ADITEC

Advanced Immunization Technologies

 Coordinatore SCLAVO VACCINES ASSOCIATION 

 Organization address address: PIAZZA LA LIZZA 7
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: Rino
Cognome: Rappuoli
Email: send email
Telefono: +39 0577 206819

 Nazionalità Coordinatore Italy [IT]
 Totale costo 40˙876˙617 €
 EC contributo 29˙980˙670 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2011-single-stage
 Funding Scheme CP-IP
 Anno di inizio 2011
 Periodo (anno-mese-giorno) 2011-10-01   -   2016-09-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    SCLAVO VACCINES ASSOCIATION

 Organization address address: PIAZZA LA LIZZA 7
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: Rino
Cognome: Rappuoli
Email: send email
Telefono: +39 0577 206819

IT (SIENA) coordinator 5˙052˙094.10
2    UNIVERSITY OF SURREY

 Organization address address: Stag Hill
city: GUILDFORD
postcode: GU2 7XH

contact info
Titolo: Ms.
Nome: Maria
Cognome: Sega-Buhalis
Email: send email
Telefono: +44 1483 683498
Fax: +44 1483 683791

UK (GUILDFORD) participant 1˙331˙163.00
3    UNIVERSITA' DEGLI STUDI DI SIENA

 Organization address address: VIA BANCHI DI SOTTO 55
city: SIENA
postcode: 53100

contact info
Titolo: Prof.
Nome: Angelo
Cognome: Riccaboni
Email: send email
Telefono: +39 0577 232206

IT (SIENA) participant 1˙314˙800.00
4    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

 Organization address address: University Offices, Wellington Square
city: OXFORD
postcode: OX1 2JD

contact info
Titolo: Dr.
Nome: Stephen
Cognome: Conway
Email: send email
Telefono: +44 1865 289811
Fax: +44 1865 222737

UK (OXFORD) participant 1˙225˙900.00
5    STATENS SERUM INSTITUT

 Organization address address: ARTILLERIVEJ 5
city: KOBENHAVN S
postcode: 2300

contact info
Titolo: Mr.
Nome: Ole Allin
Cognome: Jensen
Email: send email
Telefono: 4532683462
Fax: 4532683035

DK (KOBENHAVN S) participant 1˙098˙248.40
6    MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V.

 Organization address address: Hofgartenstrasse 8
city: MUENCHEN
postcode: 80539

contact info
Titolo: Dr.
Nome: Robert
Cognome: Golinski
Email: send email
Telefono: +49 30 28460 555
Fax: +49 30 28460 501

DE (MUENCHEN) participant 1˙026˙250.00
7    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

 Organization address address: RUE LEBLANC 25
city: PARIS 15
postcode: 75015

contact info
Titolo: Mr.
Nome: Olivier
Cognome: Leroy
Email: send email
Telefono: +33 1 46 54 97 89
Fax: +33 1 46 54 91 80

FR (PARIS 15) participant 1˙020˙000.00
8    GLAXOSMITHKLINE VACCINES SRL

 Organization address address: Via Fiorentina 1
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: Francesco
Cognome: Gulli
Email: send email
Telefono: +39 0577 243499

IT (SIENA) participant 973˙185.00
9    GOETEBORGS UNIVERSITET

 Organization address address: VASAPARKEN
city: GOETEBORG
postcode: 405 30

contact info
Titolo: Dr.
Nome: Ellen
Cognome: Rydberg
Email: send email
Telefono: +46 31 7866470
Fax: +46 31 7864355

SE (GOETEBORG) participant 973˙050.00
10    WORLD HEALTH ORGANIZATION.

 Organization address address: Avenue Appia 20
city: GENEVE
postcode: 1211

contact info
Titolo: Dr.
Nome: Brian
Cognome: Elliott
Email: send email
Telefono: 41227912678

CH (GENEVE) participant 950˙000.00
11    INSTITUT PASTEUR

 Organization address address: RUE DU DOCTEUR ROUX 25-28
city: PARIS CEDEX 15
postcode: 75724

contact info
Titolo: Dr.
Nome: Nadia
Cognome: Khelef
Email: send email
Telefono: +33 140613378
Fax: +33 140613940

FR (PARIS CEDEX 15) participant 920˙000.00
12    SCLAVO BEHRING VACCINES INSTITUTE FOR GLOBAL HEALTH S.R.L.

