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Improvement of food safety applied biosensors by protein engineering

Total Cost €


EC-Contrib. €






 BIOIMPROVE project word cloud

Explore the words cloud of the BIOIMPROVE project. It provides you a very rough idea of what is the project "BIOIMPROVE" about.

concentration    biosensor    hygienic    performed    molecules    biogune    computational    mg    she    mutational    structural    guaranteeing    bioimprove    determination    centre    freshness    complementary    lt    spanish    innovative    gaining    hazardous    microbiosensores    opportunity    environment    enzyme    scombroid    materials    poisoning    secondment    safety    academy    pursuing    quantification    reputation    device    detecting    industry    quality    strategy    food    protein    detect    screening    conduct    stages    ultimately    maximize    biosensing    generation    tandem    competences    biosensors    consumers    career    hotspots    careful    dr    either    successful    monitoring    gangoiti    content    multidisciplinary    sensitivity    sme    allergy    rational    thanks    libraries    fish    expertise    chain    raw    portable    sensitive    powerful    cic    lower    biolan    engineering    paramount    susceptible    health    tools    histamine    carry    contamination    semi    prevent   

Project "BIOIMPROVE" data sheet

The following table provides information about the project.


Organization address
postcode: 48170
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 172˙932 €
 EC max contribution 172˙932 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-SE
 Starting year 2019
 Duration (year-month-day) from 2019-05-01   to  2021-08-18


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    BIOLAN MICROBIOSENSORES SL ES (ZAMUDIO) coordinator 172˙932.00


 Project objective

Determination of the histamine content is of paramount importance for the food industry as a parameter of the hygienic quality and freshness of food, as well as to prevent scombroid fish poisoning, an allergy-like food poisoning. At present, more sensitive and user-friendly methods for histamine monitoring are needed to early detect products and raw materials susceptible of becoming hazardous for consumers. BIOIMPROVE aims to develop an improved and highly sensitive portable biosensing device for the quantification of histamine in the lower concentration range (<5 mg/l). To reach this objective, an innovative and powerful semi-rational protein engineering strategy will be used to maximize the sensitivity of the currently available histamine enzyme-based biosensor. Rather than addressing this goal by the generation and screening of large libraries, a careful selection of the most promising mutational hotspots will be performed using the structural available information in tandem with advanced computational modelling tools. Dr. Gangoiti will carry out BIOIMPROVE project at BIOLAN Microbiosensores, a Spanish SME focused on the development of biosensors capable of detecting health and food-related molecules. To support her research, she will conduct a secondment at CIC bioGUNE, a research centre that has a strong reputation in protein computational design. Thanks to this multidisciplinary research environment, Dr. Gangoiti will have the opportunity of gaining not only a high level of complementary expertise in areas of key importance in the enzyme technology field, but also the competences required for pursuing a successful research career either in industry or academy. Most importantly, the implementation of BIOIMPROVE project is expected to ensure histamine contamination to be identified at all stages of the food chain, ultimately guaranteeing food safety for European consumers.

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The information about "BIOIMPROVE" are provided by the European Opendata Portal: CORDIS opendata.

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lastchecktime (2020-12-04 13:36:07) correctly updated