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CHRONOTRADE SIGNED

Clock-mediated modulation of growth-defense trade-offs and its potential as a biotechnological tool

Total Cost €

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EC-Contrib. €

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Partnership

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 CHRONOTRADE project word cloud

Explore the words cloud of the CHRONOTRADE project. It provides you a very rough idea of what is the project "CHRONOTRADE" about.

generate    biological    position    protein    pivotal    molecular    tackle    solid    tracking    clocks    trained    modulates    career    subjected    er    mere    fellowship    endogenous    mechanisms    point    independent    render    traits    basic    consequently    biology    arabidopsis    pervasive    functions    gi    manipulation    balance    cellular    desirable    environment    tomato    influence    mechanism    connections    plant    crop    summary    agriculture    timekeepers    academic    innovative    cultivated    changing    physiological    agronomical    align    clock    edgetic    alleles    undoubtedly    time    conserved    variants    view    sustainable    model    noteworthy    training    outstanding    researcher    gained    framework    plants    supports    species    agricultural    regulatory    capacities    boost    professional    strategy    defense    complement    uncouple    interface    gigantea    networks    regulators    gene    skills    regulation    organisms    physiology    hub    biotechnological    extensive    influences    expertise    orientation    components    transferred    translate    circadian    output   

Project "CHRONOTRADE" data sheet

The following table provides information about the project.

Coordinator
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS 

Organization address
address: CALLE SERRANO 117
city: MADRID
postcode: 28006
website: http://www.csic.es

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Total cost 172˙932 €
 EC max contribution 172˙932 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2019
 Funding Scheme MSCA-IF-EF-RI
 Starting year 2020
 Duration (year-month-day) from 2020-04-01   to  2022-03-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS ES (MADRID) coordinator 172˙932.00

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 Project objective

Circadian clocks are conserved time-tracking mechanisms that allow organisms to align endogenous physiological processes with the changing environment. Growing evidence supports a role for these biological clocks, not only as mere timekeepers, but as pivotal regulators of extensive cellular networks. In plants, the influence of the clock on development and physiology is pervasive and many traits of agronomical value are subjected to circadian regulation. Noteworthy, clock gene alleles have been traditionally selected because of their desirable influences on key agricultural traits. An outstanding clock protein that functions at the interface between the clock and its output is GIGANTEA (GI). We propose to investigate this regulatory hub protein, and characterize the molecular mechanism by which it modulates the balance between growth and defense. Knowledge gained from the model plant Arabidopsis will be transferred to a crop species (tomato) in order to establish a framework for targeted biotechnological manipulation. Consequently, an innovative strategy based on edgetic alleles will be deployed to generate new GI alleles that uncouple growth from defense, a key feature for cultivated species. From a training point of view, this fellowship will build on the Experienced Researcher’s (ER) solid expertise on molecular biology and complement it with the skills required to translate basic research to tackle specific agronomical issues. This will undoubtedly boost her opportunities to reach an independent research position with biotechnological orientation. In summary, this proposal aims to (i) advance our understanding on the connections between the clock and its output in model and crop species, (ii) generate novel variants of circadian-clock components as a biotechnological strategy for sustainable agriculture, and (iii) render a well-trained academic researcher with the capacities needed to develop a professional career within biotechnological research.

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