 Organization address address: VIA FIORENTINA 1
city: Siena
postcode: 53100

contact info
Titolo: Dr.
Nome: Audino
Cognome: Podda
Email: send email
Telefono: +39 0577 243496
Fax: +39 0577 243455

IT (Siena) participant 918˙254.00
13    EMORY UNIVERSITY NON PROFIT CORP

 Organization address address: Clifton Road, NE, 4th Floor 1599
city: Atlanta
postcode: 30322

contact info
Titolo: Dr.
Nome: Janette
Cognome: Hannam Hayes
Email: send email
Telefono: +1 404 727 2503
Fax: +1 404 727 2509

US (Atlanta) participant 850˙000.00
14    UNIVERSITE DE GENEVE

 Organization address address: Rue du General Dufour 24
city: GENEVE
postcode: 1211

contact info
Titolo: Prof.
Nome: Claire-Anne
Cognome: Siegrist
Email: send email
Telefono: 41223795778
Fax: 41223795801

CH (GENEVE) participant 830˙000.00
15    ISLENSK ERFDAGREINING EHF

 Organization address address: Sturlugata 8
city: REYKJAVIK
postcode: 101

contact info
Titolo: Mr.
Nome: Bjorgvin
Cognome: Richardsson
Email: send email
Telefono: +354 570 1900

IS (REYKJAVIK) participant 757˙672.50
16    MEDICINE IN NEED (MEND) FRANCE ASSOCIATION

 Organization address address: RUE DU BOULOI 4
city: PARIS
postcode: 75001

contact info
Titolo: Dr.
Nome: Andrew
Cognome: Schiermeier
Email: send email
Telefono: +1 617 496 1796

FR (PARIS) participant 723˙075.00
17    ACADEMISCH ZIEKENHUIS LEIDEN

 Organization address address: Albinusdreef 2
city: LEIDEN
postcode: 2333 ZA

contact info
Titolo: Ms.
Nome: Marliene
Cognome: Vos
Email: send email
Telefono: +31 71 526 1302

NL (LEIDEN) participant 570˙000.00
18    REITHERA SRL

 Organization address address: VIA GAETANO SALVATORE 486
city: Napoli
postcode: 80145

contact info
Titolo: Dr.
Nome: Rosa Margherita
Cognome: Lacatena
Email: send email
Telefono: +39 06 91329747
Fax: +39 06 97849266

IT (Napoli) participant 567˙000.00
19    UNIVERSITAET INNSBRUCK

 Organization address address: INNRAIN 52
city: INNSBRUCK
postcode: 6020

contact info
Titolo: Prof.
Nome: Beatrix
Cognome: Grubeck-Loebenstein
Email: send email
Telefono: +43 512 507 50810
Fax: +43 512 507 50899

AT (INNSBRUCK) participant 566˙984.57
20    SEATTLE BIOMEDICAL RESEARCH INSTITUTE NON PROFIT CORPORATION

 Organization address address: WESTLAKE AVENUE 307
city: SEATTLE WA
postcode: 98109 5240

contact info
Titolo: Dr.
Nome: Lynn
Cognome: Zimmerman
Email: send email
Telefono: +1 206 256 7200

US (SEATTLE WA) participant 522˙934.00
21    IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE

 Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
city: LONDON
postcode: SW7 2AZ

contact info
Titolo: Ms.
Nome: Tatjana
Cognome: Palalic
Email: send email
Telefono: +44 207 594 3866
Fax: +44 207 594 3868

UK (LONDON) participant 502˙985.00
22    ISTITUTO SUPERIORE DI SANITA

 Organization address address: Viale Regina Elena 299
city: ROMA
postcode: 161

contact info
Titolo: Dr.
Nome: Rosa Maria
Cognome: Martoccia
Email: send email
Telefono: +39 06 49902688
Fax: +39 0649903007

IT (ROMA) participant 495˙000.00
23    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

 Organization address address: Rue Michel -Ange 3
city: PARIS
postcode: 75794

contact info
Titolo: Dr.
Nome: Sandrine
Cognome: Magnetto
Email: send email
Telefono: +33 4 72445641
Fax: +33 4 78890851

FR (PARIS) participant 480˙000.00
24    FONDAZIONE HUMANITAS PER LA RICERCA

 Organization address address: Via Manzoni 56
city: ROZZANO
postcode: 20089

contact info
Titolo: Dr.
Nome: Danilo
Cognome: Petroni
Email: send email
Telefono: +39 02 8224 2435

