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GLAM

Laser Multiplexed Biosensor

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

GLAM project word cloud

Explore the words cloud of the GLAM project. It provides you a very rough idea of what is the project "GLAM" about.

laser diagnostic invasive clinical monitoring settings patient capitalizes biofluids amounts diagnosis biosensors unprecedented limitations expensive point incurring free cancer label consuming decisions glam place poor care time medicine detect tissues biomarkers usable genitourinary warrant portability sophisticated biomarker patients soluble exist treatments outcome cancers sensitivity laboratories urgency manner device tumor prognosis blood resonators innovative preclinical urine approaching exquisite therapy microring oncologist multiplexing appropriate differential faster simplicity daily takes specialized treatment biopsies photonic source biological tool physicians fulfill material levels personalized data ultra

Project "GLAM" data sheet

The following table provides information about the project.

Coordinator	ACONDICIONAMIENTO TARRASENSE ASSOCIACION Organization address address: CARRER DE LA INNOVACIO 2 city: TERRASSA postcode: 8225 website: www.leitat.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	http://www.glam-project.eu
Total cost	4˙835˙584 €
EC max contribution	4˙835˙584 € (100%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-PHC-2014-two-stage
Funding Scheme	RIA
Starting year	2015
Duration (year-month-day)	from 2015-05-01 to 2019-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ACONDICIONAMIENTO TARRASENSE ASSOCIACION ACONDICIONAMIENTO TARRASENSE ASSOCIACION Organization address address: CARRER DE LA INNOVACIO 2 city: TERRASSA postcode: 8225 website: www.leitat.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (TERRASSA)	coordinator	692˙632.00
2	UNIVERSITEIT TWENTE UNIVERSITEIT TWENTE Organization address address: DRIENERLOLAAN 5 city: ENSCHEDE postcode: 7522 NB website: www.utwente.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ENSCHEDE)	participant	817˙885.00
3	FUNDACIO INSTITUT DE CIENCIES FOTONIQUES FUNDACIO INSTITUT DE CIENCIES FOTONIQUES Organization address address: AVINGUDA CARL FRIEDRICH GAUSS 3 city: Castelldefels postcode: 8860 website: www.icfo.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (Castelldefels)	participant	574˙275.00
4	FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA Organization address address: CARRER BALDIRI REIXAC PLANTA 2A 10-12 city: BARCELONA postcode: 8028 website: http://www.ibecbarcelona.eu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	participant	491˙125.00
5	NOVELIC DOO BEOGRAD-NOVI BEOGRAD NOVELIC DOO BEOGRAD-NOVI BEOGRAD Organization address address: OMLADINSKIH BRIGADA 86 P city: BEOGRAD postcode: 11070 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RS (BEOGRAD)	participant	467˙700.00
6	OBELIS SA OBELIS SA Organization address address: BOULEVARD GENERAL WAHIS 53 city: BRUXELLES postcode: 1030 website: www.obelis.net contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	participant	409˙800.00
7	ALTER TECHNOLOGY TUV NORD UK LIMITED ALTER TECHNOLOGY TUV NORD UK LIMITED Organization address address: BAIN SQUARE 5 city: LIVINGSTON postcode: EH54 7DQ website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LIVINGSTON)	participant	400˙812.00
8	UNIVERSITE LIBRE DE BRUXELLES UNIVERSITE LIBRE DE BRUXELLES Organization address address: AVENUE FRANKLIN ROOSEVELT 50 city: BRUXELLES postcode: 1050 website: www.ulb.ac.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (BRUXELLES)	participant	374˙412.00
9	WINZSOFT (ISRAEL) LTD WINZSOFT (ISRAEL) LTD Organization address address: Beit Hillel 3 city: TEL AVIV-JAFFO postcode: 67017 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (TEL AVIV-JAFFO)	participant	323˙625.00
10	STICHTING KATHOLIEKE UNIVERSITEIT STICHTING KATHOLIEKE UNIVERSITEIT Organization address address: GEERT GROOTEPLEIN NOORD 9 city: NIJMEGEN postcode: 6525 EZ website: www.radboudumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (NIJMEGEN)	participant	283˙316.00

Map

Project objective

Differential cancer diagnosis takes place daily in clinical settings for a better monitoring of patient responses to existing treatments. However outcome of this diagnosis is today still poor. Moreover, current technology to measure biomarker levels is expensive and sophisticated. Most cancer biomarker analysis use blood or biological tissues as the main source of material. These biopsies must be analyzed in specialized laboratories incurring in some limitations: high cost; specialized personnel and equipment; large amounts of biological material; long outcome delivery time; time consuming processes. Therefore it exist a real need and urgency to have new diagnostic devices that provide diagnosis, prognosis, and monitoring data faster and with exquisite ultra-sensitivity on time to take the appropriate decisions to improve personalized diagnosis and therapy. The aim of GLAM project is to provide an innovative device to fulfill these requirements using soluble biomarkers for personalized diagnosis and therapy monitoring. Specifically we will design and develop a new diagnostic tool to detect biomarkers from biofluids obtained in a non-invasive manner, specifically focusing to urine and to genitourinary cancers, to help oncologist to take better treatment decisions, approaching personalized medicine. GLAM will develop an integrated device based on novel label-free photonic biosensors with ultra-sensitivity, simplicity of use, portability, multiplexing and low cost. GLAM capitalizes on the unprecedented sensitivity achieved using laser microring resonators to detect key biomarkers in tumor development and treatment. Point of Care of the device will be carried out by preclinical and clinical sample analysis of genitourinary cancer patients to warrant personalized medicine. Importantly the GLAM unique technology will make the device also usable with other biofluids and might also be used to help physicians with other biomarker driven.

