NEUROXSYS

Genomic Regulatory Systems of Human X-linked neurological diseases

 Coordinatore UNIVERSITETET I BERGEN 

 Organization address address: Museplassen 1
city: BERGEN
postcode: 5007

contact info
Titolo: Ms.
Nome: Inger
Cognome: Gjesdahl
Email: send email
Telefono: 4755584965
Fax: 4755584991

 Nazionalità Coordinatore Norway [NO]
 Sito del progetto http://neuroxsys.net/
 Totale costo 3˙970˙394 €
 EC contributo 2˙997˙197 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2007-B
 Funding Scheme CP-FP
 Anno di inizio 2009
 Periodo (anno-mese-giorno) 2009-06-01   -   2012-11-30

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    UNIVERSITETET I BERGEN

 Organization address address: Museplassen 1
city: BERGEN
postcode: 5007

contact info
Titolo: Ms.
Nome: Inger
Cognome: Gjesdahl
Email: send email
Telefono: 4755584965
Fax: 4755584991

NO (BERGEN) coordinator 423˙735.00
2    THE UNIVERSITY OF SYDNEY

 Organization address address: The University of Sydney
city: SYDNEY
postcode: 2006

contact info
Titolo: Ms.
Nome: Jodie
Cognome: Sirone
Email: send email
Telefono: 293510786

AU (SYDNEY) participant 651˙803.00
3    Karlsruher Institut fuer Technologie

 Organization address address: Kaiserstrasse 12
city: Karlsruhe
postcode: 76131

contact info
Titolo: Ms.
Nome: Natascha
Cognome: Wallburg
Email: send email
Telefono: +49 7247 825414
Fax: +49 7247 825403

DE (Karlsruhe) participant 520˙361.00
4    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

 Organization address address: Rue Michel -Ange 3
city: PARIS
postcode: 75794

contact info
Titolo: Ms.
Nome: Michele
Cognome: Saumon
Email: send email
Telefono: 33169823264
Fax: 33169823333

FR (PARIS) participant 448˙481.00
5    UNIVERSITY COLLEGE LONDON

 Organization address address: GOWER STREET
city: LONDON
postcode: WC1E 6BT

contact info
Titolo: Mr.
Nome: Michael
Cognome: Browne
Email: send email
Telefono: 442077000000
Fax: 442077000000

UK (LONDON) participant 309˙598.00
6    ECOLE NORMALE SUPERIEURE

 Organization address address: "45, RUE D'ULM"
city: PARIS CEDEX 05
postcode: 75230

contact info
Titolo: Ms.
Nome: Nathalie
Cognome: Majua
Email: send email
Telefono: 33144322900
Fax: 33144322933

FR (PARIS CEDEX 05) participant 247˙779.00
7    THE UNIVERSITY OF EDINBURGH

 Organization address address: OLD COLLEGE, SOUTH BRIDGE
city: EDINBURGH
postcode: EH8 9YL

contact info
Titolo: Ms.
Nome: Valerie
Cognome: Renton
Email: send email
Telefono: 441312000000
Fax: 441312000000

UK (EDINBURGH) participant 243˙204.00
8    MEDICAL RESEARCH COUNCIL

 Organization address address: NORTH STAR AVENUE POLARIS HOUSE
city: SWINDON
postcode: SN2 1FL

contact info
Titolo: Dr.
Nome: Kate
Cognome: Wilson
Email: send email
Telefono: 441313000000
Fax: 441315000000

UK (SWINDON) participant 152˙236.00
9    HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH

 Organization address address: Ingolstaedter Landstrasse 1
city: MUENCHEN
postcode: 85764

contact info
Titolo: Dr.
Nome: Juergen
Cognome: Ertel
Email: send email
Telefono: -31873062
Fax: -31873906

DE (MUENCHEN) participant 0.00

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

grbs    disease    neuroxsys    zebrafish    genes    map    generate    implicated    sequences    regions    regulatory    gene    human    brain       chromosome   

 Obiettivo del progetto (Objective)

'NeuroXsys will generate regulatory maps and models of the human X chromosome based on evolutionary conservation, with special attention to genes and regions implicated in X-linked neurological diseases. Vertebrate chromosomes are subdivided into domains of genomic regulatory blocks (GRBs) and NeuroXsys aims to map all GRBs on the X chromosome through bioinformatic approaches, extract gene regulatory sequences, and model their activity through transgenic reporter assays in the zebrafish juvenile and adult brain. One of the major deliverables of this project will be the publication of an online database that achieves correlation of disease genes ordered with respect to their regulatory regions and their experimentally and bioinformatically assessed function. NeuroXsys will seek to identify human disease mutations in neural gene regulatory elements. Implicated elements will be studied as regulators at single cell resolution in the zebrafish and mouse brain, defining expression patterns driven by the normal and mutant human regulatory DNA sequences. NeuroXsys will generate a regulatory map of a human chromosome.'

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