IT (ROZZANO) participant 480˙000.00
25    FONDAZIONE PER L'ISTITUTO DI RICERC A IN BIOMEDICINA

 Organization address address: Via Vincenzo Vela 6
city: BELLINZONA
postcode: 6500

contact info
Titolo: Prof.
Nome: Giorgio
Cognome: Noseda
Email: send email
Telefono: +41 91 820 0309
Fax: +41 91 820 0305

CH (BELLINZONA) participant 480˙000.00
26    UNIVERSITEIT UTRECHT

 Organization address address: Heidelberglaan 8
city: UTRECHT
postcode: 3584 CS

contact info
Titolo: Dr.
Nome: Ricardo
Cognome: Fernandez
Email: send email
Telefono: +31 30 253 2559

NL (UTRECHT) participant 480˙000.00
27    Infectious Disease Research Institute

 Organization address address: EASTLAKE AVE E 1616 STE 400
city: SEATTLE WA
postcode: 98102

contact info
Titolo: Ms.
Nome: Karen
Cognome: Kinch
Email: send email
Telefono: +1 206 330 2503
Fax: +1 206 381 3678

US (SEATTLE WA) participant 471˙000.00
28    ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM

 Organization address address: 's Gravendijkwal 230
city: ROTTERDAM
postcode: 3015CE

contact info
Titolo: Mr.
Nome: Wim
Cognome: Leep
Email: send email
Telefono: +31 10 7044 066

NL (ROTTERDAM) participant 460˙000.00
29    Hookipa Biotech AG

 Organization address address: HELMUT QUALTINGER GASSE 2
city: Wien
postcode: 1030

contact info
Titolo: Dr.
Nome: Vera
Cognome: Baumgartl-Strasser
Email: send email
Telefono: +43 660 4923 660

AT (Wien) participant 435˙000.00
30    CROSSBETA BIOSCIENCES BV

 Organization address address: PADUALAAN 8
city: UTRECHT
postcode: 3584 CH

contact info
Titolo: Mr.
Nome: Augustinus Petrus Henricus
Cognome: Scheefhals
Email: send email
Telefono: +31 30 2532668
Fax: 31302537131

NL (UTRECHT) participant 339˙600.00
31    ABERA BIOSCIENCE AB

 Organization address address: STUREPLAN 15
city: STOCKHOLM
postcode: 11145

contact info
Titolo: Dr.
Nome: Amin
Cognome: Omrani
Email: send email
Telefono: 46707983639

SE (STOCKHOLM) participant 314˙937.60
32    VACCIBODY AS

 Organization address address: GAUSTADALLEEN 21
city: OSLO
postcode: 349

contact info
Titolo: Dr.
Nome: Ole Henrik
Cognome: Brekke
Email: send email
Telefono: 4722958193

NO (OSLO) participant 292˙438.00
33    DUOTOL AB

 Organization address address: KORVETTGATAN 1D
city: VASTRA FROLUNDA
postcode: 421 74

contact info
Titolo: Prof.
Nome: Jan
Cognome: Holmgren
Email: send email
Telefono: +46 31 7866201
Fax: +46 31 298685

SE (VASTRA FROLUNDA) participant 290˙000.00
34    ALTA RICERCA E SVILUPPO IN BIOTECNOLOGIE SRLU

 Organization address address: VIA FIORENTINA 151
city: SIENA
postcode: 53100

contact info
Titolo: Dr.
Nome: Cristiana
Cognome: Tozzi
Email: send email
Telefono: +39 0577 50518
Fax: +39 0577 593815

IT (SIENA) participant 265˙000.00
35    PEVION BIOTECH AG

 Organization address address: WORBLENTALSTRASSE 32
city: ITTIGEN
postcode: 3063

contact info
Titolo: Mr.
Nome: Roger
Cognome: Kalchofner
Email: send email
Telefono: 410316000000
Fax: 410316000000

CH (ITTIGEN) participant 262˙541.00
36    VALNEVA AUSTRIA GMBH

 Organization address address: CAMPUS VIENNA BIOCENTER 3
city: WIEN
postcode: 1030

contact info
Titolo: Dr.
Nome: Anja
Cognome: Obrowsky
Email: send email
Telefono: 431206000000

AT (WIEN) participant 236˙756.52
37    SIGMOID PHARMA LIMITED

 Organization address address: THE INVENT CENTRE, DUBLIN CITY UNIVERSITY
city: DUBLIN
postcode: 9

contact info
Titolo: Ms.
Nome: Ross
Cognome: Maureen
Email: send email
Telefono: 35317007452

