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SCHENGEN-ROOT SIGNED

'Filling the gaps' in the Schengen pathway for plant root Casparian strip integrity

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 SCHENGEN-ROOT project word cloud

Explore the words cloud of the SCHENGEN-ROOT project. It provides you a very rough idea of what is the project "SCHENGEN-ROOT" about.

domain    broad    receptor    basis    water    understand    clarify    characterise    elucidating    plants    appears    forge    downstream    coat    secondly    sub    functions    intend    cascades    aligned    elusive    linear    embryonic    diffusion    diverse    potentially    additional    starts    specificity    root    unknown    cuticle    govern    regulated    safeguard    ligand    activated    mechanistic    regulate    give    sgn    homeostasis    barrier    continuous    co    model    initiated    central    seal    off    ensures    modules    strip    establishes    organs    membrane    first    fusion    lignification    integrity    fuse    identification    function    tissue    thirdly    transducers    details    mechanism    mapk    molecular    barriers    perceives    monitor    mapks    share    casparian    receptors    pollen    sgn3    signalling    localisation    branched    tissues    missing    inducible    microdomains    engineering    gaps    cifs    uncover    perfect    insights    nutrient    appear    cs    resolve    sophisticated    biological   

Project "SCHENGEN-ROOT" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITE DE LAUSANNE 

Organization address
address: Quartier Unil-Centre Bâtiment Unicentre
city: LAUSANNE
postcode: 1015
website: www.unil.ch

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Switzerland [CH]
 Total cost 203˙149 €
 EC max contribution 203˙149 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2020
 Duration (year-month-day) from 2020-09-01   to  2022-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITE DE LAUSANNE CH (LAUSANNE) coordinator 203˙149.00

Map

 Project objective

Plants have developed sophisticated barriers in various tissues and organs to safeguard integrity. To monitor barrier integrity, plants appear to have evolved similar systems that share signalling modules. The receptor/ligand signalling pathway initiated by SGN3/CIFs establishes the integrity of the Casparian strip (CS), a root diffusion barrier that is essential for controlling nutrient and water homeostasis. The CS starts off as aligned microdomains that eventually fuse to forge a continuous barrier. The SGN pathway is crucial to “find and seal gaps” between the microdomains. However, the mechanism that ensures perfect domain fusion is not well understood.

Here, I aim to uncover missing mechanistic details and characterise central unknown elements in a proposed, branched SGN pathway. I intend to identify potential SGN3 co-receptors and additional membrane transducers, and to investigate the elusive role of MAPKs during CS formation. The findings will be crucial to resolve pathway features that the current linear model cannot explain. First, identifying co-receptors is necessary to understand how SGN3 is activated. SGN3 also appears to be involved in embryonic cuticle and pollen coat formation. Therefore, co-receptor identification would clarify whether SGN3 perceives the same or different ligand to govern distinct barrier formation processes. Secondly, identifying additional transducers will provide a molecular basis for understanding two potentially distinct lignification processes regulated by SGN3. This will provide broad insights into how receptors regulate specific sub-functions. Thirdly, MAPK cascades are activated downstream of many receptor/ligand pathways. Elucidating their function in the SGN pathway will give insights into diverse biological processes. Overall, this project will provide a key model to study specificity and localisation of signalling modules, leading towards tissue-specific and inducible barrier engineering in plants.

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The information about "SCHENGEN-ROOT" are provided by the European Opendata Portal: CORDIS opendata.

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