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Monomer sequence control in Polymers : Toward next-generation precision materials

Total Cost €


EC-Contrib. €






Project "EURO-SEQUENCES" data sheet

The following table provides information about the project.


Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Project website
 Total cost 3˙926˙899 €
 EC max contribution 3˙926˙899 € (100%)
 Programme 1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
 Code Call H2020-MSCA-ITN-2014
 Funding Scheme MSCA-ITN-ETN
 Starting year 2015
 Duration (year-month-day) from 2015-01-01   to  2018-12-31


Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
2    QUEEN MARY UNIVERSITY OF LONDON UK (LONDON) participant 546˙575.00
6    THE UNIVERSITY OF READING UK (READING) participant 273˙287.00
7    PSA AUTOMOBILES SA FR (POISSY) participant 262˙875.00
8    UNIVERSITEIT GENT BE (GENT) participant 250˙560.00
9    IONERA TECHNOLOGIES GMBH DE (Freiburg) participant 249˙216.00


 Project objective

The aim of the project “Euro-Sequences” is to establish a multidisciplinary training network on the emerging topic of sequence-controlled polymers. It has been shown during the last 5 years that such polymers open up unprecedented options for the future of manmade materials. Indeed, similarly to biopolymers such as DNA and proteins, synthetic sequence-controlled polymers contain precisely engineered chain-microstructures that allow a fine control over their molecular, nanoscopic and macroscopic properties. For instance, these new types of polymers are relevant for applications in molecular data storage, catalysis, and nanomedicine. However, this field of research is young and therefore, fundamental and applied research is still mandatory. Thus, it seems timely and appropriate to federate top-European researchers working on that topic. The proposed network is composed of 7 academic partners and 2 companies and connects researchers with complementary expertise in areas such as organic chemistry, polymer synthesis, supramolecular chemistry, physico-chemistry and materials science. This multidisciplinary network will focus on different scientific aspects. A first important objective will be the development of facile and rapid chemical methods for ‘writing’ molecular information on polymers. In addition, analytical techniques that allow characterization and sequencing of polymers will be studied. The folding and self-assembly of sequence-controlled polymers will be also examined in order to understand the correlation between controlled primary structure and higher levels of organization. Eventually, a crucial aim of this project will be the conception of new types of plastics materials. This network will be a unique scientific environment for training PhDs. The students will conduct their research in top-European laboratories and will receive a complete training, including lectures and summer schools, on polymer chemistry, supramolecular chemistry and biomaterials.


List of deliverables.
8 publications from WP5 ESRs Documents, reports 2019-09-06 08:35:29
Outreach activities Other 2019-09-06 08:35:29
Final report Documents, reports 2019-09-06 08:35:29
At least one patent application on a new technology developed in this project Demonstrators, pilots, prototypes 2019-09-06 08:35:29
12 publications from WP2 ESRs Documents, reports 2019-09-06 08:35:29
12 Publications from WP3 ESRs Documents, reports 2019-09-06 08:35:29
Kick-off meeting Other 2019-09-06 08:35:28
EURO-SEQUENCES website Websites, patent fillings, videos etc. 2019-09-06 08:35:28

Take a look to the deliverables list in detail:  detailed list of EURO-SEQUENCES deliverables.