IE (DUBLIN) participant 208˙080.00
38    Department of Health

 Organization address address: Quarry House, Quarry Hill
city: Leeds
postcode: LS2 7UE

contact info
Titolo: Ms.
Nome: Amanda
Cognome: King
Email: send email
Telefono: +44 1707 641352

UK (Leeds) participant 203˙040.19
39    MICROBIOTEC srl

 Organization address address: Via delle Vigne 12
city: Monteriggioni (SI)
postcode: 53035

contact info
Titolo: Dr.
Nome: Caterina
Cognome: Cambiaggi
Email: send email
Telefono: +39 333 5275 437

IT (Monteriggioni (SI)) participant 202˙800.00
40    KING'S COLLEGE LONDON

 Organization address address: Strand
city: LONDON
postcode: WC2R 2LS

contact info
Titolo: Mr.
Nome: Paul
Cognome: Labbett
Email: send email
Telefono: +44 207 848 8184
Fax: +44 207 848 8187

UK (LONDON) participant 200˙400.00
41    STICHTING TUBERCULOSIS VACCINE INITIATIVE

 Organization address address: Runderweg 6
city: LELYSTAD
postcode: 8219 PH

contact info
Titolo: Ms.
Nome: Anne
Cognome: Meinema
Email: send email
Telefono: +31 320 277551

NL (LELYSTAD) participant 193˙000.00
42    BIONEEDLE TECHNOLOGIES GROUP BV

 Organization address address: GARONNELAAN 10
city: EINDHOVEN
postcode: 5627 VV

contact info
Titolo: Dr.
Nome: Gijisbert
Cognome: Van De Wijdeven
Email: send email
Telefono: +31 40 226 5958

NL (EINDHOVEN) participant 154˙200.00
43    VISMEDERI SRL

 Organization address address: VIA FIORENTINA 1
city: SIENA SI
postcode: 53100

contact info
Titolo: Dr.
Nome: Chiara
Cognome: Gentile
Email: send email
Telefono: +39 0577231253

IT (SIENA SI) participant 150˙000.00
44    XBRANE BIOSCIENCE AB

 Organization address address: STUREPLAN 15
city: STOCKHOLM
postcode: 111 45

contact info
Titolo: Ms.
Nome: Joen
Cognome: Luirink
Email: send email
Telefono: +46 70 433 0449

SE (STOCKHOLM) participant 117˙062.40
45    OESTERREICHISCHE AKADEMIE DER WISSENSCHAFTEN

 Organization address address: DR. IGNAZ SEIPEL-PLATZ 2
city: WIEN
postcode: 1010

contact info
Titolo: Dr.
Nome: Beatrix
Cognome: Grubeck-Loebenstein
Email: send email
Telefono: +43 512 583919 55
Fax: +43 512 583919 8

AT (WIEN) participant 71˙015.43
46    Intercell AG

 Organization address address: Campus Vienna Biocenter 3
city: Vienna
postcode: 1030

contact info
Titolo: Ms.
Nome: Anja
Cognome: Obrowsky
Email: send email
Telefono: 431206000000
Fax: 4312060000000

AT (Vienna) participant 4˙243.48
47    HEALTH PROTECTION AGENCY HPA

 Organization address address: Central Office - 7th Floor, Holborn Gate - High Holborn 330
city: LONDON
postcode: WC1V 7PP

contact info
Titolo: Ms.
Nome: Amanda
Cognome: King
Email: send email
Telefono: +44 1707 641352
Fax: +44 1707 641051

UK (LONDON) participant 959.81
48    ARENAVAX AG

 Organization address address: WAGISTRASSE 21
city: SCHLIEREN
postcode: 8952

contact info
Titolo: Dr.
Nome: Daniel
Cognome: Pinschewer
Email: send email
Telefono: +41 79 694 5121

CH (SCHLIEREN) participant 0.00
49    GlaxoSmithKline Biologicals

 Organization address address: Rue de l'Institut 89
city: Rixensart
postcode: 1330

contact info
Titolo: Dr.
Nome: Philippe
Cognome: Denoel
Email: send email
Telefono: 3226564032

