Opendata, web and dolomites
H2020 projects about "druggable"
The page lists 33 projects related to the topic "druggable".
| # | |||
|---|---|---|---|
| 1 | PROPAG-AGEING | The continuum between healthy ageing and idiopathic Parkinson Disease within a propagation perspective of inflammation and damage: the search for new diagnostic, prognostic and therapeutic targets | 2015 |
| 2 | DE-ORPHAN | DEtermination of Orphan Receptor PHysiological Agonists and sigNals | 2015 |
| 3 | ISOTRAPSS | Isoform specific inhibition by transient protein state stabilization | 2015 |
| 4 | Drug-Seq | Unravelling the Genomic Targets of Drugs Using High-Throughput Sequencing | 2015 |
| 5 | EU4HIVCURE | Accelerating HIV Cure in Europe | 2016 |
| 6 | NuSiCC | Modelling the therapeutic potential of NUAK1 suppression in colorectal cancer | 2016 |
| 7 | CureCKDHeart | Targeting perivascular myofibroblast progenitors to treat cardiac fibrosis and heart failure in chronic kidney disease | 2016 |
| 8 | Wnt and CRC | Therapeutic inhibition of the oncogenic Wnt/beta-catenin pathway in mismatch repair deficient hypermutant tumors | 2017 |
| 9 | HOXA9 degradome | Deciphering the machinery involved in stability of the transcription factor HOXA9. | 2016 |
| 10 | Train2Target | An integrated mulTidisciplinary appRoach towards a new generAtIon of aNtibiotics: Targeting function and cross-talk of bacterial Envelope proTein machineries | 2017 |
| 11 | IVORIaN | RAS/C-RAF interaction: A new pharmacological target in Kras-driven lung cancer. | 2017 |
| 12 | EwiSarc | A novel in vivo platform to study and target undruggable Ewing onco-chimera. | 2017 |
| 13 | MIDAS | Predictive modelling of GPCR druggable allosteric sites | 2017 |
| 14 | SYNEME | Systems Neuroscience of Metabolism | 2017 |
| 15 | STEMpop | Mechanisms of stem cell population dynamics and reprogramming | 2018 |
| 16 | ImmunoFit | Harnessing tumor metabolism to overcome immunosupression | 2018 |
| 17 | inhibitAUTO | Towards a New Frontier in Autophagy Inhibition: The Development of a Novel Class of ChemicalProbes and Identification of Their Associated Biological Target | 2018 |
| 18 | FINDER | FINDER: FIghtiNg DEngue viRus, a novel strategy for the development of fully protective antiviralsthat act by disrupting the DENV NS3/NS5 interaction | 2018 |
| 19 | CHROMABOLISM | Chromatin-localized central metabolism regulating gene expression and cell identity | 2018 |
| 20 | UB-RASDisease | The ubiquitin system in RAS-driven disease | 2018 |
| 21 | MicroC | Agent-Based Modelling of Gene Networks to model clonal selection in the tumour microenvironment and predict therapeutic resistance | 2018 |
| 22 | METLINK | METLINK: Identification of links between cancer cell growth and metabolism genes. | 2018 |
| 23 | HiMIN | Histone H3.3 oncogenic mutations: a role in genome instability through altered DNA repair and replication fork stability? | 2018 |
| 24 | R-FunSel | In vivo functional screening via CRISPR-Cas9 to systematically identify cardiomyocyte receptors as targets for the innovative therapies for myocardial infarction and heart failure | 2019 |
| 25 | MONET | Merkel cell polyomavirus Oncogenic Network | 2019 |
| 26 | NETCONTROLOGY | Controllability of biological networks | 2020 |
| 27 | UNPACK PD-L1 | Molecular mechanism and inhibition of extracellular vesicle-mediated PD-L1 release in melanoma cells | 2020 |
| 28 | ONCORNET2.0 | ONCOgenic Receptor Network of Excellence and Training 2.0 | 2020 |
| 29 | TroyCAN | Redefining the esophageal stem cell niche – towards targeting of squamous cell carcinoma | 2020 |
| 30 | SUMiDENTITY | Deconstructing the role of SUMO on chromatin in cell identity and tissue repair | 2020 |
| 31 | MEISi | Druggable Small Molecule Inhibitor of MEIS Proteins | 2019 |
| 32 | Glue2Degrade | Therapeutic hijacking of E3 Ligases | 2020 |
| 33 | xenCAKUT | CRISPR/Cas9 based kidney disease modeling to elucidate novel genetic drivers and therapeutic targets in X. tropicalis | 2020 |