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Clock-mediated modulation of growth-defense trade-offs and its potential as a biotechnological tool

Total Cost €


EC-Contrib. €






 CHRONOTRADE project word cloud

Explore the words cloud of the CHRONOTRADE project. It provides you a very rough idea of what is the project "CHRONOTRADE" about.

gi    changing    uncouple    mechanism    pivotal    environment    subjected    position    regulators    biological    agriculture    endogenous    expertise    independent    summary    edgetic    agronomical    view    functions    networks    manipulation    tracking    cellular    gigantea    supports    biology    align    regulatory    translate    model    career    generate    organisms    circadian    strategy    complement    solid    cultivated    species    molecular    clocks    timekeepers    outstanding    trained    mechanisms    orientation    traits    basic    connections    hub    gene    undoubtedly    time    capacities    noteworthy    point    fellowship    balance    defense    influence    boost    transferred    pervasive    render    physiology    extensive    innovative    gained    biotechnological    crop    agricultural    plants    clock    sustainable    professional    output    training    consequently    components    regulation    framework    tackle    influences    skills    interface    researcher    physiological    mere    er    alleles    conserved    protein    variants    academic    tomato    plant    arabidopsis    desirable    modulates   

Project "CHRONOTRADE" data sheet

The following table provides information about the project.


Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 172˙932 €
 EC max contribution 172˙932 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2020
 Duration (year-month-day) from 2020-04-01   to  2022-03-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 


 Project objective

Circadian clocks are conserved time-tracking mechanisms that allow organisms to align endogenous physiological processes with the changing environment. Growing evidence supports a role for these biological clocks, not only as mere timekeepers, but as pivotal regulators of extensive cellular networks. In plants, the influence of the clock on development and physiology is pervasive and many traits of agronomical value are subjected to circadian regulation. Noteworthy, clock gene alleles have been traditionally selected because of their desirable influences on key agricultural traits. An outstanding clock protein that functions at the interface between the clock and its output is GIGANTEA (GI). We propose to investigate this regulatory hub protein, and characterize the molecular mechanism by which it modulates the balance between growth and defense. Knowledge gained from the model plant Arabidopsis will be transferred to a crop species (tomato) in order to establish a framework for targeted biotechnological manipulation. Consequently, an innovative strategy based on edgetic alleles will be deployed to generate new GI alleles that uncouple growth from defense, a key feature for cultivated species. From a training point of view, this fellowship will build on the Experienced Researcher’s (ER) solid expertise on molecular biology and complement it with the skills required to translate basic research to tackle specific agronomical issues. This will undoubtedly boost her opportunities to reach an independent research position with biotechnological orientation. In summary, this proposal aims to (i) advance our understanding on the connections between the clock and its output in model and crop species, (ii) generate novel variants of circadian-clock components as a biotechnological strategy for sustainable agriculture, and (iii) render a well-trained academic researcher with the capacities needed to develop a professional career within biotechnological research.

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The information about "CHRONOTRADE" are provided by the European Opendata Portal: CORDIS opendata.

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