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MechanoTubes SIGNED

Supramolecular machineries with life-like mechanical functions

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 MechanoTubes project word cloud

Explore the words cloud of the MechanoTubes project. It provides you a very rough idea of what is the project "MechanoTubes" about.

unaccounted    incorporate    networks    perform    ultimately    solution    grow    generate    measurable    motors    harvest    dispersed    harness    core    illumination    tubes    microscopic    machineries    individual    yield    shape    foundations    macroscopic    nanoscale    sense    chemo    manipulating    nanotechnology    strategies    rudimentary    artificial    polymer    switches    photo    models    input    light    brownian    disassemble    microtubules    unprecedented    encapsulate    inspiration    operation    nanoparticles    generating    storm    molecular    disassembly    principles    energy    manipulate    droplets    stroke    cytoskeleton    stiff    draw    water    shifting    supramolecular    motion    continuous    lays    pioneering    adaptive    bridging    stops    directionality    power    purposeful    length    strain    scales    nano    synthesize    cells    mechanically    mechanical    dynamic    operates    engineer    directional    assemblies    gap    wholly    forces    actively    transduction    crystals    synthetic    vesicles    splitting    soon    action    molecules    formations   

Project "MechanoTubes" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2024-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 2˙000˙000.00

Map

 Project objective

Artificial molecular motors and switches have the potential to become a core part of nanotechnology. However, a wide gap in length scales still remains unaccounted for, between the operation of these molecules in solution, where their individual mechanical action is randomly dispersed in the Brownian storm, and on the other hand their action at the macroscopic level, e.g. in polymer networks and crystals.

This proposal is about bridging this gap, by developing chemo-mechanical transduction strategies that will allow dynamic molecules to perform a range of unprecedented tasks, e.g. by generating strong directional forces at the nanoscale, and through shape-shifting microscopic formations.

This project aims to harness the mechanically-purposeful motion of dynamic molecules as to generate measurable forces from the nanoscale, and ultimately establish operational principles for chemo-mechanical transduction in supramolecular systems.

In my wholly synthetic approach, I draw inspiration from the operational principles of microtubules. I will incorporate molecular photo-switches into supramolecular tubes, and enable the controlled growth and disassembly of the tubes by using light as the energy input. Thus, I will: (i) Synthesize stiff supramolecular tubes that grow actively under continuous illumination, and disassemble with a power stroke as soon as illumination stops; (ii) Measure, and harvest the forces generated by the tubes to manipulate individual nanoparticles with a sense of directionality; and (iii) Encapsulate the tubes into water droplets and vesicles, to yield shape-shifting, and eventually rudimentary splitting models for cells.

This project reaches beyond the state of the art in adaptive molecular nano-systems, by pioneering strategies to engineer and harness strain in supramolecular assemblies. It thus lays the foundations for machineries that are capable of manipulating matter at length scales that are also those at which the cytoskeleton operates.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MECHANOTUBES" project.

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The information about "MECHANOTUBES" are provided by the European Opendata Portal: CORDIS opendata.

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