year authors and title journal last update
List of publications.
2018 Delphine Chan-Seng, Jeroen Louwsma, Jean-François Lutz, Stéphane Joly
Synthesis of Macromolecules Containing Phenylalanine and Aliphatic Building Blocks
published pages: 1700764, ISSN: 1022-1336, DOI: 10.1002/marc.201700764
Macromolecular Rapid Communications 39/8 2019-09-06
2018 Gianni Cavallo, Salomé Poyer, Jean-Arthur Amalian, Florent Dufour, Alexandre Burel, Christine Carapito, Laurence Charles, Jean-François Lutz
Cleavable Binary Dyads: Simplifying Data Extraction and Increasing Storage Density in Digital Polymers
published pages: 6266-6269, ISSN: 1433-7851, DOI: 10.1002/anie.201803027
Angewandte Chemie International Edition 57/21 2019-09-06
2018 Denise Karamessini, Teresa Simon-Yarza, Salomé Poyer, Evgeniia Konishcheva, Laurence Charles, Didier Letourneur, Jean-François Lutz
Abiotic Sequence-Coded Oligomers as Efficient In Vivo Taggants for the Identification of Implanted Materials
published pages: 10574-10578, ISSN: 1433-7851, DOI: 10.1002/anie.201804895
Angewandte Chemie International Edition 57/33 2019-09-06
2019 Sensu Celasun, Dario Remmler, Timm Schwaar, Michael G. Weller, Filip Du Prez, Hans G. Börner
Digging into the Sequential Space of Thiolactone Precision Polymers: A Combinatorial Strategy to Identify Functional Domains
published pages: 1960-1964, ISSN: 1433-7851, DOI: 10.1002/anie.201810393
Angewandte Chemie International Edition 58/7 2019-09-06
2018 Suzan Aksakal, Resat Aksakal, C. Remzi Becer
Thioester functional polymers
published pages: 4507-4516, ISSN: 1759-9954, DOI: 10.1039/c8py00872h
Polymer Chemistry 9/36 2019-09-06
2018 John S. Shaw, Rajendran Vaiyapuri, Matthew P. Parker, Claire A. Murray, Kate J. C. Lim, Cong Pan, Marcus Knappert, Christine J. Cardin, Barnaby W. Greenland, Ricardo Grau-Crespo, Howard M. Colquhoun
Elements of fractal geometry in the 1 H NMR spectrum of a copolymer intercalation-complex: identification of the underlying Cantor set
published pages: 4052-4061, ISSN: 2041-6520, DOI: 10.1039/c8sc00830b
Chemical Science 9/17 2019-09-06
2018 Mordjane Boukhet, Niklas F. König, Abdelaziz Al Ouahabi, Gerhard Baaken, Jean-François Lutz, Jan C. Behrends
Translocation of Sequence-Controlled Synthetic Polymers through Biological Nanopores
published pages: 182a, ISSN: 0006-3495, DOI: 10.1016/j.bpj.2017.11.1013
Biophysical Journal 114/3 2019-09-06
2017 Yamin Abdouni, Gokhan Yilmaz, C. Remzi Becer
Sequence and Architectural Control in Glycopolymer Synthesis
published pages: 229-256, ISSN: 1022-1336, DOI: 10.1002/9783527806096.ch8
Macromolecular Rapid Communication 2019-09-06
2017 Denise Karamessini, Salomé Poyer, Laurence Charles, Jean-François Lutz
2D Sequence-Coded Oligourethane Barcodes for Plastic Materials Labeling
published pages: 1700426, ISSN: 1022-1336, DOI: 10.1002/marc.201700426
Macromolecular Rapid Communications 38/24 2019-09-06
2017 Yamin Abdouni, Gökhan Yilmaz, C. Remzi Becer
Sequence Controlled Polymers from a Novel β-Cyclodextrin Core
published pages: 1700501, ISSN: 1022-1336, DOI: 10.1002/marc.201700501
Macromolecular Rapid Communications 38/24 2019-09-06
2017 Joshua O. Holloway, Suzan Aksakal, Filip E. Du Prez, C. Remzi Becer
Tailored Modification of Thioacrylates in a Versatile, Sequence-Defined Procedure
published pages: 1700500, ISSN: 1022-1336, DOI: 10.1002/marc.201700500
Macromolecular Rapid Communications 38/24 2019-09-06
2017 Jean-Arthur Amalian, Salomé Poyer, Benoit Eric Petit, Sofia Telitel, Valérie Monnier, Denise Karamessini, Didier Gigmes, Jean-François Lutz, Laurence Charles
Negative mode MS/MS to read digital information encoded in sequence-defined oligo(urethane)s: A mechanistic study
published pages: 271-278, ISSN: 1387-3806, DOI: 10.1016/j.ijms.2017.07.006
International Journal of Mass Spectrometry 421 2019-09-06
2017 Marcin L. Ślęczkowski, E. W. Meijer, Anja R. A. Palmans
Cooperative Folding of Linear Poly(dimethyl siloxane)s via Supramolecular Interactions
published pages: 1700566, ISSN: 1022-1336, DOI: 10.1002/marc.201700566
Macromolecular Rapid Communications 38/24 2019-09-06
2017 Mordjane Boukhet, Niklas Felix König, Abdelaziz Al Ouahabi, Gerhard Baaken, Jean-François Lutz, Jan C. Behrends
