ENVISION

European NoVel Imaging Systems for ION therapy

 Coordinatore EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH 

 Organization address address: ROUTE DE MEYRIN CERN
city: GENEVA 23
postcode: 1211

contact info
Titolo: Prof.
Nome: Manjit
Cognome: Dosanjh
Email: send email
Telefono: +41 22 767 17 91
Fax: +41 22 767 2700

 Nazionalità Coordinatore Switzerland [CH]
 Totale costo 9˙305˙864 €
 EC contributo 5˙996˙460 €
 Programma FP7-HEALTH
Specific Programme "Cooperation": Health
 Code Call FP7-HEALTH-2009-single-stage
 Funding Scheme CP-FP
 Anno di inizio 2010
 Periodo (anno-mese-giorno) 2010-02-01   -   2014-07-31

 Partecipanti

# participant  country  role  EC contrib. [€] 
1    EUROPEAN ORGANIZATION FOR NUCLEAR RESEARCH

 Organization address address: ROUTE DE MEYRIN CERN
city: GENEVA 23
postcode: 1211

contact info
Titolo: Prof.
Nome: Manjit
Cognome: Dosanjh
Email: send email
Telefono: +41 22 767 17 91
Fax: +41 22 767 2700

CH (GENEVA 23) coordinator 1˙013˙265.25
2    TECHNISCHE UNIVERSITAET DRESDEN

 Organization address address: HELMHOLTZSTRASSE 10
city: DRESDEN
postcode: 1069

contact info
Titolo: Dr.
Nome: Lars
Cognome: Henning
Email: send email
Telefono: +49 35146342185
Fax: +49 35146339742

DE (DRESDEN) participant 675˙556.00
3    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

 Organization address address: Rue Michel -Ange 3
city: PARIS
postcode: 75794

contact info
Titolo: Ms.
Nome: Eliane
Cognome: Perret
Email: send email
Telefono: 33144964747
Fax: 33607135755

FR (PARIS) participant 532˙754.40
4    AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS

 Organization address address: CALLE SERRANO 117
city: MADRID
postcode: 28006

contact info
Titolo: Mr.
Nome: Carlos Manuel
Cognome: Abad Ruiz
Email: send email
Telefono: +34 91 566 8852
Fax: +34 91 566 89 13

ES (MADRID) participant 488˙740.47
5    ION BEAM APPLICATIONS SA

 Organization address address: Chemin du Cyclotron, 3
city: LOUVAIN LA NEUVE
postcode: 1348

contact info
Titolo: Mr.
Nome: Albert
Cognome: Blondin
Email: send email
Telefono: +32 10 475835
Fax: +32 10 475 952

BE (LOUVAIN LA NEUVE) participant 483˙232.00
6    UNIVERSITE LYON 1 CLAUDE BERNARD

 Organization address address: BOULEVARD DU 11 NOVEMBRE 1918 NUM43
city: VILLEURBANNE CEDEX
postcode: 69622

contact info
Titolo: Dr.
Nome: Javier
Cognome: Olaiz
Email: send email
Telefono: 33472697600
Fax: 33472697609

FR (VILLEURBANNE CEDEX) participant 431˙721.60
7    THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD

 Organization address address: University Offices, Wellington Square
city: OXFORD
postcode: OX1 2JD

contact info
Titolo: Ms.
Nome: Pam
Cognome: Nieto
Email: send email
Telefono: +44 1865 617311
Fax: +44 1865 617330

UK (OXFORD) participant 403˙940.00
8    ISTITUTO NAZIONALE DI FISICA NUCLEARE

 Organization address address: Via Enrico Fermi 40
city: FRASCATI
postcode: 44

contact info
Titolo: Dr.
Nome: Giuseppe
Cognome: Battistoni
Email: send email
Telefono: +39 02 50317649
Fax: +39 02 70601811

IT (FRASCATI) participant 387˙540.00
9    UNIVERSITAETSKLINIKUM HEIDELBERG

 Organization address address: IM NEUENHEIMER FELD 672
city: HEIDELBERG
postcode: 69120

contact info
Titolo: Mr.
Nome: Thorsten
Cognome: Brietz
Email: send email
Telefono: 496222000000
Fax: 496222000000

DE (HEIDELBERG) participant 326˙048.80
10    FONDAZIONE PER ADROTERAPIA ONCOLOGICA - TERA

 Organization address address: VIA PUCCINI 11
city: NOVARA
postcode: 28100

contact info
Titolo: Prof.
Nome: Fabio
Cognome: Sauli
Email: send email
Telefono: 41227673670
Fax: 41227679740

IT (NOVARA) participant 262˙060.00
11    MEDIZINISCHE UNIVERSITAET WIEN

 Organization address address: SPITALGASSE 23
city: WIEN
postcode: 1090

contact info
Titolo: Prof.
Nome: Richard
Cognome: Pötter
Email: send email
Telefono: 43404002692
Fax: 43404002693

AT (WIEN) participant 229˙120.00
12    POLITECNICO DI MILANO

 Organization address address: PIAZZA LEONARDO DA VINCI 32
city: MILANO
postcode: 20133

contact info
Titolo: Ms.
Nome: Annamaria
Cognome: Brambilla
Email: send email
Telefono: +39 0223993310
Fax: +39 0223993311

IT (MILANO) participant 179˙487.95
13    GSI HELMHOLTZZENTRUM FUER SCHWERIONENFORSCHUNG GMBH

 Organization address address: PLANCKSTRASSE 1
city: DARMSTADT
postcode: 64291

contact info
Titolo: Dr.
Nome: Johannes
Cognome: Heilmann
Email: send email
Telefono: 496160000000
Fax: 496160000000