BE (Rixensart) participant 0.00
50    HOOKIPA BIOTECH GMBH

 Organization address address: JULIUS RAAB PLATZ 4
city: WIEN
postcode: 1010

contact info
Titolo: Dr.
Nome: Vera
Cognome: Baumgartl-Strasser
Email: send email
Telefono: +43 660 4923 660

AT (WIEN) participant 0.00
51    ST GEORGE'S HOSPITAL MEDICAL SCHOOL

 Organization address address: Cranmer Terrace
city: LONDON
postcode: SW17 0RE

contact info
Titolo: Dr.
Nome: Paul
Cognome: Craven
Email: send email
Telefono: +44 20 87255012
Fax: +44 20 87253487

UK (LONDON) participant 0.00
52    VALNEVA SE

 Organization address address: RUE SAINT JEAN DE DIEU 70
city: LYON
postcode: 69007

contact info
Titolo: Ms.
Nome: Anja
Cognome: Obrowsky
Email: send email
Telefono: 431206000000
Fax: 4312060000000

FR (LYON) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

immunisation    technologies    models       immune    human    genetics    routes    experimental    clinical    pre    aditec    adjuvants    sva    pathologies    biology    formulations    vaccination    responses    gender    age    generation    vaccines    impact    scientists    powerful    vectors    host    immunization    science    vaccine    groups   

 Obiettivo del progetto (Objective)

Vaccines so far have been developed mostly by following an empiric approach. To prevent and possibly cure unresolved and emerging infectious diseases we need to fully exploit the potential of the human immune system. Progress in science and technology makes it possible to achieve what was previously deemed impossible. The scope of this project is to produce knowledge necessary to develop novel and powerful immunization technologies for the next generation of human vaccines. This goal requires a multidisciplinary approach in which diverse but complementary scientific disciplines and technologies converge. Therefore some of the most competitive European research groups from public institutions and biotechs have agreed to join forces in ADITEC, together with top US groups on systems biology and adjuvants to support this enterprise. A systems biology approach will be used to study licensed and experimental vaccines in patient characterization studies and in clinical trials, to investigate the effect of adjuvants, vectors, formulations, delivery devices, routes of immunization, homologous and heterologous prime–boost schedules, as well as the impact of host factors such as age, gender, genetics and pathologies. Animal models will be used to complement human studies, and to select novel immunization technologies to be advanced to the clinic. To address these issues in a coordinated manner, ADITEC is organised on a matrix structure in which research themes and experimental approaches feed into each other. Training curricula will be created to impact on the formation of the next generation of EU researchers in the field. ADITEC scientists and institutions are part of the “Sclavo Vaccines Association” (SVA), which is dedicated to vaccines and vaccine research. SVA, acting as the coordinating institution, guarantees the long-term commitment and sustainability of this initiative, beyond the duration of ADITEC itself.

Introduzione (Teaser)

A collaborative European research programme is working on novel and powerful immunisation technologies towards the development of next-generation human vaccines.

Descrizione progetto (Article)

Vaccination is a powerful means of tackling disease by artificially inducing immunity against pathogens. In the past, vaccine development has relied solely on empirical approaches. However, advances in science and technology promise to transform vaccinology into a dynamic field.

In this context, the EU-funded http://www.aditecproject.eu/ (ADITEC) (Advanced immunization technologies) project has brought together experts in the field of immunology and vaccine development. The aim is to produce the knowledge necessary to develop novel and powerful immunisation technologies for producing effective adaptable human vaccines.

The consortium is following a systems biology approach to test a broad panel of adjuvants, live vaccine vectors, formulations and delivery devices. The focus is on vaccines against influenza H1, M. tuberculosis H56 and Chlamydia MOMP. So far, apart from classical adjuvants, the consortium has also designed second generation adjuvants. They are in the process of identifying the molecular signatures that correlate with and predict adaptive and innate responses to vaccination.

Scientists are performing pre-clinical, clinical and population-based studies to evaluate the efficacy of novel immunisation technologies and identify the optimal strategies for specific target groups. They have already analysed how T cell-priming is elicited by different routes of vaccination in rodent models. In addition, they are assessing the impact of host factors such as age, gender, genetics and pathologies in immunisation outcome. So far, the pre-clinical work has resulted in new vaccine candidates which have been advanced in a phase I clinical trial.

Collectively, the activities of the ADITEC project respond fully to the urgent need to develop advanced immunisation technologies for safer and better vaccines. Furthermore, they will generate important new knowledge on human immune responses associated with these improved vaccines and will enable informed decisions on their implementation.

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