopic    water    harness    splitting    cells    assemblies    droplets    molecules    draw    energy    synthetic    shape    supramolecular    harvest    macroscopic    disassembly    photo    microtubules    shifting    networks    light    sense    disassemble    motors    lays    chemo    brownian    molecular    nanoparticles    strategies    input    switches    nano    synthesize    dispersed    strain    mechanically    vesicles    unaccounted    continuous    polymer    generating    mechanical    stops    core    nanoscale    engineer    directionality    purposeful    directional    cytoskeleton    perform    stroke    yield    principles    power    artificial    grow    tubes    transduction    illumination    soon    wholly    machineries    gap    nanotechnology    models    solution    inspiration    rudimentary    pioneering    foundations    individual    storm    stiff    motion   

Project "MechanoTubes" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2024-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 2˙000˙000.00

Map

 Project objective

Artificial molecular motors and switches have the potential to become a core part of nanotechnology. However, a wide gap in length scales still remains unaccounted for, between the operation of these molecules in solution, where their individual mechanical action is randomly dispersed in the Brownian storm, and on the other hand their action at the macroscopic level, e.g. in polymer networks and crystals.

This proposal is about bridging this gap, by developing chemo-mechanical transduction strategies that will allow dynamic molecules to perform a range of unprecedented tasks, e.g. by generating strong directional forces at the nanoscale, and through shape-shifting microscopic formations.

This project aims to harness the mechanically-purposeful motion of dynamic molecules as to generate measurable forces from the nanoscale, and ultimately establish operational principles for chemo-mechanical transduction in supramolecular systems.

In my wholly synthetic approach, I draw inspiration from the operational principles of microtubules. I will incorporate molecular photo-switches into supramolecular tubes, and enable the controlled growth and disassembly of the tubes by using light as the energy input. Thus, I will: (i) Synthesize stiff supramolecular tubes that grow actively under continuous illumination, and disassemble with a power stroke as soon as illumination stops; (ii) Measure, and harvest the forces generated by the tubes to manipulate individual nanoparticles with a sense of directionality; and (iii) Encapsulate the tubes into water droplets and vesicles, to yield shape-shifting, and eventually rudimentary splitting models for cells.

This project reaches beyond the state of the art in adaptive molecular nano-systems, by pioneering strategies to engineer and harness strain in supramolecular assemblies. It thus lays the foundations for machineries that are capable of manipulating matter at length scales that are also those at which the cytoskeleton operates.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MECHANOTUBES" project.

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The information about "MECHANOTUBES" are provided by the European Opendata Portal: CORDIS opendata.

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