DE (DARMSTADT) participant 175˙675.75
14    STICHTING MAASTRICHT RADIATION ONCOLOGY MAASTRO CLINIC

 Organization address address: Dr. Tanslaan 12
city: Maastricht
postcode: 6229 ET

contact info
Titolo: Dr.
Nome: Floor
Cognome: Franssen
Email: send email
Telefono: 31884455605
Fax: 31884455776

NL (Maastricht) participant 156˙494.80
15    UNIVERSITEIT GENT

 Organization address address: SINT PIETERSNIEUWSTRAAT 25
city: GENT
postcode: 9000

contact info
Titolo: Ms.
Nome: Saskia
Cognome: Vanden Broeck
Email: send email
Telefono: 3292643124
Fax: 3292643583

BE (GENT) participant 149˙615.73
16    UNIVERSIDAD DE CASTILLA - LA MANCHA

 Organization address address: CALLE ALTAGRACIA 50
city: CIUDAD REAL
postcode: 13071

contact info
Titolo: Ms.
Nome: Maria Llanos
Cognome: Carrión-Varela
Email: send email
Telefono: +34 967 599 354
Fax: +34 967 599 305

ES (CIUDAD REAL) participant 101˙207.52

Mappa


 Word cloud

Esplora la "nuvola delle parole (Word Cloud) per avere un'idea di massima del progetto.

members    ibpet    modalities    particle    tomography    pavia    treatment    imaging    precise    hadron    beam    dose    single    heidelberg    beams    irradiation    cern    cancer    industrial    tools    facilities    ion    delivered    edge    related    charged    clinical    energy    observation    line    time    tumour    indicators    envision    ions    become    techniques    therapy    deposition    camera    feasible    tissue    real    evaluation    positron    monitoring    volume    quality    particles    feedback   

 Obiettivo del progetto (Objective)

'Following the pioneering experiences which lasted several decades, particle therapy has become a recognized way of curing cancer. 2 new European dual-ion facilities (Heidelberg, Pavia) will soon become operational, followed by several others which are today at different stages of planning and construction. Hadron therapy faces the challenge of improving treatment outcomes with tools able to provide on-line a 4 dimensional feedback of the irradiation to enhance the dose conformation to the cancer volume and improve the treatment of moving organs. ENVISION is set up by 15 leading European research organisations, and 1 leading industrial partner IBA , to respond to these challenges. CERN is project coordinator and the majority of the key European experts in this field are involved, as well as the Hadron Research Facilities (Heidelberg, Pavia) who will immediately benefit from the developments foreseen in this project. A valorisation committee with members of the industrial partners has been established to maximally exploit the results. ENVISION tackles the problems of on-line Dose Monitoring and of performing accurate Quality Assurance tests by developing novel imaging modalities related to dose deposition and allow assessing the treated volume and deriving reliable indicators of the delivered dose. It concentrates on the detection of nuclear reaction products produced by the interaction of the beam with atomic nuclei of the tissue (positron emitting nuclides for ibPET, photons or light charged particles for ibSPAT). The methods are applicable to all therapy relevant ion species. The application of TOF techniques with superior time resolution to beam delivery integrated double head ibPET scanners has the potential for improving ibPET image quality. Furthermore, the real-time observation of the dose delivery process will become feasible for the 1st time, substantially reducing intervention times in case of treatment mistakes or incidents.'

Introduzione (Teaser)

Hadron therapy uses beams of charged particles (ions) to destroy tumour cells. The ENVISION project was dedicated to providing real-time imaging tools to ensure precise and complete elimination of tumours.

Descrizione progetto (Article)

Unlike in other radiotherapy methods, in hadron therapy the protons and ions deposit most of their energy at the very end of their path. This makes it possible to target a well-defined cancerous region deep in the body. This precise focus can be tuned by adjusting the energy of the incident particle beam, with reduced damage to the surrounding healthy tissues. Selective tumour irradiation requires state-of-the-art medical imaging techniques, both prior to and during treatment. Real-time imaging is needed to provide fast feedback while the dose is being delivered.

The http://cern.ch/envision (ENVISION) (European novel imaging systems for ion therapy) project developed cutting-edge imaging solutions for hadron therapy. It aimed at improving safety, outcome and lowering the cost of this highly advanced radiation therapy. A consortium of 16 European research centres and 1 industrial partner addressed the problems of online dose monitoring.

Project members developed novel imaging modalities related to dose deposition and derived reliable indicators of the delivered dose. The real-time observation became feasible by detecting the characteristic secondary emissions of the proton beams interacting with the tissue.

ENVISION also made considerable progress in refining existing techniques, such as in-beam positron emission tomography. The consortium also brought innovative technologies (in-beam single photon tomography) closer to clinical deployment, and performed proof-of-principle testing of new in-beam single-charged-particle tomography.

The project developed and built a full-size prototype of a knife-edge slit prompt gamma camera, which is currently being evaluated with clinical partners. Upon successful evaluation, this camera will provide an effective solution to improve the quality of treatments. Scientists also developed and compared methods for automated evaluation of the treatment results, optimised detector design and advanced imaging protocols.

Imaging tools designed by the ENVISION consortium offer the possibility of tumour removal with unparalleled accuracy. This, in turn, could promote hadron therapy as a safe and efficient anticancer therapy of the future.

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