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MechanoTubes SIGNED

Supramolecular machineries with life-like mechanical functions

Total Cost €

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EC-Contrib. €

0

Partnership

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 MechanoTubes project word cloud

Explore the words cloud of the MechanoTubes project. It provides you a very rough idea of what is the project "MechanoTubes" about.

generate    ultimately    assemblies    incorporate    nanotechnology    measurable    motion    principles    input    energy    unaccounted    polymer    dispersed    stops    lays    photo    directionality    microscopic    cells    scales    disassembly    soon    light    vesicles    storm    rudimentary    generating    chemo    water    splitting    adaptive    motors    supramolecular    microtubules    solution    disassemble    crystals    mechanical    foundations    nanoparticles    manipulate    illumination    unprecedented    grow    shifting    dynamic    length    yield    encapsulate    actively    manipulating    harness    artificial    droplets    tubes    stroke    switches    brownian    formations    core    harvest    sense    operation    bridging    wholly    draw    strain    mechanically    action    gap    engineer    operates    cytoskeleton    forces    machineries    models    synthetic    molecular    nanoscale    purposeful    directional    stiff    strategies    transduction    continuous    macroscopic    networks    power    molecules    synthesize    pioneering    individual    shape    perform    nano    inspiration   

Project "MechanoTubes" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITEIT TWENTE 

Organization address
address: DRIENERLOLAAN 5
city: ENSCHEDE
postcode: 7522 NB
website: www.utwente.nl

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Netherlands [NL]
 Total cost 2˙000˙000 €
 EC max contribution 2˙000˙000 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2018-COG
 Funding Scheme ERC-COG
 Starting year 2019
 Duration (year-month-day) from 2019-03-01   to  2024-02-29

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITEIT TWENTE NL (ENSCHEDE) coordinator 2˙000˙000.00

Map

 Project objective

Artificial molecular motors and switches have the potential to become a core part of nanotechnology. However, a wide gap in length scales still remains unaccounted for, between the operation of these molecules in solution, where their individual mechanical action is randomly dispersed in the Brownian storm, and on the other hand their action at the macroscopic level, e.g. in polymer networks and crystals.

This proposal is about bridging this gap, by developing chemo-mechanical transduction strategies that will allow dynamic molecules to perform a range of unprecedented tasks, e.g. by generating strong directional forces at the nanoscale, and through shape-shifting microscopic formations.

This project aims to harness the mechanically-purposeful motion of dynamic molecules as to generate measurable forces from the nanoscale, and ultimately establish operational principles for chemo-mechanical transduction in supramolecular systems.

In my wholly synthetic approach, I draw inspiration from the operational principles of microtubules. I will incorporate molecular photo-switches into supramolecular tubes, and enable the controlled growth and disassembly of the tubes by using light as the energy input. Thus, I will: (i) Synthesize stiff supramolecular tubes that grow actively under continuous illumination, and disassemble with a power stroke as soon as illumination stops; (ii) Measure, and harvest the forces generated by the tubes to manipulate individual nanoparticles with a sense of directionality; and (iii) Encapsulate the tubes into water droplets and vesicles, to yield shape-shifting, and eventually rudimentary splitting models for cells.

This project reaches beyond the state of the art in adaptive molecular nano-systems, by pioneering strategies to engineer and harness strain in supramolecular assemblies. It thus lays the foundations for machineries that are capable of manipulating matter at length scales that are also those at which the cytoskeleton operates.

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The information about "MECHANOTUBES" are provided by the European Opendata Portal: CORDIS opendata.

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