Deliverables

List of deliverables.
Report on the list of selected biomarkers to be used in later tasks	Documents, reports	2020-02-06 13:10:05
Communication toolbox	Documents, reports	2020-02-06 13:10:05

Take a look to the deliverables list in detail: detailed list of GLAM deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Michiel de Goede, Lantian Chang, Jinfeng Mu, Meindert Dijkstra, Raquel ObregÃ³n, Elena MartÃnez, Laura Padilla, Francesc Mitjans, Sonia M. Garcia-Blanco Al 2 O 3 :Yb 3+ integrated microdisk laser label-free biosensor published pages: 5937, ISSN: 0146-9592, DOI: 10.1364/ol.44.005937	Optics Letters 44/24	2020-02-06
2019	Nirmalendu Acharyya, Gregory Kozyreff Large Q Factor with Very Small Whispering-Gallery-Mode Resonators published pages: , ISSN: 2331-7019, DOI: 10.1103/physrevapplied.12.014060	Physical Review Applied 12/1	2020-02-06
2018	M. de Goede, L. Chang, M. Dijkstra, S. M. GarcÃa-Blanco Integrated Al2O3:Yb3+ microring laser for on-chip active sensing in an aqueous environment published pages: We.2.B.5. 74, ISSN: , DOI:	Proc. ECIO	2020-02-06
2019	Francesco Cutrale, Daniel Rodriguez, VerÃ³nica HortigÃ¼ela, Chi-Li Chiu, Jason Otterstrom, Stephen Mieruszynski, Anna Seriola, Enara LarraÃ±aga, Angel Raya, Melike Lakadamyali, Scott E. Fraser, Elena Martinez, Samuel Ojosnegros Using enhanced number and brightness to measure protein oligomerization dynamics in live cells published pages: 616-638, ISSN: 1754-2189, DOI: 10.1038/s41596-018-0111-9	Nature Protocols 14/2	2020-02-06
2019	Acharyya, Nirmalendu; Kozyreff, Gregory Large Q factor with very small Whispering Gallery Modes resonators published pages: , ISSN: , DOI:	1	2020-02-06
2017	Nirmalendu Acharyya, Gregory Kozyreff Multiple Critical Couplings and Sensing in a Microresonator-Waveguide System published pages: , ISSN: 2331-7019, DOI: 10.1103/PhysRevApplied.8.034029	Physical Review Applied 8/3	2020-02-06
2017	M. De Goede, M. Dijkstra, S.M. GarcÃa-Blanco Double Al2O3 microring resonator for self-referenced sensing applications published pages: , ISSN: , DOI:	Proc. ECIO	2020-02-06
2017	Samuel Ojosnegros, Francesco Cutrale, Daniel RodrÃguez, Jason J. Otterstrom, Chi Li Chiu, VerÃ³nica HortigÃ¼ela, Carolina Tarantino, Anna Seriola, Stephen Mieruszynski, Elena MartÃnez, Melike Lakadamyali, Angel Raya, Scott E. Fraser Eph-ephrin signaling modulated by polymerization and condensation of receptors published pages: 13188-13193, ISSN: 0027-8424, DOI: 10.1073/pnas.1713564114	Proceedings of the National Academy of Sciences 114/50	2020-02-06
2017	M. De Goede, M. Dijkstra, S.M. GarcÃa-Blanco High-Q Al2O3 microring resonator for sensing applications published pages: , ISSN: , DOI:	Proc ECIO	2020-02-06
2015	Anna Lagunas, Elena MartÃnez, Josep Samitier Surface-Bound Molecular Gradients for the High-Throughput Screening of Cell Responses published pages: , ISSN: 2296-4185, DOI: 10.3389/fbioe.2015.00132	Frontiers in Bioengineering and Biotechnology 3	2020-02-06
2016	A. Lagunas, B. Sasso, N. Tesson, C. Cantos, E. MartÃnez, J. Samitier Synthesis of a polymethyl(methacrylate)-polystyrene-based diblock copolymer containing biotin for selective protein nanopatterning published pages: 212-218, ISSN: 1759-9954, DOI: 10.1039/C5PY01601K	Polym. Chem. 7/1	2020-02-06
2016	Gregory Kozyreff, Nirmalendu Acharyya Dispersion relations and bending losses of cylindrical and spherical shells, slabs, and slot waveguides published pages: 28204, ISSN: 1094-4087, DOI: 10.1364/OE.24.028204	Optics Express 24/25	2020-02-06

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