Translocation of Precision Polymers through Biological Nanopores
published pages: 1700680, ISSN: 1022-1336, DOI: 10.1002/marc.201700680
Macromolecular Rapid Communications 38/24 2019-09-06
2017 Steven Martens, Joshua O. Holloway, Filip. E. Du Prez
Click and Click-Inspired Chemistry for the Design of Sequence-Controlled Polymers
published pages: 1700469, ISSN: 1022-1336, DOI: 10.1002/marc.201700469
Macromolecular Rapid Communications 38/24 2019-09-06
2016 Gokhan Yilmaz, Lea Messager, Anne S. Gleinich, Daniel A. Mitchell, Giuseppe Battaglia, C. Remzi Becer
Glyconanoparticles with controlled morphologies and their interactions with a dendritic cell lectin
published pages: 6293-6296, ISSN: 1759-9954, DOI: 10.1039/C6PY01523A
Polymer Chemistry 7/41 2019-09-06
2017 Sensu Celasun, Filip E. Du Prez, Hans G. Börner
PEGylated Precision Segments Based on Sequence-Defined Thiolactone Oligomers
published pages: 1700688, ISSN: 1022-1336, DOI: 10.1002/marc.201700688
Macromolecular Rapid Communications 38/24 2019-09-06
2017 Niklas Felix König, Sofia Telitel, Salomé Poyer, Laurence Charles, Jean-François Lutz
Photocontrolled Synthesis of Abiotic Sequence-Defined Oligo(Phosphodiester)s
published pages: 1700651, ISSN: 1022-1336, DOI: 10.1002/marc.201700651
Macromolecular Rapid Communications 38/24 2019-09-06
2017 Steven Martens, Joshua O. Holloway, Filip E. Du Prez
Click and Click‐Inspired Chemistry for the Design of Sequence‐Controlled Polymers
published pages: 379-416, ISSN: , DOI: 10.1002/9783527806096.ch13
Sequence‐Controlled Polymers 2019-09-06
2017 Laurence Charles, Gianni Cavallo, Val?rie Monnier, Laurence Oswald, Roza Szweda, Jean-Fran?ois Lutz
MS/MS-Assisted Design of Sequence-Controlled Synthetic Polymers for Improved Reading of Encoded Information
published pages: 1149-1159, ISSN: 1044-0305, DOI: 10.1007/s13361-016-1543-5
Journal of The American Society for Mass Spectrometry 28/6 2019-09-06
2016 Ufuk?Saim Gunay, Beno?t?Eric Petit, Denise Karamessini, Abdelaziz Al?Ouahabi, Jean-Arthur Amalian, Christophe Chendo, Michel Bouquey, Didier Gigmes, Laurence Charles, Jean-Fran?ois Lutz
Chemoselective Synthesis of Uniform Sequence-Coded Polyurethanes and Their Use as Molecular Tags
published pages: 114-126, ISSN: 2451-9294, DOI: 10.1016/j.chempr.2016.06.006
Chem 1/1 2019-09-06
2017 Jean-Arthur Amalian, Abdelaziz Al Ouahabi, Gianni Cavallo, Niklas Felix K?nig, Salom? Poyer, Jean-Fran?ois Lutz, Laurence Charles
Controlling the structure of sequence-defined poly(phosphodiester)s for optimal MS/MS reading of digital information
published pages: , ISSN: 1076-5174, DOI: 10.1002/jms.3947
Journal of Mass Spectrometry 2019-09-06
2016 Gianni Cavallo, Abdelaziz Al Ouahabi, Laurence Oswald, Laurence Charles, Jean-Fran?ois Lutz
Orthogonal Synthesis of ?Easy-to-Read? Information-Containing Polymers Using Phosphoramidite and Radical Coupling Steps
published pages: 9417-9420, ISSN: 0002-7863, DOI: 10.1021/jacs.6b06222
Journal of the American Chemical Society 138/30 2019-09-06
2016 Chlo? Laure, Denise Karamessini, Olgica Milenkovic, Laurence Charles, Jean-Fran?ois Lutz
Coding in 2D: Using Intentional Dispersity to Enhance the Information Capacity of Sequence-Coded Polymer Barcodes
published pages: 10722-10725, ISSN: 1433-7851, DOI: 10.1002/anie.201605279
Angewandte Chemie International Edition 55/36 2019-09-06
2017 Denise Karamessini, Benoit Eric Petit, Michel Bouquey, Laurence Charles, Jean-Fran?ois Lutz
Identification-Tagging of Methacrylate-Based Intraocular Implants Using Sequence Defined Polyurethane Barcodes
published pages: 1604595, ISSN: 1616-301X, DOI: 10.1002/adfm.201604595
Advanced Functional Materials 27/3 2019-09-06
2017 Niklas Felix König, Abdelaziz Al Ouahabi, Salomé Poyer, Laurence Charles, Jean-François Lutz
A Simple Post-Polymerization Modification Method for Controlling Side-Chain Information in Digital Polymers
published pages: 7297-7301, ISSN: 1433-7851, DOI: 10.1002/anie.201702384
Angewandte Chemie International Edition 56/25 2019-09-06
2016 Suzan Aksakal, C. Remzi Becer
Poly(thioacrylate)s: expanding the monomer toolbox of functional polymers
published pages: 7011-7018, ISSN: 1759-9954, DOI: 10.1039/C6PY01721E
Polym. Chem. 7/45 2019-09-06

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